Department of Biomedical Engineering
Zong-Ming Li, Ph.D.
Lerner Research Institute
9500 Euclid Avenue
Cleveland, Ohio 44195
Phone: (216) 444-1211
Fax: (216) 444-9198
Our laboratory performs orthopaedic biomechanics and rehabilitation research of the hand and upper extremity. Currently, our research activities focus on carpal tunnel mechanics and hand sensorimotor function with a clinical focus on carpal tunnel syndrome. Our work related to carpal tunnel mechanics involves studying the material and mechanical properties of the transverse carpal ligament (i.e. the volar boundary of the carpal tunnel), investigating the structural properties of the carpal tunnel, and creating a computational model for the tunnel complex. Related to hand sensorimotor function, we have been examining the pathomechanics and pathophysiology associated with carpal tunnel syndrome. Our laboratory is outfitted with cutting edge bioengineering technology including motion analysis, ultrasound imaging, magnetic resonance imaging (MRI), electromyography (EMG), electroencephalogram (EEG), robotics, and computational modeling.
In other words ...
Our laboratory studies how the hand, wrist, and arms move and how to help them heal. Our research activities focus on how muscles, nerves, and tendons and ligaments work in carpal tunnel syndrome. We study that human hand but also have made a computer model of the carpal tunnel complex. Related to hand nerve and movement studies, we have been examining what goes wrong (pathophysiology) with normal hands/wrists/arms to cause carpal tunnel syndrome. Our laboratory is outfitted with cutting-edge bioengineering technology including motion analysis, ultrasound imaging, magnetic resonance imaging (MRI), electromyography (EMG), electroencephalogram (EEG), robotics, and computational modeling.
Nataraj R, Evans PJ, Seitz WH, Li ZM (2014). Pathokinematics of precision pinch movement associated with carpal tunnel syndrome. Journal of Orthopaedic Research 32:786-792
Marquardt TL, Nataraj R, Evans PJ, Seitz WH, Li ZM (2014). Carpal tunnel syndrome impairs thumb opposition and circumduction motion. Clinical Orthopaedics and Related Research 472:2526–2533
Shen ZL, Li ZM (2013). Biomechanical interaction between the transverse carpal ligament and the thenar muscles. Journal of Applied Physiology 114:225-229
Kim DH, Marquardt TL, Gabra JN, Shen ZL, Evans PJ, Seitz WH, Li ZM (2013). Pressure-morphology relationship of a released carpal tunnel. Journal of Orthopaedic Research. 31(4):616-620.