Vincent C. Hascall, Ph.D. Profile Slides Publications

Key References

Mack, J.A., Abramson, S.R., Yixen, B., Coffin, J.C., Rothrock, J.K., Maytin, E.V., Hascall, V.C., Largman, C., Stelnicki, E.J.:   Hoxb13 knockout adult skin exhibits high levels of hyaluronan and enhanced wound healing .   FASEB J. published online May 20, 2003, 10.1096/fj.02-0959fje.   Available from http://www.fasebj.org/

de la Motte, C., Hascall, V.C., Drazba, J., Bandyopadhyay, S.K., Strong, S.A.:   Mononuclear leukocytes bind to specific hyaluronan structures on colon mucosal smooth muscle cells treated with polinosinic acid:polcytidylic acid - Inter-a-trypsin inhibitor is crucial to structure and function.   American Journal of Pathology, 163(1):121-133, 2003.

Majors, A.K., Austin, R.C., de la Motte, C.A., Pyeritz, R.E., Hascall, V.C., Kessler, S.P., Sen, G., Strong, S.A.   Endoplasmic reticulum stress induces hyaluronan-mediated leukocyte adhesion.    J. Biol. Chem., 278:47223-47231, 2003.

Wang, A., Hascall, V.C.   Hyaluronan structures synthesized by rat mesangial cells in response to hyperglycemia induce monocyte adhesion.    J. Biol. Chem., 279:10279-10285, 2004.

Passi, A., Kawamura, H., Anand, S., Sati, N., White, L.E., Hascall, V.C., Maytin, E.V.   Hyaluronan suppresses epidermal differentiation in organotypic cultures of rat keratinocytes.   Exp. Cell Research, 296:123-134, 2004.

Selbi, W., de la Motte, C., Hascall, V.C., Phillips, A.   BMP-7 modulates hyaluronan-mediated proximal tubular cell-monocyte interaction.   J. Am. Soc. Nephrol. 15: 1199-1211, 2004.

Hascall, V.C., Majors, A.K., de la Motte, C., Evanko, S.P., Wang, A., Drazba, J.A., Strong, S.A., Wight, T.N.   Intracellular hyaluronan:   a new frontier for inflammation?   Biochimica et Biophysica Acta 1673:3-12, 2004.

Lisheng, Z., Hascall, V.C., Kimata, K. Inter-a-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex. J. Biol. Chem. 279:38079-38082, 2004.

Straach, K.J., Shelton, J.M., Richardson, J.A., Hascall, V.C., Mahendroo, M.S. Regulation of hyaluronan expression during cervical ripening. Glycobiology 15:55-65, 2005.

Rugg, M.S., Willis, A.C., Mukhopadhyay, D., Hascall, V.C., Fries, E., Fulop, C., Milner, C.M., and Day, A.J.: Characterization of complexes formed between TSG-6 and inter-a-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan. J. Biol. Chem. 280:25674-25686, 2005.

Gilbert, R.J., McKeon, R.J., Darr, A., Calabro, A., Hascall, V.C., and Bellamkonda, R.V.: CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension. Molecular and Cellular Neurosciences. 29:545-558, 2005.

Mack, J.A., Ling, L., Nobuyuki S., Hascall V.C., and Maytin, E.V.: Hoxb13 upregulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model. J. Biol. Chem. 280:29904-29911, 2005.

Selbi W, et al. Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. Kidney Int  2006;70:1287-95.

Vigetti D, et al. Molecular cloning and characterization of UDP-glucose dehydrogenase from the amphibian Xenopus laevis and its involvement in hyaluronan synthesis. J Biol Chem  2006;281:8254-63.

Lauer M, Hascall V, Wang A. Heparan sulfate analysis from diabetic rat glomeruli. J Biol Chem  2007;282:843-52.

Hascall V, Bollen J, Hanson R. Impact factor PageRankled. ASBMB Today  2007 July:16-19.