Tatiana Byzova, Ph.D. Staff Joint Appointment with Cardiology and Taussig Cancer Center Department of Molecular Cardiology Center for Thrombosis and Vascular Biology Lerner Research Institute / NB50 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 445-4312 (office); (216) 445-8237 (lab) Fax : (216) 444-9263 byzovat@ccf.org

Area of General Research Interest:

Cell adhesion molecules (integrins) in thrombosis, vascular biology and cancer, vascular endothelial growth factors, angiogenesis, extracellular matrix including bone matrix proteins.

Current Research:

• Mechanisms of α_Vβ₃ integrin activation on blood and endothelial cells in hemostasis and angiogenesis
  
  
• Role of tyrosine phosphorylation of a_Vb₃ in the process of activation
  
  
• Role of integrin activation in the recognition of bone matrix as related to the prostate cancer bone metastasis

Investigators:

• Choi, Jeong-suk, Ph.D., Postdoctoral Fellow
• Ciocea, Alieta, Ph.D., Postdoctoral Fellow
• Kerr, Bethany, Ph.D., Postdoctoral Fellow
• Ma, Lining, M.D., Ph.D., Research Associate
• Madajka, Maria, Ph.D., Postdoctoral Fellow
• Malinin, Nikolai, Ph.D., Postdoctoral Fellow
• Merkulova, Alona, Lead Technologist
• Pavkov, Mircea, Ph.D., Postdoctoral Fellow
• Pustovalova, Olga L., Predoctoral Fellow
• Shenoy, Somanath Rammohan, Ph.D., Project Scientist
• Tischenko, Miroslava, Technician
• Zhang, Xiaoxia, Graduate Student

Collaborators:

• Warren Heston, Ph.D., Cancer Biology, CCF
• Ronald Midura, Ph.D., Biomedical Engineering, CCF
• Edward F. Plow, Ph.D., Molecular Cardiology, CCF
• Maria Siemionow, M.D., Ph.D., Plastic and Reconstructive Surgery, CCF
• Eric J. Topol, M.D., Scripps Institute

Former trainees:

• Wesley Kim, B.S., 1998-2000.
• Emil Negresku, M.D., Ph.D., 1999-2000.
• Shannon Durkin, B.S., 2000-2001.
• Vicky Byers-Ward, B.S., 1999-2003.
• Thomas Brahler, student from Wesleyan University, OH, 2003.
• Anastacia Canacci, M.D., 2003-2004.
• Alena Nikolskaya, Ph.D., 2003-2004.