The mission of the Department of Cancer Biology is to build bridges and teams to drive the best ideas in basic and translational cancer biology and developmental therapeutics to achieve breakthrough advances in the prevention, treatment and cure of cancer.
The department faculty are international leaders in brain, colorectal and prostate cancers, leukemia and myeloma, as well as cancer stem cells, mechanisms of DNA damage and repair, and fundamental molecular and cellular processes that impact microbial infections and cancer. Identifying the molecular mechanisms involved in the development and progression of human cancers as well as in normal cellular regulatory processes is our goal, enabling us to achieve our long-term objective of rapidly translating research into strategies that improve patient outcomes.
The Jae Jung lab studies virus-induced cancers and the mechanisms of and treatments for pathogens that cause human disease.Learn More
The George Stark lab studies the complex cell signaling mechanisms underlying innate immunity and cancer.Learn More
The Hannelore Heemers lab explores drug targets for novel, prostate cancer-selective forms of androgen deprivation therapy.Learn More
Breast cancer often relies on characteristics of healthy breast cell development, and the developmental regulator TLE3 could play a role in suppressing the spread of breast tumors.
The clinical trial strategy was developed through research on a gene associated with treatment-resistant prostate cancer, HSD3B1, and is in clinical trials at nine sites across the U.S.
Cleveland Clinic research into anti-viral immunity identified a novel mechanism in necroptosis, a form of programmed cell death.
Exciting investigation and groundbreaking discovery happens every day at Cleveland Clinic. Join our team of expert researchers at the Department of Cancer Biology.View Careers