Lerner Research Institute

Home to basic, translational and clinical research at Cleveland Clinic,
a top U.S. hospital.



Researchers Find Potential for Repurposing Drug to Target Certain Types of Leukemia Cells

Drs. Jha and Maciejewski have identified eltrombopag as a potent inhibitor of specific leukemia cells, which could lead to new drugs that target leukemia cells while preserving and expanding normal blood cells.

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Flipping the Switch on Prostate Cancer Immunotherapy

Dr. Nima Sharifi and a team of researchers uncovered how tumors circumvent prostate cancer therapy and identified a potential window of time after treatment when tumors may be responsive to immunotherapy.

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Exploring a Blood-Based Biomarker of Inflammation for Alzheimer’s Disease

Dr. Bekris’ team found that patterns of sTREM2-related inflammatory activity were specific to Alzheimer’s disease stages.

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Institute News

New Global Center for Pathogen and Human Health Research

The Global Center for Pathogen and Human Health Research will bring together a research team to broaden understanding of viral pathogens and the human immune response toward preparing and protecting against future public health threats.


Accelerating Discoveries to Patients

Working together with Cleveland Clinic physicians, our scientists are discovering the treatments of tomorrow. While many spend their days working at the laboratory bench, their inspiration can be found at the patient bedside.

Education & Training

Postdoctoral Program

Train on the cutting-edge of research and join our thriving postdoc association.

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Molecular Medicine PhD Program

Earn your PhD through our unique program that combines basic science and medical knowledge.

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Graduate Programs

Earn your PhD through our joint program with local universities.

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