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Notations Newsletter, October 2009

Consortium of Researchers Discover Retroviral Link to Chronic Fatigue Syndrome

Robert Silverman, PhD Scientists have discovered a potential retroviral link to chronic fatigue syndrome, known as CFS, a debilitating disease that affects millions of people in the United States and many more women than men. Read Full Article

Alzheimer's Origins More Complex Than Thought, May Involve 'New' Culprit

Sanjay W. Pimplikar, PhD For years, conventional wisdom held that a substance called amyloid beta, which causes the plaque deposits characteristic of Alzheimer's disease, was the primary cause of the disease. But recent research at Lerner Research Institute has found that the origins of the neurodegenerative disease are more complex -- and that another culprit might share as much, if not more, of the blame. Read Full Article

Damaged Blood-Brain Barrier May Protect Lung Cancer Patients Against Brain Metastases

Damir Janigro, PhD Cleveland Clinic researchers have found that damage to the blood-brain barrier (BBB) may actually protect lung cancer patients from developing brain metastases. Read Full Article

Major Project Focused on Infection and Nervous System Demyelination Funded

Conni Bergmann, PhD The Institute has received a five-year, $8.2 million Program Project Grant focused on the persistence of central nervous system infection associated with the loss of the myelin sheath and neuronal function. It is funded by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health. Read Full Article

NIH Selects Cleveland Clinic to Launch 2009 H1N1 Influenza Vaccine Trial in People with Asthma

Serpil Erzurum, MD The National Institutes of Health selected the Lerner Research Institute as one of seven sites at which to launch the first government-sponsored clinical trial to determine what dose of the 2009 H1N1 influenza vaccine is needed to induce a protective immune response in people with asthma, especially those with severe disease. Read Full Article

Institute Welcomes Two New Faculty Members

The Institute recently welcomed Zong-Ming Li, PhD, who focuses on hand biomechanics and upper limb rehabilitation and Matthew Summers, PhD, who studies the regulation of cellular proliferation. Read Full Article

Latest Grant Recipients

Fifteen Institute researchers recently received new grants totaling more than $16 million. Read Full Article