Asoke K. Mal, Ph.D. Assistant Staff Department of Molecular Genetics Lerner Research Institute / NE20 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 445-9870 Fax: (216) 444-0512 mala@ccf.org

Area of general research interest:

Epigenetic controls of myogenesis during normal and perturbed development and regeneration.

Current program:

• The role of histone modifications in epigenetic transition from proliferation into differentiation of skeletal muscle cells
• Promyogenic stimuli-mediating chromatin signaling in skeletal muscle differentiation
• Epigenetic mechanism regulating human rhabdomyosarcoma development
• Identifying of MyoD modulators by screening of small molecule chemical library

Investigators:

• Biswanath Chatterejee (Postdoctoral Fellow)
• Min-Hyung Lee (Graduate Student)

Collaborators:

• Andrei V. Gudkov, Ph.D. (Lerner Research Institute, CCF)
• Marc Penn, M.D., Ph.D. (Lerner Research Institute, CCF)