Call for Pilot Project Research Proposals

The 2014 Call for Pilot Project Research Proposals is now closed.


Each year, the Mikati Center for Liver Diseases seeks applications for clinical projects and the Cleveland Alcohol Center seeks applications for basic/translational projects related to the pathophysiological effects of alcohol on health to be included as a part of a NIAAA/NIH-funded P50 Alcohol Research Center application. Alcohol research at the Center focuses on four thematic areas of investigation:

1. Measuring biochemical and molecular markers of ethanol-induced stress
2. Assessing cellular responses to ethanol-induced stress
3. Understanding the integrative organismal adaptations to ethanol
4. Translating advances from the laboratory to human clinical experiments


  1. Clinical investigators at all stages of their career development are encouraged to apply.
  2. Basic/translational investigators at all stages of their career development are encouraged to apply.

Award Details

  • Funding range: $25,000 directs costs

  • Funding start date: Dependent on active IRB/IACUC approvals for the project

  • Principal investigator and personnel salary: Allowed

  • Length of support: 1-2 years; funding for the second year is contingent upon evidence of satisfactory progress during year 1, as documented in a progress report

Submission Guidelines


Please submit project proposals using the standard NIH PHS398 forms. Forms and form instructions can be obtained from the NIH site:


Each proposal must include the following components:

1) Cover Page Title of proposal and contact information of PI
2) Detailed Budget Page Detailed justification for first year and second year, if requested
3) Biographical Sketch / Other Support NIH Biosketch
4) Research Plan Maximum 2 pages, including a) Specific Aims b) Significance, c) Innovation, d) Approach


Please email submissions to CAC Director Laura Nagy, PhD at
Investigators may only submit one application per cycle as Principal Investigator.

Selection Criteria and Review Process

Clincal Projects and Basic/Translational Projects will be assessed based on a) relevance to CAC four themes; b) scientific quality; c) likelihood of receiving R01 funding in the future; d) Collaborations/synergies with other CAC investigators. 

Proposals will be reviewed by the Executive Committee of the Mikati Center and CAC.  Based on these reviews and programmatic goals, the Executive Committee will make recommendations for funding.

For questions please contact Laura Nagy at, 216-444-4021 or Alexandra Calabrese at, 216-445-3805.