Associate Staff

Elizabeth Fisher, Ph.D.

Project Staff

Nikolay A. Kharin, Ph.D.

Joint Appointments

Wiliam J. Davros, Ph.D.
Sandra S. Halliburton, Ph.D.
David Huang, M.D., Ph.D.
James D.Thomas, M.D.
Jean A. Tkach, Ph.D.
Martin S. Weinhous, M.D.

Adjunct Appointments

Peter M. Anderson, Ph.D.
George P. Chatzimavroudis, Ph.D.
Bradley D. Clymer, Ph.D.
Geoffrey Lockwood, Ph.D.
D. Geoffrey Vince, Ph.D.

Biomedical Imaging Facilities Group Info Publications
Whitaker Biomedical Imaging Laboratory

Publications

(proceedings and journal papers - current and past image processing lab members in bold.)


Rudick RA, Cutter G, Baier M, Fisher E, Dougherty D, Weinstock-Guttman B, Mass MK, Miller D, Simonian NA. Predictive value of the multiple sclerosis functional composite in relapsing remitting multiple sclerosis Neurology. 56:1324-1330. 2001.

Diehl B, Najm I, Ruggieri P, Tkach J, Mohamed A, Morris H, Wyllie E, Fisher E, Duda J, Lieber M, Bingaman B, Luders HO. Postictal Diffusion-weighted Imaging for the Localization of Focal Epileptogenic Areas in Temporal Lobe Epilepsy. Epiplesia. 42(1):21-8. 2001.

Fisher E, Rudick RA. Measurement of Atrophy. in Multiple Sclerosis: Mechanisms of Tissue Destruction & Repair and New Immunological Treatments. Kappos, L, Kesselring J, Radü EW. (eds). Martin Dunitz Publishers, London. 2001.

Tsutsui H, Ziada KM, Schoenhagen P, Iyisoy A, Magyar WA, Crowe TD, Klingensmith JD, Vince DG, Rincon G, Hobbs RE, Yamagishi M, Nissen SE, Tuzcu EM. Lumen Loss in Transplant Coronary Artery Disease is a Biphasic Process Involving Early Intimal Thickening and Late Constrictive Remodeling: Results from a 5-Year Serial Intravascular Ultrasound Study. Circulation, In Press, 2001.

Schoenhagen P, Vince DG, Ziada KM, Tsutsui H, Crowe TD, Nissen SE, Tuzcu EM Arterial Expansion (Positive Remodeling) of Bifurcation Lesions is Associated with Unstable Clinical Presentation: An Intravascular Ultrasound Study: American Journal of Cardiology, In press, 2001.

Nair A, Kuban BD, Vince DG. Comparison of the ability of spectral algorithms to predict atherosclerotic plaque composition with radio frequency, normalized and raw intravascular ultrasound data. Ultrasound in Medicine and Biology. In press, 2001.

Sivaramakrishna R, Obuchowski NA, Chilcote WA, Powell KA. Automatic segmentation of mammographic density Academic Radiology 2001 8:12 250-256.

Latson L, Powell KA, Sturm B, Schvartzman PR, White RD. Clinical validation of an automated boundary tracking algorithm on Cardiac MR images. International J of Cardiac Imaging 2001 (in press).

V.Zagrodsky, R.Shekhar, J.F.Cornhill. Multi-function extension of simplex optimization method for mutual information based registration of ultrasound volumes, Proceedings of SPIE, v.4322, p.508-515.

PATENTS

U.S. Patent (US6,200,268): Vascular Plaque Characterization; Vince DG, Kuban BD, Nair A: Issued March 13, 2001.


Fisher E, Rudick RA, Cutter G, Baier M, Miller DM, Weinstock-Guttman B, Mass MK, Dougherty DS, Simonian NA. Relationship Between Whole Brain Atrophy and Disease Course During an 8 Year Follow-Up Study. Multiple Sclerosis. 6(6):373-377.2000.

Rudick RA, Fisher E, Lee J-C, Simon J. Use of the Brain Parenchymal Fraction to Monitor Interferon Beta Therapy In Relapsing Remitting Multiple Sclerosis. Multiple Sclerosis 6(6):365-372. 2000.

Veress A, Vince DG, Anderson PM, Cornhill JF, Herderick EE, Klingensmith JD, Kuban BD, Greenberg NL, Thomas JD. Vascular mechanics of the coronary artery. Z Kardiol. 89 Suppl 2:92-100, 2000.

Cothren RM, Shekhar R, Nissen SE, Tuzcu EM, Cornhill JF, Vince DG . Three-dimensional Reconstruction of the Coronary Artery Wall by Image Fusion of Intravascular Ultrasound and Bi-plane Angiography. International Journal of Cardiac Imaging. 16(2) 69-85, 2000.

Klingensmith JD, Vince DG, Kuban BD, Shekhar R, Tuzcu EM, Nissen SE, Cornhill JF. Assessment of Coronary Compensatory Enlargement by Three-dimensional Intravascular Ultrasound. International Journal of Cardiac Imaging. 16(2) 87-98, 2000.

Vince DG, Dixon KJ, Cothren RM, Cornhill JF. Comparison of Texture Analysis Methods for the Characterization of Coronary Plaques in Intravascular Ultrasound Images. Computerized Medical Imaging and Graphics. 24: (4) 221-229, 2000.

Klingensmith JD, Shekhar R, Vince DG. Evaluation of three-dimensional segmentation algorithms for the identification of luminal and medial-adventitial borders in intravascular ultrasound images. IEEE Transactions on Medical Imaging, 19:(10) 1-17, 2000.

Sivaramakrishna R, Obuchowski NA, Chilcote WA, Cardenosa G, Powell KA. Comparing the performance of mammographic enhancement algorithms: A preference study. AJR 2000 175:45-51.

Powell KA, Mallasch P, Obuchowski NA, Kerczewski R, Ganobcik S, Cardenosa G, Chilcote WA. Clinical evaluation of wavelet compressed digitized film mammograms. Academic Radiology 2000 7(5):311?6.

Obuchowski NA, Lieber ML, Powell KA. Data analysis for detection and localization of multiple radiographic signals with application to mammography. Academic Radiology 2000 7:516-525.

Young A, Dokos S, Powell KA, Sturm B, McCulloch AD, Starling RC, McCarthy P, White RD. Regional heterogeneity of function in nonischemic dilated cardiomyopathy Cardiovascular Research 2000 49(2):308 - 318.

Obuchowski NA, Graham RJ, Baker ME, Powell KA. Ten Criteria for effective screening: Their application to multi-slice CT screening for Pulmonary and colorectal cancers. AJR 2000 176:1357-1362.

V.Zagrodsky, R.Shekhar, J.F.Cornhill. Mutual information based registration of cardiac ultrasound volumes, Proceedings of SPIE, v.3979, p.1605-1614, 2000.


Cothren RM, Shekhar R, Tuzcu EM, Nissen SE, Cornhill JF, and Vince DG. Three-dimensional reconstruction of the coronary artery wall by image fusion of intravascular ultrasound and bi-plane angiography. International Journal of Cardiac Imaging, 1999. In press.

Demirkaya, O, Cothren, RM, Vince, DG, Cornhill, JF. Automated Identification of Stained Cells in Tissue Sections Using Digital Image Analysis. Analytical and Quantitative Cytology and Histology. 21: (2) 93-102 Apr 1999

Gordon R and Sivaramakrishna R. Mammograms are waldograms: why we need 3D longitudinal screening. Invited Guest Editorial, Applied Radiology, 1999. 28: p. 12-25.

Klingensmith JD, Vince DG, Kuban BD, Tuzcu EM, Shekhar R, Nissen SE, and Cornhill JF. Assessment of coronary compensatory enlargement by three-dimensional intravascular ultrasound. International Journal of Cardiac Imaging, 1999. In press.

Klingensmith JD, Vince DG, Shekhar R, Kuban B, Tuzcu EM, and Cornhill JF. Quantification of coronary arterial plaque volume using 3D reconstructions formed by fusing intravascular ultrasound and biplane angiography. Proceedings of SPIE Medical Imaging, 1999. 3660: p. 343-50.

Penn AI, Thompson S, Loew MH, Sivaramakrishna R, and Powell KA. Statistical fractal border features for mammographic breast mass analysis. SPIE Medical Imaging, 1999. 3661: p. 533-40.

Powell KA, Obuchowski NA, Chilcote WA, Barry MM, Ganobcik SN, Cardenosa G. Film-screen versus digitized mammography: Assessment of Clinical Equivalence, AJR 1999 173:889-894.

Powell KA, Obuchowski NA, Davros WJ, Chilcote WA. Quantitative analysis of breast parenchymal density: correlation with women's age. Academic Radiology 1999; 6:742-747.

Rudick RA, Fisher E, Lee J-C, Simon J, Jacobs L, and the Multiple Slcerosis Collaborative Research Group. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Neurology, 1999. 53(8): p. 1698-1704.

Shekhar R, Cothren RM, Vince DG, Chandra S, Thomas JD, and Cornhill JF. Three-dimensional segmentation of luminal and adventitial borders in serial intravascular ultrasound images. Computerized Medical Imaging and Graphics, 1999. 23(6): p. 299-309.

Sivaramakrishna R, Obuchowski N, Chilcote W, Cardenosa G, and Powell K. Comparing the performance of mammographic enhancement algorithms - a preference study. American Journal of Roentgenology, 1999. In press.

Trapp BD, Ransohoff RM, Fisher E, and Rudick RA. Neurodegeneration in multiple sclerosis: Relationship to neurological disability. The Neuroscientist, 1999. 5: p.48-57.


Gaddipati A, Vince DG, Cothren RM, and Cornhill JF. Color microscopy image segmentation using competitive learning and fuzzy-Kohonen networks. Proceedings of SPIE, 1998. 3338(1-2): p. 616-628.

Latson LA, Powell KA, Sturm B, and White RD. Clinical validation of an automated boundary tracking algorithm using cardiac MR images. Computers in Cardiology, 1998. p. 741-744.

Meier DS, Fisher E, Tkach JA, Masaryk T, Cohen JA, and Cornhill JF. Automated anatomical labeling of MRI brain data using spatial atlas warping in a finite element framework. Proceedings of SPIE Medical Imaging, 1998. 3338: p. 1234-1245.

Masseroli M, Cothren RM, Meier DS, Tuzcu EM, Vince DG, Nissen SE, Thomas JD, and Cornhill JF. Quantification of intramural calcification in coronary intravascular ultrasound images with automated image analysis. American Heart Journal, 1998. 136: p. 78-86.

Perktold K, Hofer M, Rappitsch G, Loew M, Kuban BD, and Friedman MH. Validated computation of physiologic flow in a realistic coronary artery branch. Journal of Biomechanics, 1998. 31(3): p. 217-228.


Fisher E, Cothren RM, Tkach JA, Masaryk TJ, and Cornhill JF. Knowledge-based 3D segmentation of MR images for quantitative M.S. lesion tracking. SPIE Medical Imaging, 1997. 3034: p. 599-610.

Fisher E, van der Stelt PF, and Dunn SM. 3D registration of surfaces for change detection in medical images. SPIE Medical Imaging, 1997. 3034: p. 19-35.

Meier DS, Cothren RM, Vince DG, and Cornhill JF. Automated morphometry of coronary arteries with digital image analysis of intravascular ultrasound. American Heart Journal, 1997. 133: p. 681-90.

Sivaramakrishna R and Gordon R. Detection of breast cancer at a smaller size can reduce the likelihood of metastatic spread: a quantitative analysis. Academic Radiology, 1997 4: p. 8-12.

Vince DG, Tbaki A, Gaddipati A, Cothren RM, Cornhill JF, and Tubbs RR. Quantitative comparison of immunohistochemical staining intensity in tissues fixed in formalin and histochoice. Analytical Cellular Pathology, 1997. 15(2): p. 119-129.


Friedman MH, Baker PB, Ding Z, and Kuban BD. Relationship between the geometry and quantitative morphology of the left anterior descending coronary artery. Atherosclerosis, 1996. 125(2): p. 183-192.

Horrigan MCG, MacIsaac AL, Nicolini FA, Vince DG, Lee P, Ellis SG, and Topol EJ. Reduction in myocardial infarct size by basic fibroblastic growth factor following temporary coronary occlusion in the canine model. Circulation, 1996. 94: p. 1927-1933.

Shekhar R, Cothren RM, Vince DG, and Cornhill JF. Fusion of intravascular ultrasound and biplane angiography for three-dimensional reconstruction of coronary arteries. Computers in Cardiology, 1996. p. 5-8.

Shekhar R, Cothren RM, Vince DG, and Cornhill JF. Spatio-temporal localization of intravascular ultrasound data for accurate 3D reconstruction of coronary arteries. Proceedings of IEEE Engineering in Medicine and Biology Society, 1996. 2: p. 668-69.

Shekhar R, Fayyad E, Yagel R, and Cornhill JF. Octree-based decimation of marching cubes surfaces. Proceedings of IEEE Visualization Conference, 1996. p. 335-342.

Sivaramakrishna R. Separation of image parts using 2-D parallel form recursive filters. IEEE Transactions on Image Processing, 1996. 5(1): p. 175-178.

Vince DG, Demirkaya O, Cothren RM, and Cornhill JF. Quantitative analysis of inflammatory cells in aortic atherosclerosis of young adults. Cardiovascular Pathology, 1996. 5(1): p. 3-10.

Zonios GI, Cothren RM, Arendt JT, Wu J, Van Dam J, Crawford JM, Manoharan R, and Feld M.S.. Morphological model of colon tissue fluorescence. IEEE Transactions in Biomedical Engineering, 1996. 43(2): p. 113-22.


Theses and Dissertations

(in order of year)

Zhang P, Texture analysis of tumors in mammographic images. M.S. - Biomedical Engineering Center, The Ohio State University. 1999.

Arendt J, Detection of early cancerous changes and cancer in bladder tissue by autofluorescence and reflectance. Ph.D. - Biomedical Engineering Center, The Ohio State University. 1999.

Klingensmith J, Quantitative analysis of coronary intravascular ultrasound. M.S. - Biomedical Engineering Center, The Ohio State University. 1999.

Dixon K, Characterization of coronary plaque in intravascular ultrasound images using histological correlation. M.S. - Biomedical Engineering Center, The Ohio State University. 1998.

Gaddipati A, Automated color segmentation in quantitative microscopy. Ph.D. - Biomedical Engineering Center, The Ohio State University. 1998.

Demirkaya O, Automated quantitative cellular analysis of immunohistochemically stained tissue sections. Ph.D. - Biomedical Engineering Center, The Ohio State University. 1997.

Shekhar R, Fusion of intravascular ultrasound and biplane angiography for accurate three-dimensional reconstruction of coronary arteries. Ph.D. - Biomedical Engineering Center, The Ohio State University. 1997.

Brandao A, Staging of lymph nodes in esophageal carcinoma using endoscopic ultrasound and image processing. M.S. - Biomedical Engineering Center, The Ohio State University. 1996.

Meier D, Automated morphology of coronary arteries using digital image processing of intravascular ultrasound images. M.S. - Biomedical Engineering Center, The Ohio State University. 1996.

Cesmeli E, Translational and rotational correction of Bjork-Shiley convexo concave 60 degree and 70 degree heart valves. M.S. - Biomedical Engineering Center, The Ohio State University. 1995.

Gaddipati A, Automated classification Of histochemical stained left anterior descending artery images. M.S. - Biomedical Engineering Center, The Ohio State University. 1995.

Hwang C, The quantification of outlet strut offset in radiographic images of the Bjork-Shiley convexo-concave heart valve. M.S. - Biomedical Engineering Center, The Ohio State University. 1995.

Pohlman S, Classification of breast lesions based on quantitative measures of tumor morphology. M.S. - Biomedical Engineering Center, The Ohio State University. 1995.