Research Profile

Modeling of biological phenomena has always been an appealing research area through which an advanced understanding of physiology for further improvement of health care is possible. In computational modeling, there is the potential to explore complex interactions in biological systems and the possibility to develop novel therapeutic interventions, rehabilitation programs, diagnostics, and surgery techniques. Despite these likely benefits, simulation-based medicine is a rare practice and the discipline has been usually constrained to research environments due to time-consuming nature of model development and solution, lack of patient-specificity, and difficulties in model parameter estimations. Our current research program focuses on advancing computational techniques to facilitiate model development process and to link multiple domains such as tissue deformations with musculoskeletal movements and also on the development of clinically oriented models and computational tools to promote simulation based decision making in the clinics.

Specific Goals

• to advance scientific understanding of biological function through computational modeling in multiple domains, scales and physics
• to provide cost-effective and efficient computational tools and interfaces to support diagnostics, decision-making, treatment and intervention design