Inflammation and Immunity : Careers

Research in the Department of Inflammation and Immunity considers how the immune system may cause certain diseases and how it may be used to treat others. Our work addresses both basic mechanisms and clinical objectives.




Postdoctoral 4

Date Contact Description
03/12/2019 Amy Lightner, MD
lightna@ccf.org

Immediate opening for a project scientist position in the Lightner Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and knowledge of techniques in regenerative medicine, with expertise in mesenchymal stem cell culture, extracellular/exesome extraction, murine models of colitis/Crohn’s disease are encouraged to apply.

Must be familiar with cultivation of multiple cell lines, Western blotting, and RNA based methods including quantitative PCR and Northern blotting, lenti- retro- and adenoviral systems of shRNA delivery, expression of exogenous proteins, and the Casp9/Crispr system. Experience in murine cell delivery and organ isolation is an advantage. Excellent writing skills are essential. The successful candidate will be expected to design, implement and manage research projects addressing regenerative medicine products for the treatment of human disease, namely in inflammatory bowel disease.  The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter, CV and contact information for 3 references to:

Amy Lightner, MD, lightna@ccf.org 

02/26/2019 Brian Gastman, MD
gastmab@ccf.org

Immediate opening for a Postdoctoral Fellow position in the Gastman Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and knowledge of techniques in immunology, molecular biology and biochemistry, and with expertise in cell, animal, or human models of cancer, and specifically cancer immunity are encouraged to apply. 

Must be familiar with immunologic assays (FACS, cytotoxicity, mouse tumor models, etc..), cultivation of multiple cell lines, Western blotting, and RNA based methods including quantitative PCR and Northern blotting,  expression of exogenous proteins, and the Casp9/Crispr system.    Experience with in vivo murine models is also important.  Excellent writing skills are essential. The successful candidate will be expected to design, implement and manage research projects addressing the role of suppressor cells in the tumor microenvironment.  The applicant will have significant exposure to human specimens from a multitude of research protocols and clinical trials.  The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Our laboratory is highly collaborative and works closely with industry.  The prospective applicant would be expected to not only be involved in high level research, but also to act as an ambassador between our lab and our industry partners.  Thus, proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Brian Gastman, MD.; Department of Inflammation & Immunity; Lerner Research Institute / NE4-303; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445-6950; gastmab@ccf.org

01/18/2019 Laura Nagy
nagyL3@ccf.org

A postdoctoral fellow position is available immediately in the laboratory of Dr. Laura Nagy in the Department of Inflammation and Immunity to study the effects of ethanol on the innate immune system, including toll-like receptor signal transduction and complement activation.  The research will focus on the effects of chronic ethanol on key signal transduction pathways in hepatic macrophages with a goal towards understanding the mechanism of development of chronic inflammatory responses in liver.  Projects related to miRNA regulation of cytokine expression, mechanisms of cell death and pathways of gut-liver or adipose-liver interactions are available. 

Experience in at least one of the following areas is desired:  cell biology, signal transduction, molecular biology, intestinal physiology, bioinformatics or macrophage biology. Experience in experimental design and data analysis in both cultured cells and animal models is preferred.  Strong written and oral communication skills are required.

Candidates should have a recent PhD in cell biology, immunology, biochemistry, or a related discipline and experience in signal transduction and cell biology. 

Interested applicants please submit a CV and names and contact information for three references to Dr. Laura Nagy, Department of Inflammation and Immunity (NE40) at Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland OH 44195 or via email to nagyL3@ccf.org

01/16/2019 Vidula Vachharajani, MD
vachhav@ccf.org

Immediate opening for a Postdoctoral Fellow position in the Vachharajani Laboratory in the Department of Inflammation & Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and knowledge of techniques in molecular biology and biochemistry, and with expertise in cell, animal, or human models of diabetes and obesity are encouraged to apply.

Must be familiar with cultivation of multiple cell lines, Western blotting, and RNA based methods including quantitative PCR and Northern blotting, lenti- retro- and adenoviral systems of shRNA delivery, expression of exogenous proteins, and the Casp9/Crispr system. Experience in murine peritoneal macrophage isolation and analysis is an advantage. Excellent writing skills are essential. The successful candidate will be expected to design, implement and manage research projects addressing inflammatory and metabolic changes during diet induced obesity with sepsi.  The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Vidula Vachharajani, MD; Department of Inflammation & Immunity; Lerner Research Institute / NC22; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445-7191, vachhav@ccf.org



Technical & Adminstrative

Applications for technical research positions and administrative positions at the Lerner Research Institute can be submitted on the Cleveland Clinic jobs web site.