Publications:

Stacey, D.W. Three Observations That Have Changed Our Understanding of Cyclin D1 and p27 in Cell Cycle Control. Genes Cancer. 1(12):1189-1199. PMCID: PMC3092281(2010).

Hitomi, M. and Stacey, D.W. The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons. Cytometry A. 77(6):524-533 (2010).

Hitomi, M., Yang, K., Stacey, A.W. and Stacey, D.W. Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression. Mol Cell Biol. 28(17):5478-593. PMCID: PMC2519724 (2008).

Stacey, D.W. and Hitomi, M. Cell cycle studies based upon quantitative image analysis. Cytometry A. 73(4):270-278 Review (2008).

Yang, K., Hitomi, M. and Stacey, D.W. Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell. Cell Div. 1:32 (2006).

Hitomi, M., Yang, K., Guo, Y., Fretthold, J., Harwalkar, J. and Stacey, D.W. p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point. Cell Cycle. 5(19):2281-9 (2006).

Yang, K., Guo, Y., Stacey, W.C., Harwalker, J., Fretthold, J., Hitomi, M. and Stacey, D.W. Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels. BMC Cell Biol. 7:33 (2006).

Guo, Y., Yang, K., Harwalkar, J., Nye, J.M., Mason, D.R., Garrett, M.D., Hitomi, M. and Stacey, D.W. Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene. 24(16):2599-2612 (2005).

Sa, G., Guo, Y. and Stacey, D.W. The regulation of S phase initiation by p27Kip1 in NIH3T3 cells. Cell Cycle. 4(4):618-627 (2005).

Guo, Y., Harwalkar, J., Stacey, D.W. and Hitomi, M. Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal. Oncogene. 24(6):1032-1042 (2005).

Sa, G. and Stacey, D.W. P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase. Exp. Cell Res. 300(2):427-439 (2004).

Stacey, D.W. Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells. Curr. Opin. Cell Biol. 15(2):158-163 (2003).

Guo, Y., Stacey, D.W. and Hitomi, M. Post-transcriptional regulation of cyclin D1 expression during G2 phase. Oncogene. 21:7545-7556 (2002).

Sa. G., Hitomi, M., Harwalker, J., Stacey, A.W., Chen, G. and Stacey, D.W. Ras is active throughout the cell cycle, but is able to induce cyclin D1 only during G2 phase. Cell Cycle 1:50-58 (2002).

Hitomi, M. and Stacey, D.W. Ras-dependent cell cycle commitment during G2 phase. FEBS Lett. 490:123-131 (2001).

Hitomi, M. and Stacey, D.W. Cyclin D1 production in cycling cells depends on ras in a cell-cycle-specific manner. Curr. Biol. 9:1075-1084 (1999).

Hitomi, M. and Stacey, D.W. Cellular ras and cyclin D1 are required during different cell cycle phases in cycling NIH 3T3 cells. Mol Cell Biol. 119 (7):4623-32 (1999).