Faculty

	Roy L. Silverstein, M.D.
	Chairman
	Role of CD36 in platelet function CD36 signaling in vascular cells Regulation of angiogenesis by TSR containing proteins
	Josephine C. Adams, Ph.D.
	Staff
	Molecular mechanisms of ECM-cytoskeletal connections and their role in adhesion and migration Function of a novel regulatory protein, muskelin Cell responses to Thrombospondin Oligomers
	Martha K. Cathcart, Ph.D.
	Staff
	Human monocyte activation Respiratory burst activation Lipid oxidation Signal transduction Lipoprotein oxidation
	Guy M. Chisolm, Ph.D.
	Staff, Vice Chairman of the Lerner Research Institute
	Cellular effects of bioactive products of lipoprotein oxidation in inflammation and atherosclerosis Intracellular signaling events of apoptosis in vascular cells induced by bioactive lipids Genetically altered mouse models of vascular disease
	Paul E. DiCorleto, Ph.D.
	Staff, Chairman of the Lerner Research Institute
	Regulation of Endothelial Cell Gene Expression Thrombin and Cytokine Signaling Pathways Homeobox and Y-box Genes in Endothelial Cell Activiation
	Donna M. Driscoll, Ph.D.
	Staff
	Posttranscriptional regulation of gene expression RNA structure and function
	Maria Febbraio, Ph.D.
	Associate Staff
	Scavenger Receptors and Atherosclerosis Fatty Acid Transport and Metabolism Murine Models of Atherosclerosis and Diabetes
	Ariel Feldstein, M.D.
	Staff (Primary appointment with Pediatric Gastroenterology)
	The liver in obesity and type 2 diabetes  Mechanisms of lipotoxicity Mechanisms of inflammation and fibrogenesis during chronic liver injury Lipid homeostasis and liver carcinogenesis
	Paul L. Fox, Ph.D.
	Staff
	Endothelial cell motility Cellular oxidation processes Ceruloplasmin
	Stanley L. Hazen, M.D., Ph.D.
	Staff
	Leukocyte peroxidases Free radicals and reactive oxygen species Oxidative damage of biomolecules in disease
	Donald W. Jacobsen, Ph.D.
	Staff
	Cardiovascular disease Homocysteine metabolism Endothelial cell function Cobalamin and folate biochemistry
	Damir Janigro, Ph.D.
	Staff
	Epilepsy Blood Brain Barrier
	Michael T. Kinter, Ph.D.
	Associate Staff
	Protein sequencing and characterization by tandem mass spectrometry Mechanisms of injury by oxidative stress
	Andrea N. Ladd, Ph.D.
	Assistant Staff
	Pre-mRNA alternative splicing regulation in vertebrate heart and muscle development
	Véronique Lefebvre, Ph.D.
	Assistant Staff
	Transcriptional control of cell fate and differentiation
	Thomas M. McIntyre, Ph.D.
	Staff
	Identify novel inflammatory lipids and characterize the signaling systems they activate Explore intracellular signaling by lysophosphatidic acid Purify the enzyme that synthesizes PAF Purify and clone novel enzymes that degrade PAF
	Richard E. Morton, Ph.D.
	Associate Staff
	Lipid and lipoprotein metabolism Membrane structure-function relationships Lipid-protein interactions
	Ofer Reizes, Ph.D.
	Associate Staff
	Role of syndecans in energy balance and obesity Mechanisms underlying and adipose tissue resistance to weight loss
	Lewis P. Rubin, M.D.
	Staff (Primary appointment with Department of Neonatology)
	pathobiology of carotenoids (carotene, lycopene, lutein stress, glucocorticoids and fetal programming pulmonary mechanotransduction and cellular oxidant stress
	Jonathan D. Smith, Ph.D.
	Staff
	Macrophage cholesterol metabolism Genetics of atherosclerosis susceptibility in mouse models Genetics and drug discovery in mouse models of Alzheimer disease
	Alan J. Zhu, Ph.D.
	Assistant Staff
	Hedgehog signaling Vesicle trafficking Cytoskeletal dynamics

Project Scientists

• Marie-Luise Brennan, Ph.D.
• Bruce Levison, Ph.D.
• Seng Hui Low, Ph.D.
• Gopal Marathe, Ph.D.
• Gary Wildey, Ph.D.
• Renliang Zhang, Ph.D.

Research Associates

• Smarajit Bandyopadhyay, Ph.D.
• John Barbato, Ph.D.
• Ashish Bhattacharjee, Ph.D.
• Unni Chandrasekharan, Ph.D.
• Xiamong Gong, D.V.M., Ph.D
• Michael E. Greenberg, Ph.D.
• Ge Jin, Ph.D.
• Valiyaveettil Manojkumar, Ph.D.
• Ravi Mishra, Ph.D.
• Shaik Rahaman, Ph.D.
• Pavel Shashkin, Ph.D.

Joint Appointments

• Bela Anand-Apte, MBBS, Ph.D. (Primary w/ Cole Eye Institute)
• Jay Ciezki, M.D. (Primary w/ Radiation Oncology)
• John W. Crabb, Ph.D. (Primary w/ Eye Institute)
• Joe G. Hollyfield, Ph.D. (Primary w/ Eye Institute)
• Byron J. Hoogwerf, M.D. (Primary w/ Endocrinology)
• Damir Janigro, Ph.D. (Primary w/ Neurosurgery)
• Mani S. Kavuru, M.D. (Primary w/ Pul, Allergy & Critical Care Med)
• Jonathan Sears, M.D. (Primary w/ Eye Institute)
• Suyu Shu, Ph.D. (Primary w/ Surgery Research)
• Mary Jane Thomassen, Ph.D. (Primary w/ Pulm Critical Care Med)
• Eric J. Topol, M.D. (Primary w/ Cardiovascular Medicine)

Adjunct Appointments

• Stanley Duraj, Ph.D. (Cleveland State University)
• Joe Fontes, Ph.D. (Cleveland State University)
• Sandra Harris-Hooker, Ph.D. (Morehouse School Medicine)
• Diane Kunze, Ph.D. (MetroHealth)
• Lily M. Ng, Ph.D. (Cleveland State University)
• Gerald M. Saidel, Ph.D. (Case Western Reserve University)
• William P. Schilling, Ph.D. (MetroHealth Medical Center)
• Patricia Parsons-Wingerter, Ph.D. (John Glenn Research Center, NASA)
• Crystal Weyman, Ph.D. (Cleveland State University)

Consultants

• Henry Hoff , Ph.D.