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  • Posting #: 671
  • Job Title: Postdoctoral Fellow
  • Contact: Charis Eng, MD, PhD engc@ccf.org
  • Description:

    Drs. Charis Eng (human cancer genomics) and Stephen Grobmyer (Breast Surgical Oncology) are searching for a highly-motivated postdoctoral researcher for the Genomic Medicine Institute at the Cleveland Clinic Lerner Research Institute.  The successful candidate should be interested in inter-disciplinary biomedical science and will apply metagenomic and computational biology skills to interrogating the microbiome to elucidate breast carcinogenesis.

    The Eng Laboratory is a leader in genomic medicine research, providing evidence that will lead to the practice of precision medicine. This opportunity offers an exceptional learning environment to apply principles of basic biology to patient-oriented research. It is anticipated that, through daily interaction with faculty, staff, physician-scientists and collaborators throughout NE Ohio and beyond, the incumbent will gain appreciation for the patient-oriented research process.

    Technical Skill Requirements:
    -Ideal candidates will have a proficiency in broad cancer fields
    - Experience in skills relevant to metagenomics and computational modeling relevant to this field

    -Familiarity with next generation sequencing preferred but not required
    -Ability to independently analyze literature and project data
    -Excellent writing and communication skills in English

    Responsibilities:
    The post-doctoral researcher will work directly on a project requiring interaction with other members of the Eng lab, members of the Genomic Medicine Institute’s clinical team, Dr. Grobmyer and his team in the Cleveland Clinic Breast Center. The successful candidate will conduct experiments and analyze data under Dr. Eng’s mentorship. As part of these studies, the postdoctoral researcher will be directly responsible for designing experiments and analyzing the data, under her mentorship. Additionally, the successful candidate will be expected to develop a proficiency in the topic through a continuous survey and review of the existing literature.

    Other Attributes:
    -Must be capable of working independently.
    -Ability to work proactively required.
    -Must have strong organizational skills and an ability to follow regulatory best lab practices with regard to data handling.

    -Must have good interpersonal skills
    -Must have a high degree of self-motivation fueled by a fundamental interest in contributing to science in particular.

    Qualifications
    A completed Ph.D. in the area of bioinformatics, computational biology, systems biology or genomics. Strong publication record demonstrating the ability to model, analyze and understand complex data.

     Please send your curriculum vitae and contact information for 3 references to Charis Eng, MD, PhD at engc@ccf.org

     

  • Posting #: 686
  • Job Title: Postdoctoral Fellow
  • Contact: Bin Zhang, Ph.D. zhangb@ccf.org
  • Description:

    A Postdoctoral Fellow position is available in the laboratory of Dr. Bin Zhang in the Genomic Medicine Institute, Cleveland Clinic Lerner Research Institute. Our lab is interested in protein trafficking defects as pathogenic mechanisms of human diseases. We are using a variety of approaches including cell biology, biochemistry and mouse models to understand the functions of a number of proteins important in the secretory pathway. Candidates with a strong background in molecular and cellular biology or biochemistry are encouraged to apply.

    Candidates should have a recent (or be close to finishing) Ph.D. and must demonstrate proficiency in English speaking and writing skills. The Cleveland Clinic Lerner Research Institute provides an excellent interactive environment with access to state-of-the-art equipment and facilities. To apply, please send a cover letter detailing your research experience and interests, curriculum vitae and the contact information for three references to Bin Zhang via email to zhangb@ccf.org.

  • Posting #: 702
  • Job Title: Postdoctoral Fellow
  • Contact: Charis Eng, M.D., Ph.D. engc@ccf.org
  • Description:

    We are seeking a highly motivated Postdoctoral Fellow to join the Charis Eng lab at the Cleveland Clinic Genomic Medicine Institute.  We focus on studying the role of tumor suppressor PTEN in cancer predisposition compared to its role in autism.  As such, we plan to utilize stem cell and mouse modeling approached to dissect out the “switch” between PTEN-related cancer predisposition and PTEN-related autism development.  Since Dr. Eng is a physician-scientist, we aim to translate our research to practice precision medicine.  Applicants must have a PhD in stem cell biology, neurosciences or related field.   Prior experience with stem cell biology and mouse modeling is preferred.  Applicants must have proficiency in spoken and written English.

    For more information about our laboratory, please visit our website: http://lerner.ccf.org/gmi/eng/

    Interested applicants should send their CV, research interests and contact information for 3 references to engc@ccf.org

  • Posting #: 720
  • Job Title: Postdoctoral fellow
  • Contact: Angela Ting tinga@ccf.org
  • Description:

    A Postdoctoral Fellow position is available in the laboratory of Dr. Angela Ting at the Cleveland Clinic Lerner Research Institute. Our research focuses on understanding the functional impact of abnormal DNA methylation on cancer aggressiveness. We employ next generation sequencing (NGS) technologies to identify epigenetic changes throughout the genome and carry out mechanistic studies to define the functions of these changes and their impact on prostate cancer biology. We are particularly interested in developing and testing hypotheses for novel alterations outside of the gene promoter context.

    A successful candidate is expected to be highly motivated with expertise in one or more of the following: RNA biology, protein-protein interactions, transcription mechanisms, genomics, and/or computational biology.

    Please send your curriculum vitae and contact information for 3 references to Angela Ting (tinga@ccf.org).

Applications for technical research positions and administrative positions at the Lerner Research Institute can be submitted on the Cleveland Clinic jobs web site.