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Vinod Labhasetwar, Ph.D.StaffDepartment of Biomedical Engineering (ND20) |
Area of general research interest
Our focus is on translational NanoMedicine, which involves biomaterial synthesis, formulation design and development, and evaluation of different biocompatible nanoparticle-based platform technologies for targeted drug/gene delivery and imaging agents. Our current primary research interests are in cancer treatment and detection, delivery of anti-oxidant enzymes in stroke and developing a non-stent approach to inhibition of restenosis.
Current programs
- Polymer synthesis, nanoparticle formulation, functionalization, characterization
- Molecular mechanisms of nanoparticle-cell interactions, uptake and intracellular trafficking, and drug efficacy
- Developing nanoparticles as non-viral gene expression vector
- Multifunctional magnetic nanoparticles for drug delivery and imaging
- Cancer treatment, drug resistance, drug combination, drug targeting, 3-D tumor model
- Stroke, vascular diseases, CNS delivery of anti-HIV drugs
- Biocompatibility of nanosystems, interactions with model membrane, oxidative stress, clearance
Post Doctoral Fellows
- Shihua Jin, M.D., Ph.D.
- Chiranjeevi Peetla, Ph.D.
- Sivakumar Vijayaraghavalu, Ph.D.
Graduate Students
- Isaac Adjei
- Radhika Bhave
- Susan Westerfield
Undergraduate Student
- Yuan Lu
Research Technologists
- Sanja Dimitrijevic, D.V.M.
- Melissa Jedlicka, M.S. - Lab Manager
Collaborators
- Diandra Leslie-Pelecky, Ph.D., University of Nebraska, Lincoln, NE.
- Chris Flask, Ph.D., Case Western Reserve University, OH.
- Maciej Zborowski, Ph.D., Biomedical Engineering, Cleveland Clinic.
- Michael A. Vogelbaum, M.D., Ph.D., F.A.C.S., Brain Tumor and Neuro-Oncology Center, Cleveland Clinic.
- Cynthia J. Meininger, Ph.D., Texas A&M Health Science Center, Temple, TX.
- Derek Raghavan, M.D., Ph.D., F.A.C.P., F.R.A.C.P., Taussig Cancer Center, Cleveland Clinic.
- Ernest C. Borden, M.D., Taussig Cancer Center, Cleveland Clinic.