Lerner Research Institute

Home to basic, translational and clinical research at Cleveland Clinic, a top U.S. hospital.

News

New Analysis Shows Surgery for Drug-Resistant Temporal Lobe Epilepsy is Cost-Effective
08/03/2020

The first U.S. cost-effectiveness analysis in decades supports more surgical evaluations, suggesting the up-front cost of evaluation is significantly smaller than the price paid by patients, society and healthcare systems when medications alone are used.

Potential New Drug Target for Steroid-Resistant Inflammatory Diseases Uncovered
07/27/2020

Dr. Min and colleagues uncovered a key contribution of regulatory T cells during glucocorticoid-mediated treatment of inflammation, elucidating a possible new, related target for treating aggressive inflammatory diseases.

Research Reveals Potential Drug Target for Treating Obesity and Other Metabolic Conditions
07/23/2020

Dr. Wu and his team show that targeting the protein hepsin may be a viable option for treating diabetes and other diseases, finding that inhibiting its expression prevented or reduced obesity and diabetes severity in preclinical models.

Institute News

COVID-19: Our Response

The best and brightest scientists, researchers and clinicians are working together to study treatments and prevention strategies to overcome the novel coronavirus (SARS-CoV-2) causing COVID-19. Explore our latest research news and discoveries.

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Accelerating Discoveries to Patients

Working together with Cleveland Clinic physicians, our scientists are discovering the treatments of tomorrow. While many spend their days working at the laboratory bench, their inspiration can be found at the patient bedside.