Selected Peer Reviewed Publications (from a total of 41)

Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, Comhair SA, Xu W, Licina L, Huang L, Anand-Apte B, Yoder MC, Tuder RM, Erzurum SC (2008). Circulating Angiogenic Precursors in Idiopathic Pulmonary Arterial Hypertension. Am. J. Pathol. 172: 615-627 PMID:18258847

Aldred MA, Machado RD, James V, Morrell NW, Trembath RC (2007).
Characterization of the BMPR2 5'-untranslated region and a novel mutation in pulmonary hypertension. Am. J. Respir. Crit. Care Med. 176: 819-824 PMID: 17641158

Macconaill, LE, Aldred, MA, Lu, X, and Laframboise, T (2007). Toward accurate high-throughput SNP genotyping in the presence of inherited copy number variation. BMC Genomics. 8: 211 PMID:17608949

Aldred MA, Vijayakrishnan J, James V, Soubrier F, Gomez-Sanchez MA, Martensson G, Galie N, Manes A, Corris P, Simonneau G, Humbert M, Morrell NW, Trembath RC (2006). BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. Hum. Mutat. 27: 212-213. PMID:16429403

Machado RD, Aldred MA, James V, Harrison RE, Patel B, Schwalbe EC, Gruenig E, Janssen B, Koehler R, Seeger W, Eickelberg O, Olschewski H, Elliott CG, Glissmeyer E, Carlquist J, Kim M, Torbicki A, Fijalkowska A, Szewczyk G, Parma J, Abramowicz MJ, Galie N, Morisaki H, Kyotani S, Nakanishi N, Morisaki T, Humbert M, Simonneau G, Sitbon O, Soubrier F, Coulet F, Morrell NW, Trembath RC (2006). Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum. Mutat. 27: 121-132. PMID:16429395

Machado RD, James V, Southwood M, Harrison RE, Atkinson C, Stewart S, Morrell NW, Trembath RC, Aldred MA (2005). Investigation of second genetic hits at the BMPR2 locus as a modulator of disease progression in familial pulmonary arterial hypertension. Circulation 111: 607-613. PMID:15699281, PDF

Harrison RE, Berger R, Haworth SG, Tulloh R, Mache CJ, Morrell NW, Aldred MA, Trembath RC (2005). Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood. Circulation 111: 435-441. PMID:15687131, PDF

Aldred MA, Sanford RO, Thomas NS, Barrow MA, Wilson LC, Brueton LA, Bonaglia MC, Hennekam RC, Eng C, Dennis NR, Trembath RC (2004). Molecular analysis of 20 patients with 2q37.3 monosomy: definition of minimum deletion intervals for key phenotypes. J. Med. Genet. 41: 433-439. PMID:15173228, PDF

Aldred MA, Huang Y, Liyanarachchi S, Pellegata NS, Gimm O, Jhiang S, Davuluri RV, de la Chapelle A, Eng C (2004). Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes. J Clin Oncol 22: 3531-3539. PMID:15337802, PDF

Aldred MA, Ginn-Pease ME, Morrison CD, Popkie AP, Gimm O, Hoang-Vu C, Krause U, Dralle H, Jhiang SM, Plass C, Eng C (2003). Caveolin-1 and caveolin-2, together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis. Cancer Res. 63:2864-2871. PMID:12782592, PDF

Aldred MA, Morrison C, Gimm O, Hoang-Vu C, Krause U, Dralle H, Jhiang S, Eng C (2003). Peroxisome proliferator-activated receptor gamma is frequently downregulated in a diversity of sporadic nonmedullary thyroid carcinomas. Oncogene 22:3412-3416. PMID:12776192

Aldred MA, Aftimos S, Hall C, Waters K, Thakker RV, Trembath RC, Brueton L (2002). Constitutional deletion of chromosome 20q in two patients affected with Albright hereditary osteodystrophy. Am. J. Med. Genet. 113:167-172. PMID:12407707

Aldred MA, Bagshaw RJ, Macdermot K, Casson D, Murch SH, Walker-Smith JA, Trembath RC (2000). Germline mosaicism for a GNAS1 mutation and Albright hereditary osteodystrophy. J. Med. Genet. 37: E35. PMID:11073544, PDF

Aldred MA, Trembath RC (2000). Activating and inactivating mutations in the human GNAS1 gene. Hum. Mutat. 16: 183-189. PMID:10980525