
Marinis J.M., Homer C.R., McDonald C., & Abbott D.W. (2011) A novel motif in the Crohn’s disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses. J. Biol. Chem. 286:1938-50. Epub 2010 Nov 19, PMCID: PMC3023490 [Available on 2012/1/21].
Homer C.R., Richmond A.L., Rebert N.A., Achkar J.-P., & McDonald C. (2010) ATG16L1 and NOD2 interact in an autophagy-dependent, anti-bacterial pathway implicated in Crohn’s disease pathogenesis. Gastroenterology 139:1630-1641.![]()
Marina-García N., Franchi L., Kim Y.-G., Miller D., McDonald C. , Boons G.-J., & Nuñez G. (2008) Pannexin-1-Mediated Intracellular Delivery of Muramyl Dipeptide Induces Caspase-1 Activation via Cryopyrin/NLRP3 Independently of Nod2. J. Immunol. 180: 4050-4057. ![]()
Lécine P., Esmiol S., Métais J.-Y., Nicoletti C., Nourry C., McDonald C. , Nuñez G., Hugot J.-P., Borg J.-P., & Ollendorff V. (2007) The Nod2-Rick Complex Signals from the Plasma Membrane. J. Biol. Chem. 282:15197-15207. ![]()
Park J.-H., Kim Y.-G., McDonald C. , Kanneganti T.-D., Body-Malapel M., Inohara N., & Nuñez G. (2007) RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but not TLRs. J. Immunol. 178:2380-2386. ![]()
Coussens N.P., Mowers J. C., McDonald C. , Nuñez G. & Ramaswamy S. (2007) Crystal Structure of the Nod1 Caspase Activation and Recruitment Domain. Biochem. Biophys. Res. Comm. 353:1-5. ![]()
Franchi L., McDonald C. , Kanneganti T.-D., Amer A., & Núñez G. (2006) NLRs:Intracellular Pattern Recognition Receptors for Pathogen Detection and Host Defense, J. Immunol. 177:3507-13. ![]()
McDonald C. , Chen F.F., Ollendorff V., Ogura Y., Marchetto S., Lécine P., Borg J.-P. & Nuñez G. (2005) A role for Erbin as a regulator of Nod2-dependent NF-kB signaling. J. Biol. Chem. 280:40301-40309. ![]()
McDonald C. , Inohara N. & Nuñez G. (2005) Peptidoglycan signaling in innate immunity and inflammatory disease. Review J. Biol. Chem. 280:20177-80. ![]()
Inohara N., Chamaillard M., McDonald C. & Nuñez G. (2005) NOD-LRR proteins: role in microbial-host interactions and inflammatory disease. Ann. Rev. Biochem. 74: 355-383.
Lerner Research Institute
Cleveland Clinic,
Mail Code NB21
9500 Euclid Avenue
Cleveland, Ohio 44195
Tel: (216) 444-3900