Janet HoughtonDr. Janet A. Houghton, a renowned cancer researcher from St. Jude Children's Hospital in Memphis, Tennessee, has been selected as the new Chair of the Department of Cancer Biology. Dr. Houghton arrived on October 23, 2006 to begin working towards her goals of recruiting new Faculty to the Department, supporting and building upon existing leading research programs, and promoting collaborations with clinical and translational researchers. Read more.

Faculty Directory

janethoughton Janet Houghton, Ph.D.
Chair, Staff
  • The role of death receptors of the TNF receptor superfamily in drug-induced apoptosis
  • Solid tumors, colon carcinoma and rhabdomyosarcoma as specific human diseases
  • Experimental chemotherapy in human tumor xenograft models
Dr. Almasan Alexandru Almasan, Ph.D.
Associate Staff
  • DNA damage responses: radiation-regulated genes in hematologic and epithelial tumors
  • Integration of cellular radiation responses: apoptosis and/or cell cycle control
  • Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
Casey Graham Casey, Ph.D.
Staff
  • Molecular genetics of common human cancers
  • Gene expression and genomic profiling of cancers
  • Genetic epidemiologic studies of human cancers
Colmenares Clemencia Colmenares, Ph.D.
Staff
  • Role of c-ski proto-oncogene in growth and development
Haque Saikh (Jaharul) Haque, Ph.D.
Assistant Staff
  • Cytokine-mediated cell signaling in allergic inflammation and brain cancer
Heston Warren D. Heston, Ph.D.
Staff
  • Prostate cancer development and therapy
  • Targeting of prostate-specific membrane antigen (PSMA) for prostate cancer therapy
Dr. Phil Howe Philip H. Howe, Ph.D.
Staff
  • Molecular mechanism of Transforming Growth Factor Beta growth action
Silverman Robert H. Silverman, Ph.D.
Staff
  • Antiviral mechanisms of RNase L
  • Role of RNase L in the biology of prostate cancer
  • Role of phospholipid scramblase in interferon action
Sizemore Nywana Sizemore, Ph.D.
Assistant Staff
  • Role of aberrant signal transduction by AKT and IkB kinase in controlling gene expression, oncogenesis, and apoptosis in colorectal and other cancers
Yi Taolin Yi, M.D., Ph.D.
Associate Staff
  • The pathogenic role and mechanism of action of protein tyrosine phosphatases in malignant diseases
  • Inhibition of protein tyrosine phosphatases by small chemical molecules in cancer treatment
  • Development of refined inhibitors of protein tyrosine phosphatases as novel therapeutics
Rackley Raymond Rackley, M.D.
Staff (Joint Appointment)
  • Signal transduction pathways impacting pathological conditions of the bladder urothelium and smooth muscle, including bladder cancer
   
 
 
   
 
 
   
 
 
Project Scientists
  • Jaydip Das Gupta, Ph.D. (Silverman Lab)
  • Beihua Dong, M.D. (Silverman Lab)
  • Malathi Krishnamurthy, Ph.D. (Silverman Lab)
  • Suparna Mazumder, Ph.D. (Almasan Lab)
  • Gary Wildey, Ph.D. (Howe Lab)
Research Associates
  • Yang Guo, Ph.D. (Houghton Lab)
  • Ke Yang, Ph.D. (Houghton Lab)
  • Lihong Yin, Ph.D. (Heston Lab)
Joint Appointments
  • Ernest Borden, M.D. (Primary appointment with Taussig Cancer Center)
  • Charles Foster, M.D. (Primary appointment with Pediatric Infectious Diseases)
  • Ram Ganapathi, Ph.D. (Primary appointment with Taussig Cancer Center)
  • Matthew Kalady, M.D. (Primary appointment with Colorectal Surgery)
  • Daniel Lindner, M.D., Ph.D. (Primary appointment with Taussig Cancer Center)
  • Roger Macklis, M.D. (Primary appointment with Taussig Cancer Center)
  • Raymond Rackley, M.D. (Primary appointment with Urology)
  • Michael Vogelbaum, M.D., Ph.D. (Primary appointment with Brain Tumor Institute)
Adjunct Appointments
  • Stanton L. Gerson, M.D. (Case Western Reserve University)
  • Aimin Zhou, Ph.D. (Cleveland State University)