Faculty Positions

Positions for Full, Associate and Assistant Faculty posted by individual research departments.

Date Contact Description
08/21/2018 Shaun Stauffer
stauffs2@ccf.org

Screening & Target Validation Group Leader

 

The Cleveland Clinic Center for Therapeutics Discovery (C3TD) is seeking candidates for Screening and Target Validation (STV) Group Leader.  The C3TD is a newly forming Center aimed with the mission promote translation of advances in basic science to therapeutics for patients with de-risking efforts focused on the most promising approaches and opportunities.  Investigators at the Lerner Research Institute have long benefited from patient information and clinical access via the major Institutes at CCF and as such have created a significant pipeline of innovative research programs directed at patient care with a true bench-to-bedside vision.  The C3TD is tasked to help investigators bridge their discoveries towards illuminating fundamental biology and advance the most viable approaches with promising clinical benefit and commercial value.  The C3TD will be utilizing state of the art technologies in small molecule library screening, fragment-based screening, x-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns.  A disciplined team culture of chemists and biologists collaborating with primary investigators, physicians, and their lab members will be developed with a keen focus on training and sharing best practices in the drug discovery process.  The identified candidate will have a tremendous opportunity to make an impact in translational science at the Cleveland Clinic across multiple disease areas.  

 

Education:  PhD in Molecular Pharmacology, Biochemistry or related field

 

Experience: 8 or more years experience post PhD in a major pharmaceutical company, biotech, or related drug discovery institute with experience in automation, chemical biology, high throughput screening, and assay development using both biochemical and cell-based approaches.

 

Specific Job Duties:

  • Oversee a team of supporting scientists and technicians. 

  • Guide biochemical and cell-based assay development and apply towards medium and high throughput screening efforts suitable for 96 and 384-well formats

  • Draft and establish robust assay protocols

  • Maintain and manage compound management and repository space within facility

  • Oversee target protein constructs, expression, purification, and characterization to be used in small molecule screening campaigns and structure-based design

  • Interact with chemistry counterparts, lead investigators, and participate in team presentations and articulate new directions and strategies before project teams

  • Serve as project biology co-lead and facilitate direction of project teams and small molecule de-risking efforts

  • Contribute as co-author on research publications as well as co-inventor on patentable subject matter

  • Participate and contribute to government and foundation grant submissions

 

The level of appointment will be commensurate with experience of the candidate, and opportunities for a faculty appointment within the Cleveland Clinic Lerner College of Medicine will be offered with light teaching and guest lecturing in the broader arena of drug discovery.  The ideal candidate will possess excellent verbal and written communication skills, perform well in a high functioning team environment, and be an active participant in helping the center, investigators, and collaborators obtain translational funding. Experience with target identification/validation techniques highly desired and a proven ability to lead productive research teams in an iterative discovery setting.   In addition, candidate will participate in the facilitation of interactions and projects with outside CROs, collaborators, and sponsored corporate partners.  Interested candidates should direct their curriculum vitae, the names of at least three references, and a letter summarizing their experience and interest to Shaun Stauffer (stauffs2@ccf.org).

 

Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities are encouraged to apply.
We are a smoke/drug free environment.

09/21/2018 Brian Hobbs
qhsjobsearchtci@ccf.org

Biostatistics Faculty for Cleveland Clinic Department of Quantitative Health Sciences

The Department of Quantitative Health Sciences (QHS) at the Cleveland Clinic main campus is searching for faculty candidates at the level of assistant or associate staff, to conduct independent research as well as collaborate with Cleveland Clinic investigators in the Taussig Cancer Institute. Successful candidates will join an active group of 96 QHS faculty, biostatisticians, analysts, data scientists, and programmers working in diverse areas of biomedicine.

Candidates should demonstrate both expertise in developing quantitative methodology as well as experience in contributing to multi-disciplinary clinical and/or translational cancer research. Additional requirements include experience designing experimental studies, directing research analysts, and supervising analyses of clinical datasets. Excellent academic writing and communication skills must be clearly demonstrated, with verbal proficiency in the English language required.

Job Requirements

  • PhD in Biostatistics or related discipline

The level of appointment will be commensurate with experience of the candidate, and there are no requirements to obtain salary support. Master’s level statistician personnel support will be provided.   Some teaching of our Cleveland Clinic Lerner College of Medicine medical students as well as oncology residents and fellows is expected. The candidate will be expected to help write collaborative research proposals, grant applications, and manuscripts.  Independent PhD-level methodology research in a related area is expected.

The Cleveland Clinic is a not-for-profit, multi-specialty academic medical center that integrates clinical and hospital care with research and education. The Taussig Cancer Institute has been rated by U.S. News & World Report Magazine among the best cancer institutes in the country and is a part of the NCI designated Case Comprehensive Cancer Center.   The Cancer Institute is a very active research organization with many investigator initiated projects and a robust presence at national meetings

Interested candidates should e-mail their curriculum vitae, the names of at least three references, and a letter summarizing their experience and interest to QHSJobSearchTCI@ccf.org. Further questions regarding the position may be directed to Brian Hobbs (hobbsb@ccf.org; Subject: Taussig faculty position 2018).

Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities are encouraged to apply.
We are a smoke/drug free environment.