Arie Horowitz, D.Sc. Assistant Staff Department of Molecular Cardiology Lerner Research Institute / NB50 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 636-9461 Fax: (216) 445-8204 horowia@ccf.org

Area of general research interest:

Endothelial cell signaling and motility in angiogenesis; endothelial cell guidance; vessel sprouting and guidance; membrane trafficking.

Current Research:

Signaling and trafficking of tight-junction and of Rho GTPase regulatory proteins in sprouting vessels; role of trafficking in the signaling of neuropilin-1 in response to VEGF-A and semaphorin 3C.

Investigators:

• Padubidri, Anokha, Research Student
• Seerapu, Hima Bindu Reddy, Ph.D., Postdoctoral Fellow
• Wu, Chaunsen, M.D., Ph.D., Postdoctoral Fellow

Collaborators:

• Ramani Ramchandran, Ph.D., Medical College of Wisconsin
• Jay Baraban, M.D., Ph.D., Johns Hopkins Medical School
• Lars Holmgren, Ph.D., Karolinska institute, Sweden
• Panos Anastasiadis, Ph.D., Mayo Clinic

Former Trainees:

• David Seo, M.D., Resident; 1998–2000
• Masahiro Murakami, M.D., Ph.D., Postdoctoral Fellow; 1998–2001
• Mitsuru Horiba, M.D., Postdoctoral Fellow; 1999–2001
• Esther Lutgens, M.D., Ph.D., Research Associate; 2002–2003
• Miao-liang Liu, M.D., M.Sc., Instructor; 2002-2008
• Anna Salikhova, Ph.D., Postdoctoral Research Associate; 2003–2006
• Alexandra Rodman, Undergraduate trainee; 2007- 2008
• Elliot Henry, Undergraduate trainee; 2008–2008