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Vinod Labhasetwar, Ph.D. Profile Slides Publications Program
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Vinod Labhasetwar, Ph.D.

Staff

Department of Biomedical Engineering (ND20)
Lerner Research Institute
9500 Euclid Avenue
Cleveland, Ohio  44195
Telephone: (216) 445-9364
Fax: (216) 444-9198
labhasv@ccf.org

Area of general research interest

Our focus is on translational NanoMedicine, which involves biomaterial synthesis, formulation design and development, and evaluation of different biocompatible nanoparticle-based platform technologies for targeted drug/gene delivery and imaging agents.  Our current primary research interests are in cancer treatment and detection, delivery of anti-oxidant enzymes in stroke and developing a non-stent approach to inhibition of restenosis.

Current programs

  • Polymer synthesis, nanoparticle formulation, functionalization, characterization
  • Molecular mechanisms of nanoparticle-cell interactions, uptake and intracellular trafficking, and drug efficacy
  • Developing nanoparticles as non-viral gene expression vector
  • Multifunctional magnetic nanoparticles for drug delivery and imaging
  • Cancer treatment, drug resistance, drug combination, drug targeting, 3-D tumor model
  • Stroke, vascular diseases, CNS delivery of anti-HIV drugs
  • Biocompatibility of nanosystems, interactions with model membrane, oxidative stress, clearance

Post Doctoral Fellows

  • Shihua Jin, M.D., Ph.D.
  • Chiranjeevi Peetla, Ph.D.
  • Sivakumar Vijayaraghavalu, Ph.D.

Graduate Students

  • Isaac Adjei
  • Radhika Bhave
  • Susan Westerfield

Undergraduate Student

  • Yuan Lu

Research Technologists

  • Sanja Dimitrijevic, D.V.M.
  • Melissa Jedlicka, M.S. - Lab Manager

Collaborators

  • Diandra Leslie-Pelecky, Ph.D., University of Nebraska, Lincoln, NE.
  • Chris Flask, Ph.D., Case Western Reserve University, OH.
  • Maciej Zborowski, Ph.D., Biomedical Engineering, Cleveland Clinic.
  • Michael A. Vogelbaum, M.D., Ph.D., F.A.C.S., Brain Tumor and Neuro-Oncology Center, Cleveland Clinic.
  • Cynthia J. Meininger, Ph.D., Texas A&M Health Science Center, Temple, TX.
  • Derek Raghavan, M.D., Ph.D., F.A.C.P., F.R.A.C.P., Taussig Cancer Center, Cleveland Clinic.
  • Ernest C. Borden, M.D., Taussig Cancer Center, Cleveland Clinic.