The publications below have been supported by the Center and result from collaborations between Center investigators. (Center members are in bold).

1: Neuman MG, Seitz HK, French SW, Malnick S, Tsukamoto H, Cohen LB, Hoffman P, Tabakoff B, Fasullo M, Nagy LE, Tuma PL, Schnabl B, Mueller S, Groebner JL, Barbara FA, Yue J, Nikko A, Alejandro M, Brittany T, Edward V, Harrall K, Saba L, Mihai O. Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research. Biomedicines. 2020 Mar 18;8(3). pii: E63. doi: 10.3390/biomedicines8030063. Review. PubMed PMID: 32197424.

2: Neumann CKA, Silver DJ, Venkateshwari V, Zhang R, Traughber CA, Przybycin C, Bayik D, Smith JD, Lathia JD, Rini BI, Brown JM. MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma. Mol Metab. 2020 Apr;34:136-145. doi: 10.1016/j.molmet.2020.01.011. Epub 2020 Feb 3. PubMed PMID: 32180553; PubMed Central PMCID: PMC7033598.

3: Han Y, Glueck B, Shapiro D, Miller A, Roychowdhury S, Cresci GAM. Dietary Synbiotic Supplementation Protects Barrier Integrity of Hepatocytes and Liver Sinusoidal Endothelium in a Mouse Model of Chronic-Binge Ethanol Exposure. Nutrients. 2020 Jan 31;12(2). pii: E373. doi: 10.3390/nu12020373. PubMed PMID: 32023885; PubMed Central PMCID: PMC7071303.

4: Welch N, Dasarathy J, Runkana A, Penumatsa R, Bellar A, Reen J, Rotroff D, McCullough AJ, Dasarathy S. Continued muscle loss increases mortality in cirrhosis: Impact of aetiology of liver disease. Liver Int. 2019 Dec 31. doi: 10.1111/liv.14358. [Epub ahead of print] PubMed PMID: 31889396.

5: Choucair I, Nemet I, Li L, Cole MA, Skye SM, Kirsop JD, Fischbach MA, Gogonea V, Brown JM, Tang WHW, Hazen SL. Quantification of bile acids: a mass spectrometry platform for studying gut microbe connection to metabolic diseases. J Lipid Res. 2020 Feb;61(2):159-177. doi: 10.1194/jlr.RA119000311. Epub 2019 Dec 9. PubMed PMID: 31818878; PubMed Central PMCID: PMC6997600.

6: Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM. Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. Elife. 2019 Oct 17;8. pii: e49882. doi: 10.7554/eLife.49882. PubMed PMID: 31621579; PubMed Central PMCID: PMC6850774.

7: Zhou Z, Ye TJ, DeCaro E, Buehler B, Stahl Z, Bonavita G, Daniels M, You M. Intestinal SIRT1 Deficiency Protects Mice from Ethanol-Induced Liver Injury by Mitigating Ferroptosis. Am J Pathol. 2020 Jan;190(1):82-92. doi: 10.1016/j.ajpath.2019.09.012. Epub 2019 Oct 11. PubMed PMID: 31610175; PubMed Central PMCID: PMC6943377.

8: Kumar A, Davuluri G, Welch N, Kim A, Gangadhariah M, Allawy A, Priyadarshini A, McMullen MR, Sandlers Y, Willard B, Hoppel CL, Nagy LE, Dasarathy S. Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy. Free Radic Biol Med. 2019 Dec;145:284-299. doi: 10.1016/j.freeradbiomed.2019.09.031. Epub 2019 Sep 28. PubMed PMID: 31574345; PubMed Central PMCID: PMC6910229.

9: McCullough A, Previs SF, Dasarathy J, Lee K, Osme A, Kim C, Ilchenko S, Lorkowski SW, Smith JD, Dasarathy S, Kasumov T. HDL flux is higher in patients with nonalcoholic fatty liver disease. Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E852-E862. doi: 10.1152/ajpendo.00193.2019. Epub 2019 Sep 10. PubMed PMID: 31503515; PubMed Central PMCID: PMC6879863.

10: Yodoshi T, Orkin S, Arce-Clachar AC, Bramlage K, Liu C, Fei L, El-Khider F, Dasarathy S, Xanthakos SA, Mouzaki M. Vitamin D deficiency: prevalence and association with liver disease severity in pediatric nonalcoholic fatty liver disease. Eur J Clin Nutr. 2020 Mar;74(3):427-435. doi: 10.1038/s41430-019-0493-y. Epub 2019 Aug 23. PubMed PMID: 31444465.

11: Bellos DA, Sharma D, McMullen MR, Wat J, Saikia P, de la Motte CA, Nagy LE. Specifically Sized Hyaluronan (35 kDa) Prevents Ethanol-Induced Disruption of Epithelial Tight Junctions Through a layilin-Dependent Mechanism in Caco-2 Cells. Alcohol Clin Exp Res. 2019 Sep;43(9):1848-1858. doi: 10.1111/acer.14140. Epub 2019 Jul 16. PubMed PMID: 31237689; PubMed Central PMCID: PMC6721967.

12: Kim A, Saikia P, Nagy LE. miRNAs Involved in M1/M2 Hyperpolarization Are Clustered and Coordinately Expressed in Alcoholic Hepatitis. Front Immunol. 2019 Jun 7;10:1295. doi: 10.3389/fimmu.2019.01295. eCollection 2019. PubMed PMID: 31231396; PubMed Central PMCID: PMC6568035.

13: Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ. A  North American Expert Opinion Statement on Sarcopenia in Liver Transplantation. Hepatology. 2019 Nov;70(5):1816-1829. doi: 10.1002/hep.30828. Epub 2019 Aug 19. PubMed PMID: 31220351; PubMed Central PMCID: PMC6819202.

14: Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN. Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling. Cancer Discov. 2019 Sep;9(9):1248-1267. doi: 10.1158/2159-8290.CD-19-0061. Epub 2019 Jun 14. PubMed PMID: 31201181; PubMed Central PMCID: PMC6785242.

15: Davuluri G, Giusto M, Chandel R, Welch N, Alsabbagh K, Kant S, Kumar A, Kim A, Gangadhariah M, Ghosh PK, Tran U, Krajcik DM, Vasu K, DiDonato AJ, DiDonato JA, Willard B, Monga SP, Wang Y, Fox PL, Stark GR, Wessely O, Esser KA, Dasarathy S. Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia. Mol Cell Biol. 2019 Jul 29;39(16). pii: e00451-18. doi: 10.1128/MCB.00451-18. Print 2019 Aug 15. PubMed PMID: 31138664; PubMed Central PMCID: PMC6664607.

16: Bellar A, Kessler SP, Obery DR, Sangwan N, Welch N, Nagy LE, Dasarathy S, de la Motte C. Safety of Hyaluronan 35 in Healthy Human Subjects: A Pilot Study. Nutrients. 2019 May 22;11(5). pii: E1135. doi: 10.3390/nu11051135. PubMed PMID: 31121841; PubMed Central PMCID: PMC6566413.

17: Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, Lusis AJ. Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1045-1054. doi: 10.1161/ATVBAHA.119.312592. PubMed PMID: 31070450; PubMed Central PMCID: PMC6531332.

18: Zhou Z, Ye TJ, Bonavita G, Daniels M, Kainrad N, Jogasuria A, You M. Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice. Hepatol Commun. 2019 Mar 12;3(5):656-669. doi: 10.1002/hep4.1333. eCollection 2019 May. PubMed PMID: 31061954; PubMed Central PMCID: PMC6492478.

19: Poulsen KL, McMullen MR, Huang E, Kibler CD, Sheehan MM, Leng L, Bucala R, Nagy LE. Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice. Alcohol Clin Exp Res. 2019 Jul;43(7):1439-1451. doi: 10.1111/acer.14065. Epub 2019 May 14. PubMed PMID: 31009094; PubMed Central PMCID: PMC6602811.

20: Lai JC, Sonnenday CJ, Tapper EB, Duarte-Rojo A, Dunn MA, Bernal W, Carey EJ, Dasarathy S, Kamath BM, Kappus MR, Montano-Loza AJ, Nagai S, Tandon P. Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice. Am J Transplant. 2019 Jul;19(7):1896-1906. doi: 10.1111/ajt.15392. Epub 2019 May 8. PubMed PMID: 30980701; PubMed Central PMCID: PMC6814290.

21: Saha B, Tornai D, Kodys K, Adejumo A, Lowe P, McClain C, Mitchell M, McCullough A, Dasarathy S, Kroll-Desrosiers A, Barton B, Radaeva S, Szabo G. Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis. Hepatology. 2019 Oct;70(4):1134-1149. doi: 10.1002/hep.30617. Epub 2019 May 27. PubMed PMID: 30891779; PubMed Central PMCID: PMC6752989.

22: Kant S, Davuluri G, Alchirazi KA, Welch N, Heit C, Kumar A, Gangadhariah M, Kim A, McMullen MR, Willard B, Luse DS, Nagy LE, Vasiliou V, Marini AM, Weiner ID, Dasarathy S. Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations. J Biol Chem. 2019 May 3;294(18):7231-7244. doi: 10.1074/jbc.RA118.005411. Epub 2019 Mar 14. PubMed PMID: 30872403; PubMed Central PMCID: PMC6509515.

23: Plauth M, Bernal W, Dasarathy S, Merli M, Plank LD, Schütz T, Bischoff SC. ESPEN guideline on clinical nutrition in liver disease. Clin Nutr. 2019 Apr;38(2):485-521. doi: 10.1016/j.clnu.2018.12.022. Epub 2019 Jan 16. PubMed PMID: 30712783; PubMed Central PMCID: PMC6686849.

24: Sanz-Garcia C, Poulsen KL, Bellos D, Wang H, McMullen MR, Li X, Chattopadhyay S, Sen G, Nagy LE. The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute-on-chronic ethanol administration in mice. J Hepatol. 2019 May;70(5):974-984. doi: 10.1016/j.jhep.2019.01.021. Epub 2019 Jan 31. PubMed PMID: 30710579; PubMed Central PMCID: PMC6462245.

25: Gao B, Ahmad MF, Nagy LE, Tsukamoto H. Inflammatory pathways in alcoholic steatohepatitis. J Hepatol. 2019 Feb;70(2):249-259. doi: 10.1016/j.jhep.2018.10.023. Review. PubMed PMID: 30658726; PubMed Central PMCID: PMC6361545.

26: You M, Arteel GE. Effect of ethanol on lipid metabolism. J Hepatol. 2019 Feb;70(2):237-248. doi: 10.1016/j.jhep.2018.10.037. Review. PubMed PMID: 30658725; PubMed Central PMCID: PMC6436537.

27: Erickson ML, Malin SK, Wang Z, Brown JM, Hazen SL, Kirwan JP. Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults. Nutrients. 2019 Jan 16;11(1). pii: E179. doi: 10.3390/nu11010179. PubMed PMID: 30654453; PubMed Central PMCID: PMC6356515.

28: Roychowdhury S, Glueck B, Han Y, Mohammad MA, Cresci GAM. A Designer Synbiotic Attenuates Chronic-Binge Ethanol-Induced Gut-Liver Injury in Mice. Nutrients. 2019 Jan 5;11(1). pii: E97. doi: 10.3390/nu11010097. PubMed PMID: 30621265; PubMed Central PMCID: PMC6357124.

29: McCullough RL, McMullen MR, Poulsen KL, Kim A, Medof ME, Nagy LE. Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome. Front Immunol. 2018 Sep 20;9:2133. doi: 10.3389/fimmu.2018.02133. eCollection 2018. PubMed PMID: 30294325; PubMed Central PMCID: PMC6158367.

30: Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ; From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium. Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle. 2018 Dec;9(6):1053-1062. doi: 10.1002/jcsm.12349. Epub 2018 Sep 29. PubMed PMID: 30269421; PubMed Central PMCID: PMC6240754.

31: Glueck B, Han Y, Cresci GAM. Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding. J Immunol Res. 2018 Aug 19;2018:9671919. doi: 10.1155/2018/9671919. eCollection 2018. PubMed PMID: 30211234; PubMed Central PMCID: PMC6120279.

32: Lee K, Haddad A, Osme A, Kim C, Borzou A, Ilchenko S, Allende D, Dasarathy S, McCullough A, Sadygov RG, Kasumov T. Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits. Mol Cell Proteomics. 2018 Dec;17(12):2371-2386. doi: 10.1074/mcp.RA118.000961. Epub 2018 Aug 31. PubMed PMID: 30171159; PubMed Central PMCID: PMC6283295.

33: European Association for the Study of the Liver. Electronic address:; European Association for the Study of the Liver. EASL Clinical Practice Guidelines on nutrition in chronic liver disease. J Hepatol. 2019 Jan;70(1):172-193. doi: 10.1016/j.jhep.2018.06.024. Epub 2018 Aug 23. PubMed PMID: 30144956; PubMed Central PMCID: PMC6657019.

34: Hajifathalian K, Torabi Sagvand B, McCullough AJ. Effect of Alcohol Consumption on Survival in Nonalcoholic Fatty Liver Disease: A National Prospective Cohort Study. Hepatology. 2019 Aug;70(2):511-521. doi: 10.1002/hep.30226. Epub 2018 Oct 2. PubMed PMID: 30125379; PubMed Central PMCID: PMC6380949.

35: Roberts AB, Gu X, Buffa JA, Hurd AG, Wang Z, Zhu W, Gupta N, Skye SM, Cody DB, Levison BS, Barrington WT, Russell MW, Reed JM, Duzan A, Lang JM, Fu X, Li L, Myers AJ, Rachakonda S, DiDonato JA, Brown JM, Gogonea V, Lusis AJ, Garcia-Garcia JC, Hazen SL. Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential. Nat Med. 2018 Sep;24(9):1407-1417. doi: 10.1038/s41591-018-0128-1. Epub 2018 Aug 6. PubMed PMID: 30082863; PubMed Central PMCID: PMC6129214.

36: Manterola A, Bernal-Chico A, Cipriani R, Canedo-Antelo M, Moreno-García Á, Martín-Fontecha M, Pérez-Cerdá F, Sánchez-Gómez MV, Ortega-Gutiérrez S, Brown JM, Hsu KL, Cravatt B, Matute C, Mato S. Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination. Biochem Pharmacol. 2018 Nov;157:189-201. doi: 10.1016/j.bcp.2018.07.042. Epub 2018 Aug 1. PubMed PMID: 30075103; PubMed Central PMCID: PMC6239900.

37: Kim Y, Gromovsky AD, Brown JM, Chung S. Gamma-tocotrienol attenuates the aberrant lipid mediator production in NLRP3 inflammasome-stimulated macrophages. J Nutr Biochem. 2018 Aug;58:169-177. doi: 10.1016/j.jnutbio.2018.05.007. Epub 2018 Jun 4. PubMed PMID: 29957361; PubMed Central PMCID: PMC6095813.

38: Wang J, Kainrad N, Shen H, Zhou Z, Rote P, Zhang Y, Nagy LE, Wu J, You M. Hepatic Knockdown of Splicing Regulator Slu7 Ameliorates Inflammation and Attenuates Liver Injury in Ethanol-Fed Mice. Am J Pathol. 2018 Aug;188(8):1807-1819. doi: 10.1016/j.ajpath.2018.05.004. Epub 2018 Jun 2. PubMed PMID: 29870742; PubMed Central PMCID: PMC6099363.

39: You M. Obesity and Binge Drinking: Two Hits Driving Liver Fibrosis Progression? Cell Mol Gastroenterol Hepatol. 2018 Feb 3;5(3):424-425. doi: 10.1016/j.jcmgh.2018.01.009. eCollection 2018 Mar. PubMed PMID: 29675457; PubMed Central PMCID: PMC5904035.

40: McCullough RL, McMullen MR, Sheehan MM, Poulsen KL, Roychowdhury S, Chiang DJ, Pritchard MT, Caballeria J, Nagy LE. Complement Factor D protects mice from ethanol-induced inflammation and liver injury. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G66-G79. doi: 10.1152/ajpgi.00334.2017. Epub 2018 Mar 29. PubMed PMID: 29597356; PubMed Central PMCID: PMC6109707.

41: Brown JM, Hazen SL. Microbial modulation of cardiovascular disease. Nat Rev Microbiol. 2018 Mar;16(3):171-181. doi: 10.1038/nrmicro.2017.149. Epub 2018 Jan 8. Review. PubMed PMID: 29307889; PubMed Central PMCID: PMC5885760.

42: Ding L, Zhang L, Biswas S, Schugar RC, Brown JM, Byzova T, Podrez E. Akt3 inhibits adipogenesis and protects from diet-induced obesity via WNK1/SGK1 signaling. JCI Insight. 2017 Nov 16;2(22). pii: 95687. doi: 10.1172/jci.insight.95687. eCollection 2017 Nov 16. PubMed PMID: 29202451; PubMed Central PMCID: PMC5752373.

43: Schugar RC, Willard B, Wang Z, Brown JM. Postprandial gut microbiota-driven choline metabolism links dietary cues to adipose tissue dysfunction. Adipocyte. 2018 Jan 2;7(1):49-56. doi: 10.1080/21623945.2017.1398295. Epub 2017 Nov 27. Review. PubMed PMID: 29172946; PubMed Central PMCID: PMC5915041.

44: Dasarathy S. Myostatin and beyond in cirrhosis: all roads lead to sarcopenia. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):864-869. doi: 10.1002/jcsm.12262. PubMed PMID: 29168629; PubMed Central PMCID: PMC5700432.

45: Saikia P, Roychowdhury S, Bellos D, Pollard KA, McMullen MR, McCullough RL, McCullough AJ, Gholam P, de la Motte C, Nagy LE. Hyaluronic acid 35 normalizes TLR4 signaling in Kupffer cells from ethanol-fed rats via regulation of microRNA291b and its target Tollip. Sci Rep. 2017 Nov 15;7(1):15671. doi: 10.1038/s41598-017-15760-4. PubMed PMID: 29142263; PubMed Central PMCID: PMC5688113.

46: Lindenmeyer CC, McCullough AJ. The Natural History of Nonalcoholic Fatty Liver Disease-An Evolving View. Clin Liver Dis. 2018 Feb;22(1):11-21. doi: 10.1016/j.cld.2017.08.003. Review. PubMed PMID: 29128051; PubMed Central PMCID: PMC6130315.

47: You M, Zhou Z, Daniels M, Jogasuria A. Endocrine Adiponectin-FGF15/19 Axis in Ethanol-Induced Inflammation and Alcoholic Liver Injury. Gene Expr. 2018 May 18;18(2):103-113. doi: 10.3727/105221617X15093738210295. Epub 2017 Nov 2. Review. PubMed PMID: 29096734; PubMed Central PMCID: PMC5953845.

48: Gromovsky AD, Schugar RC, Brown AL, Helsley RN, Burrows AC, Ferguson D, Zhang R, Sansbury BE, Lee RG, Morton RE, Allende DS, Parks JS, Spite M, Brown JM. Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):218-231. doi: 10.1161/ATVBAHA.117.309660. Epub 2017 Oct 26. PubMed PMID: 29074585; PubMed Central PMCID: PMC5746431.

49: Chen L, Chen R, Kemper S, Brigstock DR. Pathways of production and delivery of hepatocyte exosomes. J Cell Commun Signal. 2018 Mar;12(1):343-357. doi: 10.1007/s12079-017-0421-7. Epub 2017 Oct 23. PubMed PMID: 29063370; PubMed Central PMCID: PMC5842184.

50: Dasarathy S, Hatzoglou M. Hyperammonemia and proteostasis in cirrhosis. Curr Opin Clin Nutr Metab Care. 2018 Jan;21(1):30-36. doi: 10.1097/MCO.0000000000000426. Review. PubMed PMID: 29035972; PubMed Central PMCID: PMC5806198.

51: Brown AL, Mark Brown J. Critical roles for α/β hydrolase domain 5 (ABHD5)/comparative gene identification-58 (CGI-58) at the lipid droplet interface and beyond. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1233-1241. doi: 10.1016/j.bbalip.2017.07.016. Epub 2017 Aug 4. Review. PubMed PMID: 28827091; PubMed Central PMCID: PMC5672829.

52: Dasarathy J, Varghese R, Feldman A, Khiyami A, McCullough AJ, Dasarathy S. Patients with Nonalcoholic Fatty Liver Disease Have a Low Response Rate to Vitamin D Supplementation. J Nutr. 2017 Oct;147(10):1938-1946. doi: 10.3945/jn.117.254292. Epub 2017 Aug 16. PubMed PMID: 28814531; PubMed Central PMCID: PMC5610550.

53: Gliniak CM, Brown JM, Noy N. The retinol-binding protein receptor STRA6 regulates diurnal insulin responses. J Biol Chem. 2017 Sep 8;292(36):15080-15093. doi: 10.1074/jbc.M117.782334. Epub 2017 Jul 21. PubMed PMID: 28733465; PubMed Central PMCID: PMC5592683.

54: Marin V, Poulsen K, Odena G, McMullen MR, Altamirano J, Sancho-Bru P, Tiribelli C, Caballeria J, Rosso N, Bataller R, Nagy LE. Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients. J Hepatol. 2017 Nov;67(5):1018-1025. doi: 10.1016/j.jhep.2017.06.014. Epub 2017 Jun 22. PubMed PMID: 28647568; PubMed Central PMCID: PMC5650516.

55: Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Tang WHW, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown JM. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Rep. 2017 Jun 20;19(12):2451-2461. doi: 10.1016/j.celrep.2017.05.077. Erratum in: Cell Rep. 2017 Jul 5;20(1):279. PubMed  PMID: 28636934; PubMed Central PMCID: PMC5672822.

56: Dasarathy S. Are Exercise Benefits in Nonalcoholic Fatty Liver Disease Due to Increased Autophagy? Exerc Sport Sci Rev. 2017 Jul;45(3):125. doi: 10.1249/JES.0000000000000118. PubMed PMID: 28622190; PubMed Central PMCID: PMC5505627.

57: Dasarathy J, McCullough AJ, Dasarathy S. Sarcopenia in Alcoholic Liver Disease: Clinical and Molecular Advances. Alcohol Clin Exp Res. 2017 Aug;41(8):1419-1431. doi: 10.1111/acer.13425. Epub 2017 Jul 11. Review. PubMed PMID: 28557005; PubMed Central PMCID: PMC5553706.

58: Janssen AWF, Houben T, Katiraei S, Dijk W, Boutens L, van der Bolt N, Wang Z, Brown JM, Hazen SL, Mandard S, Shiri-Sverdlov R, Kuipers F, Willems van Dijk K, Vervoort J, Stienstra R, Hooiveld GJEJ, Kersten S. Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids. J Lipid Res. 2017 Jul;58(7):1399-1416. doi: 10.1194/jlr.M075713. Epub 2017 May 22. PubMed PMID: 28533304; PubMed Central PMCID: PMC5496037.

59: Brown JM, Hazen SL. Targeting of microbe-derived metabolites to improve human health: The next frontier for drug discovery. J Biol Chem. 2017 May 26;292(21):8560-8568. doi: 10.1074/jbc.R116.765388. Epub 2017 Apr 7. Review. PubMed PMID: 28389555; PubMed Central PMCID: PMC5448085.

60: Dasarathy S, Brown JM. Alcoholic Liver Disease on the Rise: Interorgan Cross Talk Driving Liver Injury. Alcohol Clin Exp Res. 2017 May;41(5):880-882. doi: 10.1111/acer.13370. Epub 2017 Apr 10. Review. PubMed PMID: 28295407; PubMed Central PMCID: PMC5405002.

61: Saikia P, Bellos D, McMullen MR, Pollard KA, de la Motte C, Nagy LE. MicroRNA 181b-3p and its target importin α5 regulate toll-like receptor 4 signaling in Kupffer cells and liver injury in mice in response to ethanol. Hepatology. 2017 Aug;66(2):602-615. doi: 10.1002/hep.29144. Epub 2017 Jul 4. PubMed PMID: 28257601; PubMed Central PMCID: PMC5519440.

62: Kumar A, Davuluri G, Silva RNE, Engelen MPKJ, Ten Have GAM, Prayson R, Deutz NEP, Dasarathy S. Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. Hepatology. 2017 Jun;65(6):2045-2058. doi: 10.1002/hep.29107. Epub 2017 Apr 28. PubMed PMID: 28195332; PubMed Central PMCID: PMC5444955.

63: Zhou H, Yu M, Roychowdhury S, Sanz-Garcia C, Pollard KA, McMullen MR, Liu X, Li X, Nagy LE. Myeloid-MyD88 Contributes to Ethanol-Induced Liver Injury in Mice Linking Hepatocellular Death to Inflammation. Alcohol Clin Exp Res. 2017 Apr;41(4):719-726. doi: 10.1111/acer.13345. Epub 2017 Mar 10. PubMed PMID: 28165624; PubMed Central PMCID: PMC5391031.

64: Wegner SA, Pollard KA, Kharazia V, Darevsky D, Perez L, Roychowdhury S, Xu A, Ron D, Nagy LE, Hopf FW. Limited Excessive Voluntary Alcohol Drinking Leads to Liver Dysfunction in Mice. Alcohol Clin Exp Res. 2017 Feb;41(2):345-358. doi: 10.1111/acer.13303. Epub 2017 Jan 19. PubMed PMID: 28103636; PubMed Central PMCID: PMC5636002.

65: Cresci GA, Glueck B, McMullen MR, Xin W, Allende D, Nagy LE. Prophylactic tributyrin treatment mitigates chronic-binge ethanol-induced intestinal barrier and liver injury. J Gastroenterol Hepatol. 2017 Sep;32(9):1587-1597. doi: 10.1111/jgh.13731. PubMed PMID: 28087985; PubMed Central PMCID: PMC5511097.

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