Postdoctoral 5

Date Contact Description
08/15/2018 Florian Rieder, M.D.
riederf@ccf.org

We have an opening for a Postdoctoral Fellow position in the Dr. Florian Rieder Laboratory in the Department of Inflammation & Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and interest in studying intestinal inflammation and fibrosis and cell to extracellular matrix interactions are encouraged to apply.

A highly motivated candidate will join a productive research team to participate in NIH and industry funded projects focusing on the roles of the extracellular matrix and cell to matrix interactions during tissue inflammation and fibrosis of the intestine. The candidate should have a publication record demonstrating on-hand molecular biology and cell biology expertise.

The candidate should furthermore be familiar with primary human cell culture, Western blotting, and RNA based methods including quantitative PCR and reporter assays, immunohistochemistry and mouse models of gut inflammation. Excellent communication skills in English are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Dr. Florian Rieder; Department of Pathobiology; Lerner Research Institute / NC22; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445 7156; E-mail: riederf@ccf.org.

07/25/2018 Brian Gastman, M.D.
gastmanb@ccf.org

Postdoctoral Fellow or Research Associate– Tumor immunology and immunotherapeutics.

Immediate opening for a Postdoctoral Fellow position in the Gastman Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and knowledge of techniques in immunology, molecular biology and biochemistry, and with expertise in cell, animal, or human models of cancer, and specifically cancer immunity are encouraged to apply. 

Must be familiar with immunologic assays (FACS, cytotoxicity, mouse tumor models, etc..), cultivation of multiple cell lines, Western blotting, and RNA based methods including quantitative PCR and Northern blotting,  expression of exogenous proteins, and the Casp9/Crispr system.    Experience with in vivo murine models is also important.  Excellent writing skills are essential. The successful candidate will be expected to design, implement and manage research projects addressing the role of suppressor cells in the tumor microenvironment.  The applicant will have significant exposure to human specimens from a multitude of research protocols and clinical trials.  The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Our laboratory is highly collaborative and works closely with industry.  The prospective applicant would be expected to not only be involved in high level research, but also to act as an ambassador between our lab and our industry partners.  Thus, proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Brian Gastman, MD.; Department of Inflammation & Immunity; Lerner Research Institute / NE4-303; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445-6950; gastmab@ccf.org

06/06/2018 Dr. Gail Cresci
dr. gail cresci

We have an opening for a Postdoctoral Research Fellow position in the Dr. Gail Cresci Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic.  Individuals with experience and interest in studying gut microbiome and metabolome on intestinal inflammation and immunity are encouraged to apply.  

A highly motivated candidate will join a productive research team to participate in NIH and industry funded projects focusing on the roles of altered intestinal microbiome and metabolome during antibiotic and pathogen exposure.  The candidate should have a publication record demonstrating hands-on microbiology, molecular biology and cell biology expertise. 

The candidate should furthermore be familiar with primary human cell culture, Western blotting, and RNA based methods including quantitative PCR and reporter assays, immunohistochemistry and mouse models of gut inflammation. Excellent communication skills in English are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship. 

A recent (or close to obtaining) Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Dr. Gail Cresci; Department of Inflammation and Immunity; Lerner Research Institute / NB2; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445 0874; E-mail: crescig@ccf.org.

 

 

04/17/2018 Laura Nagy
nagyl3@ccf.org

A Postdoctoral Fellow position is available in the Cleveland Clinic in the laboratory of Dr. Laura Nagy in the Department of Inflammation and Immunity to study the effects of ethanol on the innate immune system, including toll-like receptor signal transduction and complement activation.  The research will focus on the effects of chronic ethanol on key signal transduction pathways in hepatic innate immune cells (macrophages, infiltrating monocytes, neutrophils, etc) with a goal towards understanding the mechanism of development of chronic inflammatory responses in liverin order to develop rationale therapeutic interventions.  Our recent work using next generation sequencing of miRNA indicates that ethanol targets multiple levels in the regulation of cytokine expression leading to the development of alcoholic liver disease. We are also interested in identifying biomarkersand genetic risk factors for disease severity in a cohort of patients with alcoholic liver disease.

Experience in at least one of the following areas is desired:  cell biology, signal transduction, molecular biology, bioinformatics or macrophage biology. Experience in experimental design and data analysis in both cultured cells and animal models is preferred.  Strong written and oral communication skills are required.

Candidates should have a recent PhD in cell biology, immunology, biochemistry, or a related discipline and experience in signal transduction and cell biology. 

Interested applicants please submit a CV and names and contact information for three references to Dr. Laura Nagy, Department of Inflammation and Immunity (NE40) at Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland OH 44195 or via email to nagyL3@ccf.org

03/27/2018 Srinivasan Dasarathy MD
dasaras@ccf.org

We have an immediate opening for a Postdoctoral Fellow position in the Dr. Dasarathy Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and interest in studying signal transduction during metabolic perturbations are encouraged to apply. The laboratory focus is on using integrated molecular metabolic approaches in a comprehensive array of cellular, mouse, and human models.

A highly motivated candidate will join a productive research team to participate in NIH funded projects focusing on the molecular mechanisms of skeletal muscle loss and metabolic perturbations in disease. The candidate should have a publication record demonstrating on-hand molecular biology and cell biology expertise.

Must be familiar with mesenchymal cell culture (preferably skeletal muscle), Western blotting, and RNA based methods including quantitative PCR and reporter assays, subcloning between different vectors, lenti- retro- and adenoviral systems for cDNA and shRNA delivery. Preference will be given to candidates with previous experience in skeletal muscle biology, CRISPR/Cas9-dependent gene editing, confocal microscopy/cell imaging or mouse models of muscle loss. Excellent communication skills in English are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Dr. Srinivasan Dasarathy; Department of Pathobiology; Lerner Research Institute / NE4 208; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 636-0096; E-mail: dasaras@ccf.org.



Technical & Adminstrative

Applications for technical research positions and administrative positions at the Lerner Research Institute can be submitted on the Cleveland Clinic jobs web site.