Alan J. Zhu, Ph.D. Assistant Staff Department of Cell Biology Lerner Research Institute (NC10) The Cleveland Clinic Foundation 9500 Euclid Avenue Cleveland, Ohio 44195 Tel.: (216) 444-9340 Fax: (216) 444-9404 zhua@ccf.org

Area of general research interest:

• Hedgehog signaling in development and disease

Current program:

• Identifying key regulators controlling Smoothened protein trafficking
• Studying the transporter activity of Patched protein in initiating Hedgehog signaling
• Investigating a Patched-related protein in membrane trafficking in early embryogenesis of Drosophila

Investigators:

• Adam Schoen, B.S., Research Technician
• Ying Su, Ph.D., Postdoctoral Fellow
• Jun-Zheng Zhang, B.S., Graduate Student
• Jason Ospina, Ph.D. Postdoctoral Fellow
• Andrew Michelson, Undergraduate Research Student