Saurav Misra, Ph.D. Associate Staff Department of Molecular Cardiology Lerner Research Institute / NB50 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 444- 2054 Fax: (216) 444-9263 misras@ccf.org

Area of General Research Interest:

Our research is currently focused on using X-ray crystallography, NMR, protein-protein interaction assays and other biochemical techniques to characterize:
1) Chaperones and cochaperones, especially the Hsp70 nucleotide exchange factor Bag2; 2) proteins involved in ubiquitination, including the quality control ubiquitin ligase CHIP and the Act1 ubiquitin ligase, which functions in innate immune signaling; 3) cytoskeletal and adaptor proteins that regulate the Cystic Fibrosis protein CFTR

Investigators:

• Amick, Joseph, B.A., Research Technician
• Page, Richard, Ph.D., Postdoctoral Fellow

Collaborators:

• Jun Qin, Ph.D. (Molecular Cardiology, CC)
• Xiaoxia Li, Ph.D. (Immunology, CC)

Links:

• Cleveland Center for Membrane and Structural Biology
• Dr. Misra's Public Lab Wiki