Lerner Research Institute

Home to basic, translational and clinical research at Cleveland Clinic, a top U.S. hospital.



Study Links Gene Variant with Alzheimer’s Disease Resilience

Dr. Bekris’ team has found that Alzheimer’s disease resilience may be modulated by interactions between a TNFRSF1B gene variant and the protein sTNFR2.

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New Analysis of Previous Trial Results Offers Insights into Personalized Care for Type 2 Diabetes

Dr. Rotroff and team found that genetic variation may help to identify diabetes patients at risk for cardiovascular disease who may benefit from aggressive glycemia treatment.

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Researchers to Study Genetics of Focal Cortical Dysplasia with New NIH Grant

Dr. Lal’s team will perform the most comprehensive genetic analysis of focal cortical dysplasia (FCD) to confirm proposed FCD-associated genes and identify novel FCD causal genes and variants.

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Institute News

New Global Center for Pathogen Research & Human Health

The Global Center for Pathogen Research & Human Health will bring together a research team to broaden understanding of viral pathogens and the human immune response toward preparing and protecting against future public health threats.


COVID-19: Our Response

The best and brightest scientists, researchers and clinicians are working together to study treatments and prevention strategies to overcome the novel coronavirus (SARS-CoV-2) causing COVID-19. Explore our latest research news and discoveries.

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Accelerating Discoveries to Patients

Working together with Cleveland Clinic physicians, our scientists are discovering the treatments of tomorrow. While many spend their days working at the laboratory bench, their inspiration can be found at the patient bedside.

Education & Training

Postdoctoral Program

Train on the cutting-edge of research and join our thriving postdoc association.

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Molecular Medicine PhD Program

Earn your PhD through our unique program that combines basic science and medical knowledge.

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Graduate Programs

Earn your PhD through our joint program with local universities.

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