About Us

Paul DiCorleto, PhD Welcome to Cleveland Clinic's Lerner Research Institute. Cleveland Clinic has a long-standing reputation for excellence in patient care, education and clinical and basic research. U.S. News & World Report has consistently ranked Cleveland Clinic among the best hospitals in the nation. In 2013, Cleveland Clinic was ranked the fourth best hospital in the United States and #1 in Ohio.

The Lerner Research Institute is home to Cleveland Clinic's laboratory-based, translational and clinical research. Nearly 2,000 scientists and support personnel pursue a wide range of biomedical questions with the common goal of improving human health.

Some important points:

  • Our research programs focus on disease-oriented areas of study, including: cardiovascular, cancer, neurologic, musculoskeletal, allergic and immunologic, eye, metabolic, and infectious diseases.
  • We have a dedicated 700,000 square feet of state-of-the-art laboratory and clinical research space.
  • Our Genomic Medicine Institute opened in 2005. The facility places Lerner Research Institute at the forefront of this exciting area of exploration and discovery.
  • We are committed to academic excellence, and the great majority of our faculty also have appointments at the nearby Case Western Reserve University, Cleveland State University, Kent State University and/or University of Akron.
  • We are an integral part of the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University—a program dedicated to training the next generation of physician-scientists.
  • The institute is home to nearly 180 graduate students engaged in research that can lead to new understanding of disease, clinical tools and therapies. In addition to collaborative programs with local universities, our unique Molecular Medicine PhD program integrates medicine with traditional graduate training in biomedical research.
  • Total annual research expenditures exceed $250 million, including more than $100 million in federal funding.
  • Our faculty publish approximately 1,300 research articles per year, many of which appear in high-impact journals.
  • Our investigators are very active in commercialization, generating many licenses, patents and spin-off companies each year.
  • Lerner Research Institute researchers are supported by an outstanding array of subsidized, state-of-the-art core facilities.

In addition to the abundance of basic research occurring in the Lerner Research Institute, many physicians throughout Cleveland Clinic conduct translational and clinical research here and hold joint appointments in our departments. The high level of enthusiasm for applying the latest basic scientific knowledge to ongoing clinical questions leads to many fruitful collaborations and a rapid transition from benchtop to bedside.

I welcome you to the Lerner Research Institute.

Paul E. DiCorleto, PhD
Sherwin-Page Chair
Lerner Research Institute