Publications

Ghosal K and Pimplikar SW. “Aging and excitotoxic stress exacerbate neural circuit reorganization in APP intracellular domain (AICD) transgenic mice” Neurobiol Aging (2010, in press).

Ghosal K, Vogt, DL, Liang M, Shen Y, Lamb BT, Pimplikar SW. “Alzheimer’s disease-like pathological feature in transgenic mice expressing the APP intracellular domain” Proc. Natl. Acad. Sci. USA 106, 18367-72, (2009).

Vogt DL, Thomas D, Galvan V, Bredesen DE, Lamb BT, Pimplikar SW. “ Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain” Neurobiol Aging (2009, in press).

Joshi P, Liang JO, Dimonte K, Sullivan J, Pimplikar SW. “Amyloid precursor protein is required for convergent-extension movements during zebrafish development” Dev. Biol. 335, 1-11 (2009)

Briand S, Facchinett P, Clamagiran C, Madeir A, Pomme J, Pimplikar SW, Allinquant B. “PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface” Neurobiol Aging (2009, in press).

Pimplikar SW “Reassessing the Amyloid Cascade hypothesis of Alzheimer’s disease” Int J Biochem Cell Biol 41, 1261-1268 (2009). [NIHMS ID 103956]

Varvel NH, Bhaskar K, Patil A, Pimplikar SW, Herrup K, Lamb BT. “Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease” J Neurosci 28, 10786-92 (2008).

Pardossi-Piquard R., Dunys J., Kawarai T., Sunyach C., Alves da Costa C., Vincent B., Sévalle J., Pimplikar S. W., St George-Hyslop P., and Checler F. “Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP.” Neuron 46, 541–554 (2007)

Ryan  K.  and Pimplikar S.W. “Activation of GSK-3 and Phosphorylation of CRMP2 in Transgenic Mice Expressing APP Intracellular Domain”  J. Cell Biol.  171, 327-335 (2005)

Hsu CL, Chen YL, Ting HJ, Lin WJ, Yang Z, Zhang Y, Wang L, Wu CT, Chang HC, Yeh S, Pimplikar SW, Chang C. "Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth" Mol. Endocrinol. 19, 350-61 (2005)

Tartakoff AM, Matera AG, Pimplikar S.W, Weimbs T. "Regulation of nuclear functions-nucleocytoplasmic transport in context" Eur. J. Cell Biol. 83, 185-92. (2004)

Benboudjema L., Mulvey M., Gao Y., Pimplikar, S.W. and Mohr I. “Association of the Herpes Simplex Virus Type-1 Us11 Gene Product with the Cellular Kinesin Light-chain Related Protein PAT1 Results in the Redistribution of Both Polypeptides” J. Virol. 77, 9192-9203 (2003)

Gao  Y.  and Pimplikar S.W. “The g-secretase cleaved C-terminal  fragment of APP mediates signaling to the nucleus”  Proc. Natl. Acad. Sci. 98, 14979-14984 (2001)

Zheng P., Eastman J., Vande Pol, S. and Pimplikar, S.W. "PAT1, A Microtubule-Interacting Protein, Recognizes the Basolateral Sorting Signal of Amyloid Precursor Protein" Proc. Natl. Acad. Sci. 95, 14745-14750 (1998)

Mazanec M.B., Huang Y.T., Pimplikar S.W. and Lamm M.E. "Mechanisms of inactivation of respiratory viruses by IgA, including intraepithelial neutralization" Semi. Virol. 7, 285-292 (1996)

Pimplikar S.W. and Simons K. "Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells" J. Biol. Chem. 269, 19054-19059 (1994)

Pimplikar S.W., Ikonen E. and Simons K. "Basolateral transport in streptolysin-O permeabilized MDCK cells" J.Cell Biol. 125, 1025-1035 (1994)

Pimplikar S.W. "Use of toxins in studying epithelial membrane transport" in Bacterial Protein Toxins, Freer et al. (eds.), Gustav Fischer, Stuttgart (1994)

Pimplikar S.W. and Simons K. "Regulation of apical transport in epithelial cells by a Gs class of heterotrimeric G protein" Nature 362, 456-458 (1993)

Pimplikar S.W. and Simons K. "Role of heterotrimeric G proteins in polarized membrane transport" J Cell Sci.  (suppl) 17, 27-32 (1993)

Huber L., Pimplikar S.W., Parton R.G., Virta H., Zerial M., and Simons K "Rab 8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane"  J Cell Biol. 123, 35-45 (1993)

Pimplikar S.W. and Huttner W.B. "Chromogranin B (Secretogranin I), a secretory protein of the regulated pathway, is also present in a tightly membrane-associated form in PC12 cells" J. Biol. Chem. 267, 4110-4118 (1992)

Kobayashi T., Pimplikar S.W., Parton R.G., Bhakdi S., and Simons K "Sphingolipid transport from the trans-Golgi network to the apical surface in permeabilized MDCK cells" FEBS Letters  300, 227-231 (1992)

Simons K., Dupree P., Fiedler K., Huber L., Kobayashi T., Kurzchalia T., Pimplikar S.W., Parton R., and Dotti C. "The biogenesis of cell surface polarity in epithelial cells and neurons"  Cold Spring Harbour Laboratory Symposium 57  "The cell Surface". (1992)

Chanat, E., Pimplikar S.W., Stinchcombe, J.C., and Huttner W.B. "What the Granins tell us about the formation of secretory granules in neuroendocrine cells" Cell Biophys. 19, 85-91 (1991)

Reithmeier R.A.F., Lieberman D.M., Casey J.R., Pimplikar S.W., Werner P.K., See H. and Pirraglia C. "Structure and Function of the Band 3 Cl/HCO3 Transporter". Annals N.Y. Acad. Sci. 574, 75-83 (1989)

Pimplikar S.W. and Reithmeier R.A.F. "Identification, Purification and Characterization of a Stilbene Disulfonate Binding Glycoprotein From Canine Kidney Brush Border Membranes: A  Candidate for a Renal Anion Exchanger" J. Biol. Chem. 263, 4485-4493 (1988)

Pimplikar S.W. and Reithmeier R.A.F. "Studies on the Interaction of Matrix-bound Inhibitor with Band 3, The Anion Transport Protein of Human Erythrocyte Membranes." Biochim. Biophys. Acta  942, 253-261 (1988)

Pimplikar S.W. "Affinity Chromatography of the Anion Transport Protein from Erythrocytes and a Novel Glycoprotein from Kidney". Ph.D. thesis. University of Alberta, Edmonton, Alberta, Canada. (1987) 

Pimplikar S.W. and Reithmeier R.A.F. "Affinity  Chromatography of Band 3, the Anion Transport Protein of Erythrocyte Membranes". J. Biol. Chem. 261, 9770-9778 (1986) 

Pimplikar S.W. and Malhotra S.K. "Analysis of Erythrocyte Membrane Proteins from Dystrophic Hamsters." FEBS Letters 156, 141-144 (1983)

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