Title of Study: Familial Barrett Esophagus and Esophageal Adenocarcinoma
Nickname: FBE Study
Principal Investigator: Charis Eng, MD, PhD
Genetic Counselor Coordinator: Brandie Heald, MS (email: leachb@ccf.org)
Enrollment for this study must be facilitated by a health care provider (genetic counselor, doctor, nurse, etc) able to take responsibility for received the patient’s results. The informed consent process must be completed by a member of our research team. See the download page for the appropriate documents needed to properly enroll your potential research patient.
This is part of a consortium study (Familial Barrett Esophagus Consortium, Charis Eng, MD, PhD, Chair), which seeks to identify and characterize the genetic causes of familial Barrett esophagus. We are seeking families with at least two relatives with BE and/or esophageal adenocarcinoma (EAC) to search for susceptibility genes. We also will accrue young onset BE (under age 60) or EAC (under age 50).
Families with two or more relatives with BE and/or esophageal adenocarcinoma (EAC), patients diagnosed with either BE under age 60 or EAC under age 50. If you have more
Enrollment Process:
Informed consent must be performed by a member of our research staff before the patient’s blood sample is obtained. Contrary to what has been acceptable in the past, it is no longer possible for you to sign and date where indicated for “Person Obtaining Consent” for your patients. There is also no longer an option to have a patient consented during a scheduled office visit. After you recognize that the patient qualifies for our study, please complete the following and send to us by fax or postal mail. To download the first three items, please click here.
• Permission to contact form (must be signed by patient)
• CCF release form (must be signed by patient)
• Banking checklist
• Pedigree
• Medical records verifying eligibility
Please do not draw the patient’s blood to send with these documents. After we have received these documents and verified that all information is complete, we will mail the patient a consent document, FBE Questionnaire, and sample collection kit and contact the subject to consent them. We will email you after we have consented the patient to keep you updated on their involvement. Samples received before the informed consent process has been completed may be destroyed.
Study Checklist