Lerner Research Institute

Home to basic, translational and clinical research at Cleveland Clinic,
a top U.S. hospital.



NIH Grant to Advance the Study of Chronic Kidney Disease in African Americans

Drs. Bruggeman, Sedor and O’Toole will investigate the pathogenic mechanisms of chronic kidney disease to develop greater understanding of genetic susceptibility and develop new treatment strategies.

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Researchers Investigate Sex Differences in Systemic Lupus Erythematosus

Dr. Jorgensen and team have uncovered the role of S100a9 as a molecule integral in determining sex-specific immune responses in lupus.

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Failed Alzheimer’s Drug May Hold Promise for Treating Glioblastoma

Dr. Bao’s team found that treating preclinical models of glioblastoma with verubecestat, a BACE1-inhibiting drug, reduces cancer progression by targeting a class of immune cells abundant in tumors.

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Institute News

New Global Center for Pathogen and Human Health Research

The Global Center for Pathogen and Human Health Research will bring together a research team to broaden understanding of viral pathogens and the human immune response toward preparing and protecting against future public health threats.


Accelerating Discoveries to Patients

Working together with Cleveland Clinic physicians, our scientists are discovering the treatments of tomorrow. While many spend their days working at the laboratory bench, their inspiration can be found at the patient bedside.

Education & Training

Postdoctoral Program

Train on the cutting-edge of research and join our thriving postdoc association.

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Molecular Medicine PhD Program

Earn your PhD through our unique program that combines basic science and medical knowledge.

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Graduate Programs

Earn your PhD through our joint program with local universities.

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