Lerner Research Institute

Home to basic, translational and clinical research at Cleveland Clinic, a top U.S. hospital.



Uncovering the Link between the Gut and Autoimmunity in Patients with PTEN Hamartoma Tumor Syndrome

A pilot study led by Dr. Eng suggests that the gut microbiome may contribute to the development of autoimmune diseases and immune dysregulation in patients with PTEN hamartoma tumor syndrome.

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Characterizing Patient Immune Responses to Emerging Tick-borne Virus

Using patient samples, Dr. Jung and his team uncovered inflammatory biomarkers associated with severe disease and death caused by SFTSV infection, and identified the critical role B cells play in infection.

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Nanoparticle-delivered COVID-19 Vaccine Candidate Shows Promise in Preclinical Studies

Dr. Jung and his team have developed a vaccine candidate that targets the primary binding site between SARS-Cov-2 and human cells, which universally produced neutralizing antibodies and prevented infection in preclinical models.

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Institute News

New Global Center for Pathogen Research & Human Health

The Global Center for Pathogen Research & Human Health will bring together a research team to broaden understanding of viral pathogens and the human immune response toward preparing and protecting against future public health threats.


COVID-19: Our Response

The best and brightest scientists, researchers and clinicians are working together to study treatments and prevention strategies to overcome the novel coronavirus (SARS-CoV-2) causing COVID-19. Explore our latest research news and discoveries.

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Accelerating Discoveries to Patients

Working together with Cleveland Clinic physicians, our scientists are discovering the treatments of tomorrow. While many spend their days working at the laboratory bench, their inspiration can be found at the patient bedside.

Education & Training

Postdoctoral Program

Train on the cutting-edge of research and join our thriving postdoc association.

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Molecular Medicine PhD Program

Earn your PhD through our unique program that combines basic science and medical knowledge.

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Graduate Programs

Earn your PhD through our joint program with local universities.

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