Message from the Chair
Greetings from Cleveland Clinic's Genomic Medicine Institute (GMI)!
As I write this, Cleveland Clinic Innovations is hosting the 15th Medical Innovation Summit, for which GMI helped select precision medicine and genomics programming. Rather serendipitously, the theme that emerges throughout this quarter’s newsletter is that of innovation in genomic medicine (ie, genomics in precision medicine). At Cleveland Clinic’s Genomic Medicine Institute and its clinical arm, the Center for Personalized Genetic Healthcare (CPGH), we bridge innovative genomics research and precision patient care. Our goal is to turn research discoveries into clinical practices and management for individuals impacted by genetic-based diseases.
When you or someone you love is coping with illness, it can sometimes feel as though scientific advances move quite slowly. There are many factors at play that can impede the translation of discoveries from the bench to the bedside, including ethical questions, costs, and regulatory hurdles. CRISPR technology has received a lot of attention lately, which is not surprising. When a disruptive new technology emerges in clinical care, skepticism and controversy often greet it.
This is indeed a very exciting time in genomic medicine, and these innovations are making their way to patient care. When Dr. Ting sat down to write her article about genetic testing for men with prostate cancer, the National Comprehensive Cancer Network (NCCN) had not issued formal guidelines stating who might benefit from genetic testing. Only days later, Dr. Ting updated the article because the NCCN released guidelines indicating that genetic testing should be ordered for all men with metastatic prostate cancer.
We are very pleased to welcome our new primary investigator, Dan Blankenberg, PhD, who specializes in developing algorithms and tools to analyze ever-growing amounts of biomedically-relevant big data. Dr. Blankenberg joins us from Pennsylvania State University, where he co-developed Galaxy, a web-based “one-stop-shop” for genome analysis.
Thank you for your interest in learning more about genomic medicine. For additional information about the Genomic Medicine Institute at the Cleveland Clinic, visit us at my.clevelandclinic.org/genomics-genetics.
Charis Eng, MD, PhD, FACP
American Cancer Society Clinical Research Professor
Sondra J. and Stephen R. Hardis Chair of Cancer Genomic Medicine
Chair, Genomic Medicine Institute
Director, Center for Personalized Genetic Healthcare