Research Associate/Project Staff Positions

Job Description:

Apply on Cleveland Clinic's career website.

The Lou Ruvo Center for Brain Health (LRCBH) at Cleveland Clinic Nevada is accepting applications for a doctoral-level brain imaging researcher to join the LRCBH professional staff and support multiple neuroimaging studies examining biomarkers of brain aging and dementia. The LRCBH is a highly productive and growing Center, with key areas of interest in healthy aging, Alzheimer’s disease and related dementias, neurodegenerative movement disorders, and multiple sclerosis.

This position will be responsible for organizing and managing brain imaging research data, including post-processing, data manipulation, quality assurance, and data analysis, as well as working with existing data teams to create, maintain, and update researchimaging databases. Current large datasets include an NIA-funded exploratory Alzheimer’s Disease Research Center and an NIGMS-funded Center for Biomedical Research Excellence, as well as internal investigator-initiated imaging research. Support for these projects, and collaboration with other LRCBH staff on grant applications and manuscript preparations, are expected.

Competitive candidates will have experience collaborating in an academic health care setting, with examples of creative analytic approaches to complex problems in brain health and aging through proven records of collaborative publications and/or grantsmanship. A basic understanding of neurodegenerative diseases and their impact on human aging is essential for success in this role.

Candidates must have excellent written and verbal skills with the ability and desire to conduct collaborative clinical and methodologic research. Successful candidates should also demonstrate an interest in developing an independent research portfolio that advances the science of brain aging and neurodegenerative imaging.

Opportunities for academic appointments are available and will be commensurate with experience of the candidate.

Job Requirements

• Doctoral degree in neurology, psychiatry, neuroscience, cognitive science, or a related discipline
• Experience in magnetic resonance imaging (MRI) is required, including (but not limited to) MRI, fMRI, diffusion tensor imaging, MR spectroscopy
• Ability to work with other imaging modalities (e.g., positron emission tomography, single photon emission computerized tomography) will be highly valued
• Demonstrated success with large, longitudinal, imaging databases with clinically relevant populations and/or patient-reported clinical, cognitive, biomarker, outcomes, or related data is required
• Experience as a consultant and/or project leader supporting large multidisciplinary, collaborative research initiatives
• Experience supervising and managing teams, including trainees, is highly desired

Apply on Cleveland Clinic's career website.

Contact:

Alex Riegelsberger
riegela3@ccf.org

Job Description:

Biological Safety Officer - Florida Research & Innovation Center

Cleveland Clinic Florida Research and Innovation Center (FRIC) is seeking a Biological Safety Officer who can be part of a dynamic and rapidly growing organization. The candidate will oversee the biosafety program, ensure compliance with applicable rules and requirements, and use data to develop corrective and preventative practices and procedures related to biosafety.  In addition, the candidate will serve as an expert resource and the implementation, management, and improvement of the Select Agent Program. 

As one of the world’s largest and busiest health centers, Cleveland Clinic is committed to delivering high quality programs of patient care, research, and education. Cleveland Clinic’s Lerner Research Institute (LRI) researchers are at the forefront of biological discovery with research related to cancer, cardiovascular and metabolic diseases, brain and eye diseases, and diseases of inflammation and immune systems. With more than 1,500 researchers and support personnel in 190 laboratories across 11 departments and multiple centers, the Lerner Research Institute is one of the largest research institutes in the nation, consistently ranking in the top 10 in National Institutes of Health funding, a benchmark of research success. 

Additionally, the Lerner Research Institute has recently opened Cleveland Clinic Florida Research and Innovation Center (FRIC) which is dedicated to the discovery and advancement of innovative translational research, focused on immuno-oncology and infectious diseases.  The building is 3 floors with approximately 100,000 sq. ft. of dedicated research and support spaces. The FRIC is developing state of the art Shared Resource Laboratories in Flow Cytometry, Imaging, Bioinformatics, Select Agents and a Vivarium. 

As a Biological Safety Officer, your responsibilities will be to:

• Develop, implement, and direct a comprehensive biosafety program for the health system
• Ensure organizational compliance with regulatory and sponsor requirements associated with biosafety
• Supervise Cleveland Clinic biosafety professionals
• Serve as a member of the Institutional Biosafety Committee (IBC) and assist the IBC Chair by interacting with investigators whose work is under review by committee, reviewing research protocols to ensure adequate biosafety measures are included, providing guidance to IBC on containment issues, implementing IBC-approved policies and plans, and providing administrative support
• Maintain in-depth knowledge of biosafety principles and best practices and serve as a resource on related federal and state regulations
• Provide technical guidance to caregivers regarding equipment, facilities and work practices for protection of personnel, laboratories and environment from biological hazards
• Review experimental design, study protocols, procedures, and conduct risk assessments for research grant applications, material transfer agreements, research contracts, and research activities involving biohazardous agents and materials. These agents and materials may include recombinant or synthetic nucleic acid (rsNA), infectious agents, toxins, human-derived and nonhuman-derived materials, and human gene transfer clinical trials to ensure safe practices in support of the health system’s IBC, Institutional Animal Care and Use Committee (IACUC), and Institutional Review Board (IRB)
• Ensure facility compliance with regulations and guidelines pertaining to use, handling, shipping, and disposal of potential biohazards and rsNA
• Investigate accidents in regards to Biosafety issues and develop corrective action plans
• Assist with investigations and reporting of non-compliance
• Develop and implement emergency response procedures for incidents involving biohazardous agents and materials

Qualifications
Education

• A Master of Science or Ph.D. in biological science (i.e., microbiology, bacteriology, virology etc.) or related field

Work Experience

• Minimum 5 years experience in a biomedical research laboratory or related combination of education and experience. Experience in microbiology research is preferred.
• Minimum 5 years experience in the field of biological safety in a biomedical research facility
• Knowledge of NIH Guidelines, NIH/CDC BMBL guidelines, USG Policy for DURC, import and export programs (e.g. CDC IPP, APHIS, Bureau of Industry and Security), OSHA, and granting agency requirements
• Experience working in or supervising BSL-3 containment research
• Experience working with select agents or managing select agent research is preferred

Certifications

• Certification or eligibility for certification by American Biosafety Association (ABSA) as a Registered Biosafety Professional or Certified Biological Safety Professional is preferred

Other requirements

• Must achieve Department of Justice (DOJ) Security Risk Assessment (SRA) approval for working with select agents
• Must obtain/maintain annual medical clearance through Cleveland Clinic’s Occupational Health Department to work in a BSL-3 Environment 

Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities. Smoke/drug free environment.

Contact:

Sara Tavakoli
tavakos@ccf.org