The Department of Inflammation & Immunity advances scientific understanding by bringing together a dedicated and collaborative team of scientists at the forefront of immunologic and organ-based research, to deliver impactful translational science that improves the health and well-being of patients at Cleveland Clinic and across the globe.

Working side-by-side with physicians to study patients and diseases, Inflammation & Immunity scientists address challenging questions to uncover the root causes of inflammatory diseases, and ultimately translate these discoveries into new diagnostic testing, therapies and preventive measures for patients.

Department News


Cleveland Clinic Study Finds No Association Between Influenza Vaccine and COVID-19 Risk

Using patient data from Cleveland Clinic’s COVID-19 registry, Dr. Zein found that receiving the flu vaccine does not increase risk for COVID-19 or worsen associated disease outcomes, suggesting it is safe and advisable to receive the influenza vaccine this flu season.

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$2.6M Grant Awarded by NIH to Identify Possible Targets for Treating Alcohol-Related Organ Damage

Dr. Cresci will explore how increasing levels of two molecules commonly depleted as a result of chronic alcohol exposure may help to rescue pathologies of alcohol use disorder, including bacterial imbalances, leaky gut and increased circulating toxins.

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Department of Defense Funds Research for Potential New Drug to Treat Obesity and Pre-Diabetes

Investigating inter-organ cross-talk between the gut and immune system, Drs. de la Motte and Nagy will test HA35 as potential therapeutic for Western diet-induced metabolic syndrome.

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