Cleveland Clinic Study Finds No Association Between Influenza Vaccine and COVID-19 Risk
09/21/2020

Using patient data from Cleveland Clinic’s COVID-19 registry, Dr. Zein found that receiving the flu vaccine does not increase risk for COVID-19 or worsen associated disease outcomes, suggesting it is safe and advisable to receive the influenza vaccine this flu season.

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$2.6M Grant Awarded by NIH to Identify Possible Targets for Treating Alcohol-Related Organ Damage
09/18/2020

Dr. Cresci will explore how increasing levels of two molecules commonly depleted as a result of chronic alcohol exposure may help to rescue pathologies of alcohol use disorder, including bacterial imbalances, leaky gut and increased circulating toxins.

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Department of Defense Funds Research for Potential New Drug to Treat Obesity and Pre-Diabetes
09/14/2020

Investigating inter-organ cross-talk between the gut and immune system, Drs. de la Motte and Nagy will test HA35 as potential therapeutic for Western diet-induced metabolic syndrome.

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Study Finds Air Pollution Can Impact the Pathology of Respiratory Syncytial Virus Common in Children
09/01/2020

Dr. Rezaee showed that nanoparticles of titanium dioxide, a pollutant found in many household and personal care products, exacerbates RSV-associated airway inflammation and other disease-related changes.

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New NIH Grant Awarded to Interrogate a Novel Bronchodilator Candidate to Treat Asthma
08/31/2020

Dr. Ghosh will use the support to investigate for the first time how targeting the nitric oxide receptor may offer alternative bronchodilatory benefits that can help treat severe asthma.

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NIH Awards Grant to Study Creeping Fat and Develop Crohn’s Disease Treatments
08/28/2020

Dr. Rieder seeks to identify new mechanisms responsible for fibrosis and stricture formation that leads to the development of novel preventive and therapeutic treatments for Crohn’s disease.

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Potential New Drug Target for Steroid-Resistant Inflammatory Diseases Uncovered
07/27/2020

Dr. Min and colleagues uncovered a key contribution of regulatory T cells during glucocorticoid-mediated treatment of inflammation, elucidating a possible new, related target for treating aggressive inflammatory diseases.

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A Possible Genetic Cause for Racial Disparities in Preeclampsia
07/21/2020

Dr. Bruggeman shows in a new study that genetic variants to the APOL1 gene are associated with increased risk for pregnancy-induced hypertension in African American women.

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Chronic E-Cigarette Use Linked with Long-Term Lung Injury in Teens, Reports New Study
06/23/2020

New research led by Dr. Rezaee builds upon a growing body of evidence that points to vaping products containing THC as most harmful for teens and adolescents.

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Characterizing Copper’s Role in Colon Cancer Progression
03/02/2020

Researchers led by Dr. Li identified a novel signaling cascade that links inflammation and colorectal cancer, where elevated levels of the pro-inflammatory protein interleukin 17 leads to an accumulation of intracellular copper and ultimately disrupts anti-tumoral defenses.

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Loss-of-Function APOL1 Variants and Environmental Stress Together May Drive Chronic Kidney Disease
01/30/2020

By studying a model of HIV-associated nephropathy, a group of kidney disease researchers and clinicians discovered that in patients with the APOL1 risk gene, the presence of an environmental stressor, like a virus, can trigger cell changes that lead to chronic kidney diseases.

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A New Approach to Treating Infectious Disease
12/30/2019

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Florian Rieder Honored for IBD Research and Care With Sherman Prize
12/16/2019

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New Chair Named for Department of Inflammation & Immunity
12/16/2019

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Mechanical Signaling Cascade Central to Fibrotic Scar Tissue Development Defined
11/13/2019

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Uncovering How Hemeprotein Maturation, Regulation Contributes to Disease
09/09/2019

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Beyond the Gut: The Urinary Tract Microbiome’s Role in Urinary Stone Disease
08/26/2019

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Helmsley Trust Awards $4.3M for Crohn’s Disease Research
04/15/2019

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Defining the Link Between Inflammation and Cancer
01/29/2019

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Five Researchers Win Annual Fund Grants
01/09/2019

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The Search for Causes of Idiopathic Pulmonary Arterial Hypertension
01/03/2019

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New Lerner Core to Provide Human Biological Samples for Discovery
09/05/2018

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New LRI Co-Laboratories Announced
07/03/2018

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How Non-Immune Cells Trigger Inflammation in Asthma
07/03/2018

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