Michelle S. Longworth, Ph.D. Assistant Staff Department of Molecular Genetics Lerner Research Institute / NE20 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 444-8082 Fax: (216) 444-0512 Email: longwom@ccf.org

Area of General Interest:

Mechanisms regulating global chromatin structure and their influence on transcription.

Current program:

• Characterization of Condensin II transcriptional regulation in different cell types and during development, using Drosophila
• Identification of novel, conserved Condensin II binding partners in Drosophila and human cells
• Understanding how the global organization of chromatin effects local transcriptional control

Investigators:

• Kavitha Sarvepalli, Ph.D. (Postdoctoral Fellow)
• Andrew Schuster (Technician)

Collaborators:

• Job Dekker, Ph.D., University of Massachusetts Medical School
• Nicholas J. Dyson, Ph.D., Massachusetts General Hospital Cancer Center