Xianglin Yuan, Ph.D.

Project Staff

Department of Ophthalmic Research, Cole Eye Institute
Telephone: (216) 445-0424
Fax : (216) 445-3670
DrCrabbLab_4-17-06_012

ACADEMIC AND PROFESSIONAL TRAINING:

B.S. 1993, Jilin University, Jilin, P.R. China- Chemistry
M.S. 1996, Jilin University, Jilin, P.R. China- Analytical Chemistry
Ph.D.  1999, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Liaoning, P.R. China- Analytical Chemistry

PROFESSIONAL EXPERIENCE:

2006-Present Project Staff, Department of Ophthalmic Research. The Cleveland Clinic Foundation, Cleveland, OH
2005-2006 Research Support Specialist, The Rockefeller University , New York , New York
2000-2005 Research Associate and Postdoctoral Fellow, University of Tennessee Health Science Center , Memphis , Tennessee
1999-2000 Research Associate, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning, P. R. China

AWARDS:

Neuroscience Postdoctoral Fellowship Award in University of Tennessee , 2001- 2003

PUBLICATIONS:

X. Yuan , D. M. Desiderio. (2005) Human cerebrospinal fluid peptidomics. J Mass Spectrom. 40: 176-181.

X. Yuan , D. M. Desiderio. (2005) Proteomics Analysis of Prefractionated Human Lumbar Cerebrospinal Fluid. Proteomics. 5: 541-550.

X. Yuan , D. M. Desiderio. (2003) Proteomics Analysis of phosphotyrosyl-proteins in human lumbar cerebrospinal fluid. J Proteome Res. 2: 476-487.

X. Yuan , T. Russell, G. Wood, D. M. Desiderio. (2002) Analysis of the human lumbar cerebrospinal fluid proteome. Electrophoresis. 23: 1185-1196.

X. Yuan , D. M. Desiderio. (2002) Protein identification with Teflon as matrix-assisted laser desorption/ionization sample support. J Mass Spectrom. 37: 512-524.

X. Yuan , D. M. Desiderio. (2005) Proteomics Analysis of Human Cerebrospinal Fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 815: 179-189.

X. Li, T. Bürklen, X. Yuan , U. Schlattner, D. M. Desiderio, T. Wallimann and R. Homayouni. (2006) Stabilization of ubiquitous mitochondrial creatine kinase preprotein by APP family proteins. Molecular and Cellular Neuroscience. 31: 263-272.

G. M. Pasinetti, L. H. Ungar, D. J. Lange, S. Yemul, H. Deng, X. Yuan , R. H. Brown, M. E. Cudkowicz, K. Newhall, E. Peskind, S. Marcus, and L. Ho. (2006) Identification of potential cerebrospinal fluid biomarkers in amyotrophic lateral sclerosis. Neurology. 66: 1218-1222.

X. Yuan , Y. Zhang, H. Zou. (2001) Study on identification of traditional Chinese medicine-Radix Astragali by MALDI-TOF-MS. Chin J Pharm Anal. 21: 7-10.

X. Yuan , Y. Zhang, H. Zou. (2001) Study on quantitation of Ginsenoside Rg3 using MALDI-TOF-MS. Chin J Anal Chem. 29: 11-14.

X. Yuan , H. Zou, Y. Zhang. (1999) Analysis of oligosaccharide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Chin J Anal Chem. 27: 786-789.

H. Zhang, X. Yuan . X. Zhao, Q. Jin. (1997) On-line preconcentration with activated carbon for microwave plasma torch atomic emission spectrometry. Talanta. 44: 1615-1623.

Q. Jin, H. Zhang, Y. Wang, X. Yuan , W. Yang. (1994) Study of analytical performance of a low-powered microwave plasma torch in atomic emission spectrometry. J Anal Atom Spectrom. 9: 851-856.

ABSTRACTS:

X. Yuan , T. Russell, G. Wood, D. M. Desiderio. Analysis of the human lumbar cerebrospinal fluid proteome. 2002 ASMS conference.

X. Yuan , D. M. Desiderio. Protein identification with Teflon as matrix-assisted laser desorption/ionization sample support. 2002 ASMS conference.

X. Yuan , D. M. Desiderio. Analysis of phosphotyrosyl-proteins in human lumbar cerebrospinal fluid with proteomics. 2003 ASMS conference.

T. Bürklen, X. Li, U. Schlattner, X. Yuan , D. M. Desiderio, R. Homayouni and T. Wallimann. Alzheimer and cellular energetics: A link between mitochondrial creatine kinase (MtCK) and amyloid precursor proteins (APPs)? 2005 USGEB-SSN-SSBP Meeting.

B. Imai, X. Yuan , N. Chandramouli, H Deng. Characterization and quantification of glycated hemoglobins. 2006 ASMS conference.