Since Cleveland Clinic’s founding in 1921, research and innovation have been integral parts of the enterprise mission. Not only did the founders believe it was important to treat disease, but also to investigate the causes of disease. Nearly 100 years later, Cleveland Clinic Lerner Research Institute is at the forefront of biological discovery, conducting basic, translational and clinical research related to cancer, cardiovascular and metabolic diseases, brain and eye diseases, and diseases of the inflammation and immune systems. Our mission is to uncover the biological pathways of disease; develop new medical devices, diagnostic and treatment therapies, and cures; and train the next generation of biomedical researchers.

The Lerner emphasizes translational research that has the potential to improve patient care. Our scientists work closely with Cleveland Clinic physicians to transform groundbreaking discoveries made in the laboratory to the bedside. Our collaborative Research Centers of Excellence bring together scientific and clinical experts to solve problems seen in patients and accelerate discoveries into new treatments and cures.

With nearly 1,400 researchers and support personnel in 180 laboratories across 12 departments, the Lerner is one of the largest research institutes in the nation, consistently ranking in the top 10 in National Institutes of Health funding, a benchmark of research success. View our 2017 outcomes to learn more about our funding, productivity and collaborations.

In addition to conducting leading-edge research, we are also committed to training the next generation of young scientists. The Lerner offers joint programs with nearby universities and our own Molecular Medicine PhD program.