Jan Jensen, Ph.D. Associate Staff Eddie J. Brandon Endowed Chair in Diabetes Research Director, Diabetes Research Department of Stem Cell Biology and Regenerative Medicine 9500 Euclid Avenue, NE30 Cleveland, Ohio 44195 Telephone: (216) 445-0990 Fax: (216) 636-5454 E-mail: jensenj2@ccf.org

Area of general research interest:

Developmental biology of the pancreas with a focus on the molecular mechanisms controlling insulin-cell development.

Programs:

• Role of FGF10 in pancreatic development
• Evaluation of a novel cell surface marker, Betacam, of pancreatic beta-cells
• Conditional gene activation in developing pancreas
• Adult pancreatic regeneration
• Endodermal progenitor cell maintenance and patterning
• Systems biology of the morphogen-signaling network in the pancreas
• Development of GeneSpeed, GeneSpeed Beta Cell and GeneSpeed Immunolgy: online resources for the islet and immunology research communities.

Investigators:

• Solomon Afelik, Ph.D., Postdoctoral Fellow
• Michael Bukys, Ph.D., Postdoctoral Fellow
• Edy Hasrouni, Research Student
• Yong-Sik Kim, Ph.D, Project Scientist
• Stephan Nieuwoudt, Research Student
• Xiaoling Qu, Ph.D., Postdoctoral Fellow
• Nayeem Quayum, Programmer
• William Rogers, Technician
• Fan Xiao, Technologist

Collaborators:

• Jose Oberholzer, U. Illinois Chicago
• John Hutton, Barbara Davis Center for Childhood Diabetes, U. Colorado HSC
• Steven Leach, Johns Hopkins Medical Institute
• Charles L. Murtaugh, Eccles Institute, U. Utah
• Peter Dempsey, U. Michigan
• James DeGregori, U. Colorado, HSC.
• Anne Grapin-Botton, ISREC, Lausanne, CH.