Ganes C. Sen, Ph.D. Chairman, Department of Molecular Genetics Thomas Lord Endowed Chair in Molecular Biology Lerner Research Institute / NE20 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 444-0636 Fax: (216) 444-0513 E-mail: seng@ccf.org

Areas of general research interest:

Host response to virus infection and tissue-specific functions of angiotensin-converting enzymes

Current programs:

• Double-stranded RNA & TLR3-mediated signaling
• Functions & structures of P56 & OAS: two multimember families of viral stress-inducible proteins
• Cellular & developmental roles of PACT, a dsRNA-binding protein
• Tissue-specific functions of ACE

Investigators:

• Chang, Yunhai
• Chattopadhyay, Saurabh, Ph.D.
• Desai, Avanti, M.S.
• Dickerman, Benjamin, M.S.
• Elco, Christopher
• Fensterl, Volker, Ph.D.
• Lu, Lenette
• Majumder, Pritha, Ph.D.
• Peters, Gregory, Ph.D.
• Saikia, Paramananda, Ph.D.
• Sarkar, Saumendra, Ph.D.
• Smith, Kevin, B.S.
• White, Christine, Ph.D.
• Yamashita, Michifumi, M.D.

Collaborators:

• Jun Qin, Ph.D., Department of Molecular Cardiology
• George Stark, Ph.D., Department of Molecular Genetics
• Bryan Williams, Ph.D., Monash Institute of Medical Research, Australia