Dr. Laura E. Nagy Lab
Laura E. Nagy, Ph.D.
Staff, Department of Pathobiology
The research in my laboratory is aimed at understanding how chronic alcohol consumption contributes to chronic diseases, such as liver disease and diabetes.
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April 16th 2012
Sanjoy Roychowdhury, PhD, Nagy Lab, was featured in The Foundation for Alcohol Research's April eNewsletter. [...]
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August 9th 2011
Laura E. Nagy, PhD, Pathobiology, was awarded a 5-year $1.8M R01 from NIH/National Institute on Alcohol Abuse and Alcoholism NIAAA: "Heme oxygenase-1 and alcoholic liver disease".
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November 15th 2010
Gail Cresci, PhD, RD, CNSD, LD, as Project Research Staff in the lab of Laura Nagy, PhD, Pathobiology is featured in November's Cleveland Clinic Research News [...]
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October 5th 2010
Lerner Research Institute forms Center for Liver Disease Research (CLDR), under the Directorship of Laura E. Nagy, PhD. [...]
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May 4th 2010
Dian Chiang, MD, MPH, Digestive Disease Institute and laboratory of Laura Nagy, PhD, is a recipient of the Dean Thiel Postdoctoral Research Fellowship Award by the American Liver Foundation (ALF). [...]
The research in my laboratory is aimed at understanding how chronic alcohol consumption contributes to chronic diseases, such as liver disease and diabetes.
Research Projects
- Studying the effects of ethanol on the innate immune system
- Understanding how ethanol disrupts signal transduction via the toll-like receptors, leading to disruption of the transcriptional and post-transcriptional regulation of cytokine production
- Investigating how ethanol causes insulin resistance in adipose tissue, leading to impaired GLUT4 vessicle trafficking and glucose transport, as well as abnormal regulation of triglyceride homeostasis.
- Mark Barnes, B.S.
- Dola Das, Ph.D.
- Antoinette D. Hillian, Ph.D.
- James Kasper, Ph.D.
- Megan McMullen, B.A.
- Sorana Pisano, B.S
- Sanjoy Roychowdhury, Ph.D.
- Gaurisankar Sa, Ph.D.
- Becky Sebastian, M.S.
- Hui Tang, Ph.D.
- National Institutes of Health
- Regulation of Kupffer cell signal transduction by ethanol
This project investigates the effects of chronic ethanol on Kupffer cell dependent signal transduction.
- National Institutes of Health
- Insulin mediated glucose transport: disruption by ethanol
This project investigates the effects of chronic ethanol on regulation of glucose transport in adipocytes and muscles.
- National Institutes of Health
- Egr-1: A candidate molecular target of ethanol action
This project explores the role of the transcription factor, Egr-1, in the development of alcoholic liver injury.
- National Institutes of Health
- Egr-1 and EtOH-induced hepatic leukocyte recruitment
NRSA fellowship to Michele T. Pritchard
- National Institutes of Health
- Complement and liver injury
This project investigates the contribution of complement activation in ethanol-induced liver injury.
- National Institutes of Health
- Thioredoxin and ethanol-induced liver injury
NRSA fellowship to Jessica Cohen
