Area of General Research Interest:
Molecular biology of extracellular proteolysis, extracellular matrix,
arthritis, ADAMTS proteases, developmental biology, cardiovascular biology.
Current Program:
- Molecular networks in extracellular matrix (ECM)
- ADAMTS proteases in mammalian development (gastrulation, neural
crest, limb and vascular biology)
- Proteomics for metalloprotease substrates
- Post-translational modification of proteases and ECM
- Mechanisms of cartilage destruction in arthritis
- Molecular mechanisms of inherited connective tissue disorders
Post-doctoral Fellows:
- David Coe, PhD
- Daniel McCulloch, PhD
Senior Technologist:
Research Technician:
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