Faculty Positions

With nearly 1,400 researchers and support personnel in 180 laboratories across 12 departments, the Lerner is one of the largest research institutes in the nation, consistently ranking in the top 10 in National Institutes of Health funding, a benchmark of research success.

Positions for Full, Associate and Assistant Faculty posted by individual research departments.

Date Contact Description
11/14/2018 Kelsey Shirey

The Genomic Medicine Institute (GMI) at the Cleveland Clinic Lerner Research Institute is seeking an assistant/associate/full professor level Faculty (primary research scientists and/or physician-scientists) in the disciplines of germline cancer genetics, cardio-pulmonary/vascular genetics, neurogenetics, renal genomics, population genetics or genomic and systems medicine, who will join a growing team focused on developing research programs in this highly competitive area. The GMI currently includes investigators in the following areas of genomics/epigenomics: cancer and benign blood disorders, neurodegenerative diseases, neurodevelopmental disorders, regulation of CMV and HIV latency, as well as metagenomics encompassing microbiomics/mycobiomics and viromics.

Successful candidates will have the opportunity to interact with the Center for Personalized Genetic Healthcare within the GMI, which includes clinical geneticists and genetic counselors. They will have access to clinical research support specialists, statistical and informatics support, outstanding Core facilities, computational infrastructure for scaled computing, and clinicians and medical subspecialists across the enterprise.

Candidates should have experience in designing and implementing translational, lab-based, and/or animal model research in an academic healthcare or industry setting. Proven proficiency in working with WES, WGS, SNP-array, Methylome, scTranscriptome or Transcriptome data is a must. Current extramural funding is highly desirable but outstanding applicants with strong publication records beginning independent research careers will also be considered. Excellence in collaborative science, academic writing, and communication skills are a must.

Job Requirements

  • M.D. and/or Ph.D. in related disciplines
  • Evidence of academic grant-writing, teaching/mentoring, and a strong publication record befitting career stage
  • Experience in omics technologies desirable but not required

The Cleveland Clinic is an internationally recognized, not-for-profit, multi-specialty academic medical center that integrates clinical and patient care with research and education. It is ranked the #2 hospital in the country by U.S. News & World Report and in 2017, saw over 7 million patients.

The Lerner Research Institute, with nearly 200 independent investigators in 10 departments and an annual budget of >$240 million, has a commitment to excellence in basic, translational and clinical research, with an emphasis on interactive, collaborative research. Faculty are members of the Molecular Medicine Graduate Training Program at Case Western Reserve University School of Medicine, and may join other Programs, providing access to excellent doctoral students enrolled in well-developed training programs.

If interested, please email a copy of your Curriculum Vitae, a letter summarizing your interest and qualifications, and three references to shireyk@ccf.org. Applications will be considered on a rolling basis.

The Cleveland Clinic Foundation is an Equal Opportunity/Affirmative Action employer in a smoke/drug free environment.

10/22/2018 Lauren Forst

Job Title: Biosafety Officer

Job Summary: The biosafety officer serves as an expert resource in the development, implementation, management and improvement of institutional biosafety programs. The biosafety officer oversees the biosafety program, ensures compliance with applicable rules and requirements and uses data to develop corrective and preventative practices and procedures related to biosafety.


  • Develops, implements and directs a comprehensive biosafety program for the health system

  • Ensures organizational compliance with regulatory and sponsor requirements associated with biosafety

  • Serves as a member of Institutional Biosafety Committee (IBC) and assists the IBC Chair by interacting with investigators whose work is under review by committee, reviewing research protocols to ensure adequate biosafety measures are included, providing guidance to IBC on containment issues, implementing IBC-approved policies and plans, and providing administrative support

  • Maintains in-depth knowledge of biosafety principles and best practices and serves as a resource on related federal and state regulations

  • Provides technical guidance to caregivers regarding equipment, facilities and work practices for protection of personnel, laboratories and environment from biological hazards

  • Reviews experimental design, protocols and procedures and conducts risk assessments

  • Reviews research grant applications, proposals, and activities involving biohazardous agents and materials, including, but not limited to recombinant or synthetic nucleic acid (rsNA), infectious agents, toxins, human-derived and nonhuman primate-derived materials, and human gene transfer clinical trials to ensure safe practices in support of the health system’s IBC, Institutional Animal Care and Use Committee (IACUC), and Institutional Review Board (IRB)

  • Ensures facility compliance with regulations and guidelines pertaining to use, handling, shipping, and disposal of potential biohazards and rsNA

  • Develop and administer training programs

  • Investigates accidents in regards to Biosafety issues and develops corrective action plans

  • Assists with investigations and reporting of non-compliance

  • Supervises biosafety professionals

  • Develops and implements emergency response procedures for incidents involving biohazardous agents and materials


  • Master’s Degree or Ph.D. preferred in biological science (i.e., microbiology, bacteriology, virology etc.) or related field, possessing Microbiology training and work experience.

Work Experience

  • Minimum 5 years experience in a biomedical research laboratory or related combination of education and experience

  • Minimum 5 years experience in the field of biological safety in a biomedical research facility

  • Knowledge of NIH Guidelines, NIH/CDC BMBL guidelines, USG Policy for DURC, import and export programs (e.g. CDC IPP, APHIS, Bureau of Industry and Security), OSHA, and granting agency requirements

  • Experience working in or supervising BSL-3 containment research is preferred

  • Experience working with select agents or managing select agents research is preferred


  • Certification or eligible for certification by American Biosafety Association ABSA (RBP or CBSP) is preferred

Please send CV and cover letter to Lauren Forst at forstl@ccf.org

08/21/2018 Shaun Stauffer

Screening & Target Validation Group Leader


The Cleveland Clinic Center for Therapeutics Discovery (C3TD) is seeking candidates for Screening and Target Validation (STV) Group Leader.  The C3TD is a newly forming Center aimed with the mission promote translation of advances in basic science to therapeutics for patients with de-risking efforts focused on the most promising approaches and opportunities.  Investigators at the Lerner Research Institute have long benefited from patient information and clinical access via the major Institutes at CCF and as such have created a significant pipeline of innovative research programs directed at patient care with a true bench-to-bedside vision.  The C3TD is tasked to help investigators bridge their discoveries towards illuminating fundamental biology and advance the most viable approaches with promising clinical benefit and commercial value.  The C3TD will be utilizing state of the art technologies in small molecule library screening, fragment-based screening, x-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns.  A disciplined team culture of chemists and biologists collaborating with primary investigators, physicians, and their lab members will be developed with a keen focus on training and sharing best practices in the drug discovery process.  The identified candidate will have a tremendous opportunity to make an impact in translational science at the Cleveland Clinic across multiple disease areas.  


Education:  PhD in Molecular Pharmacology, Biochemistry or related field


Experience: 8 or more years experience post PhD in a major pharmaceutical company, biotech, or related drug discovery institute with experience in automation, chemical biology, high throughput screening, and assay development using both biochemical and cell-based approaches.


Specific Job Duties:

  • Oversee a team of supporting scientists and technicians. 

  • Guide biochemical and cell-based assay development and apply towards medium and high throughput screening efforts suitable for 96 and 384-well formats

  • Draft and establish robust assay protocols

  • Maintain and manage compound management and repository space within facility

  • Oversee target protein constructs, expression, purification, and characterization to be used in small molecule screening campaigns and structure-based design

  • Interact with chemistry counterparts, lead investigators, and participate in team presentations and articulate new directions and strategies before project teams

  • Serve as project biology co-lead and facilitate direction of project teams and small molecule de-risking efforts

  • Contribute as co-author on research publications as well as co-inventor on patentable subject matter

  • Participate and contribute to government and foundation grant submissions


The level of appointment will be commensurate with experience of the candidate, and opportunities for a faculty appointment within the Cleveland Clinic Lerner College of Medicine will be offered with light teaching and guest lecturing in the broader arena of drug discovery.  The ideal candidate will possess excellent verbal and written communication skills, perform well in a high functioning team environment, and be an active participant in helping the center, investigators, and collaborators obtain translational funding. Experience with target identification/validation techniques highly desired and a proven ability to lead productive research teams in an iterative discovery setting.   In addition, candidate will participate in the facilitation of interactions and projects with outside CROs, collaborators, and sponsored corporate partners.  Interested candidates should direct their curriculum vitae, the names of at least three references, and a letter summarizing their experience and interest to Shaun Stauffer (stauffs2@ccf.org).


Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities are encouraged to apply.
We are a smoke/drug free environment.

09/21/2018 Brian Hobbs

Biostatistics Faculty for Cleveland Clinic Department of Quantitative Health Sciences

The Department of Quantitative Health Sciences (QHS) at the Cleveland Clinic main campus is searching for faculty candidates at the level of assistant or associate staff, to conduct independent research as well as collaborate with Cleveland Clinic investigators in the Taussig Cancer Institute. Successful candidates will join an active group of 96 QHS faculty, biostatisticians, analysts, data scientists, and programmers working in diverse areas of biomedicine.

Candidates should demonstrate both expertise in developing quantitative methodology as well as experience in contributing to multi-disciplinary clinical and/or translational cancer research. Additional requirements include experience designing experimental studies, directing research analysts, and supervising analyses of clinical datasets. Excellent academic writing and communication skills must be clearly demonstrated, with verbal proficiency in the English language required.

Job Requirements

  • PhD in Biostatistics or related discipline

The level of appointment will be commensurate with experience of the candidate, and there are no requirements to obtain salary support. Master’s level statistician personnel support will be provided.   Some teaching of our Cleveland Clinic Lerner College of Medicine medical students as well as oncology residents and fellows is expected. The candidate will be expected to help write collaborative research proposals, grant applications, and manuscripts.  Independent PhD-level methodology research in a related area is expected.

The Cleveland Clinic is a not-for-profit, multi-specialty academic medical center that integrates clinical and hospital care with research and education. The Taussig Cancer Institute has been rated by U.S. News & World Report Magazine among the best cancer institutes in the country and is a part of the NCI designated Case Comprehensive Cancer Center.   The Cancer Institute is a very active research organization with many investigator initiated projects and a robust presence at national meetings

Interested candidates should e-mail their curriculum vitae, the names of at least three references, and a letter summarizing their experience and interest to QHSJobSearchTCI@ccf.org. Further questions regarding the position may be directed to Brian Hobbs (hobbsb@ccf.org; Subject: Taussig faculty position 2018).

Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities are encouraged to apply.
We are a smoke/drug free environment.