Grants


Alcohol Research Grants Awarded to Center Members and Trainees

Current Government-Funded Grants

BROWN, J MARK

PROJECT 1: GUT MICROBIAL METABOKITES AS DRIVERS OF ETHANOL-INDUCED LIVER INJURY

5P50 AA024333-04

CRESCI, GAIL

TARGETING ETHANOL-INDUCED GUT DYSBIOSIS WITH SYNBIOTICS TO TREAT ALCOHOLIC LIVER

5R00 AA023266-05

CRONIGER, COLLEEN

CORE B: ANIMAL MODELS AND CELL ISOLATION CORE

5P50 AA024333-04

DASARATHY, SRINIVASAN

ALCOHOLIC HEPATITIS CLINICAL AND TRANSLATIONAL NETWORK LATE PHASE CLINICAL TRIALS AND OBSERVATIONAL STUDIES 6/9

5U01 AA026976-02

DASARATHY, SRINIVASAN

PROJECT 3: SARCOPENIA OF ALD: REGULATION OF SKELETAL MUSCLE AUTOPHAGY BY ALCOHOL

5P50 AA024333-04

KIM, ADAM

C-TYPE LECTINS AND IMMUNE SURVEILLANCE IN ALD

5K99 AA028048-01

LI, XIAOXIA

IRAKM AND MINCLE IN ALD

5R01 AA023722-05

MCCULLOUGH, ARTHUR

CORE C: CLINICAL CORE

5P50 AA024333-04

MCINTYRE, THOMAS

CORE D: PILOT PROJECT CORE

5P50 AA024333-04

NAGY, LAURA

ROLE OF ADIPOSE IN ETHANOL-INDUCED TISSUE INJURY

5R37 AA011876-21

NAGY, LAURA

19TH AND 20TH INTERNATIONAL SYMPOSIUM ON CELLS OF THE HEPATIC SINUSOID TO BE HELD IN 2017 IN GALWAY, IRELAND AND 2019 IN SYDNEY, AUSTRALIA.

5R13 AA026179-03

NAGY, LAURA

ALCOHOLIC HEPATITIS CONSORTIA: AN INTRAMURAL/EXTRAMURAL COLLABORATION TO UNRAVEL GENETIC DETERMINANTS

5U01 AA026264-03

NAGY, LAURA

MICROBIAL METABOLITES AND INNATE IMMUNITY IN AH: BIOMARKERS OF INJURY AND REPAIR

5U01 AA026938-02

NAGY, LAURA

TRANSCRIPTIONAL AND NON-TRANSCRIPTIONAL FUNCTIONS OF IRF3 IN ALD

1R01 AA027456-01A1

NAGY, LAURA

CORE A: ADMINISTRATIVE CORE

5P50 AA024333-04

NAGY, LAURA

PROJECT 4: INNATE IMMUNITY AND CELL DEATH IN ALD

5P50 AA024333-04

NAGY, LAURA & DE LA MOTTE, CAROL

SPECIFIC-SIZED HYALURONAN: A DUAL TARGETED THERAPY FOR ALD

5R01 AA026764-02

POULSEN, KYLE

HEPATOCYTE-DERIVED MIF: A KEY CONTRIBUTOR TO ALCOHOLIC LIVER DISEASE

5K99 AA026648-02

SUH, HOONKYO

ALCOHOL-INDUCED NEUROGENESIS

5R01 AA022377-05

SUH, HOONKYO

THE ROLE OF HIPPOCAMPAL NEUROGENESIS IN ALCOHOL WITHDRAWAL SEIZURE AND COGNITION

1R01 AA027766-01A1

YOU, MIN

EFFECT OF ETHANOL ON LIPID METABOLISM

5R01 AA013623-16

YOU, MIN

PROJECT 2: LIPIN-1 AND THE DEVELOPMENT OF ALD

5P50 AA024333-04

YOU, MIN

ETHANOL REGULATION OF ADIPONECTIN AND ITS SIGNALING

5R01 AA015951-14

ZHANG, PING

ALCOHOL, HEDGEHOG SIGNAL, AND HSC DYSFUNCTION IN HOST DEFENSE AGAINST SEPTICEMIA

5R01 AA022816-05



PI:

Title:

Project:

Years:

LIN, ZHIYONG

KLF15 AND CIRCADIAN REGULATION OF ALCOHOL-INDUCED LIVER INJURY

R01AA021390

2014-2019

SUH, HOONKYO

ALCOHOL-INDUCED NEUROGENESIS

R01AA022377

2014-2019

MARSHALL, STEPHANIE

THE ROLE OF HEPATIC FMO3 IN ETHANOL INDUCED LIVER INJURY

F32AA023699

2014-2017

DASARATHY, SRINIVASAN

ALCOHOL INDUCES MUSCLE AUTOPHAGY BY A NOVEL AMPK INDEPENDENT PI3K MEDIATED MECHANISM

R21 AA022742

2014-2016

NAGY, LAURA

17TH AND 18TH INTERNATIONAL SYMPOSIUM ON CELLS OF THE HEPATIC SINUSOID

R13AA022579

2013-2015

ROYCHOWDHURY, SANJOY

RIP3-MEDIATED NECROPTOSIS AND ETHANOL-INDUCED LIVER INJURY

5R21AA020941

2013-2015

MCCULLOUGH, ARTHUR

NOVEL THERAPIES FOR ALCOHOLIC HEPATITIS

U01AA021893

2012-2017

NAGY, LAURA

MIF IN PROGRESSION AND TREATMENT OF ALD

U01AA020821

2012-2017

NAGY, LAURA

NOVEL THERAPEUTICS FOR ALCOHOLIC HEPATITIS - CLEVELAND TRANSLATIONAL COMPONENT

U01AA021890

2012-2017

NAGY, LAURA

HEME OXYGENASE-1 AND ALCOHOLIC LIVER DISEASE

R01AA019673

2011-2016

NAGY, LAURA

ALCOHOLIC LIVER DISEASE: BIOCHEMICAL, CELLULAR AND SYSTEMIC RESPONSES TO ETHANOL

P20AA017837

2009-2015

NAGY, LAURA

ETHANOL REGULATION OF KUPFFER CELL SIGNAL TRANSDUCTION

R01AA011975

1999-2015

NAGY, LAURA

ROLE OF ADIPOSE IN ETHANOL-INDUCED TISSUE INJURY

R37AA011876

1998-2019



Center-Funded Pilot and Exploratory Projects: Completed

PI:

Title:

Project:

Years:

LI, XIAOXIA

TLR4-INDUCED MYD88-DEPENDENT AND INDEPENDENT PATHWAYS IN ALCOHOL-INDUCED LIVER DISEASE

EXPLORATORY PROJECT 1

2012-2014

MCINTYRE, TOM

CORRELATING ETHANOL-INDUCED KIDNEY INJURY WITH ALCOHOLIC LIVER DISEASE

EXPLORATORY PROJECT 2

2012-2014

TRAPP, BRUCE

THE ROLES OF COMPLEMENT AND MICROGLIA IN ALCOHOL-RELATED NEUROINFLAMMATION

EXPLORATORY PROJECT 3

2012-2014

ROYCHOWDHURY, SANJOY / LIU, XIULI

RIP3-MEDIATED NECROPTOSIS AND ALCOHOL-INDUCED LIVER INJURY

PILOT PROJECT 1

2011-2013

SAKAGUCHI, TAKUYA

ROLE OF SMALL GTPASES IN ALCOHOL-INDUCED FATTY LIVER DISEASE IN ZEBRAFISH

PILOT PROJECT 2

2011-2013

DASARATHY, SRINIVASAN

ALCOHOL INDUCES SKELETAL MUSCLE AUTOPHAGY BY AN AMPK INDEPENDENT MECHANISM

PILOT PROJECT 3

2012-2013

FELDSTEIN, ARIEL / MCINTYRE, TOM

MITOCHONDRIAL PHOSPHOLIPID OXIDATION IN ALD

EXPLORATORY PROJECT 1

2009-2012

JACOBSEN, DONALD

HOMOCYSTEINE AND ALD

EXPLORATORY PROJECT 2

2009-2012

CRONIGER, COLLEEN / NADEAU, JOSEPH

GENETICS IN THE DEVELOPMENT OF CHRONIC ETHANOL-INDUCED LIVER INJURY

EXPLORATORY PROJECT 3

2009-2012

DASARATHY, SRINIVASAN / MCCULLOUGH, ARTHUR

SKELETAL MUSCLE PROTEIN SYNTHESIS IN CIRRHOTICS

PILOT 1

2009-2011

GHOLEM, PIERRE

SAFETY AND EFFICACY OF CURCURMIN IN THE TREATMENT OF ASH

PILOT 2

2009-2011