Saurav Misra, Ph.D. Assistant Staff Department of Molecular Cardiology Lerner Research Institute / NB50 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 444- 2054 Fax: (216) 444-9263 misras@ccf.org

Area of General Research Interest:

X-ray crystallography; Structure determination of proteins involved in intracellular trafficking and signaling, specifically in the areas of 1) lipid signaling, 2) regulation by ubiquitination, 3) the innate immune response. Structural and biophysical investigation of the protein-protein interactions in these signal transduction cascades.

Investigators:

• Jin, Cheng, Research Technologist
• Page, Richard, Ph.D., Postdoctoral Fellow
• Xu, Zhen, Ph.D., Research Associate

Collaborators:

• Jun Qin, Ph.D. (Molecular Cardiology, CC)
• Xiaoxia Li, Ph.D. (Immunology, CC)
• Robert Fuller, Ph.D. (Dept. of Biological Chemistry, University of Michigan)
• Ganes Sen, Ph.D. (Molecular Genetics, CC)
• Wen Li (Graduate Student, Biochemistry Department, CWRU) 
• Thomas Weimbs (Dept. of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara)
• Sandra Bajjalieh (Dept. of Pharmacology, Univ. of Washington)

Links:

• Cleveland Center for Structural Biology