Publications

Mahabeleshwar GH, et al. Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis. Circ Res 2007;101:570-80.
Somanath PR, et al. Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly. J Biol Chem 2007;282:22964-76.
McCabe NP, et al. Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling. Oncogene 2007;26:6238-43.
Mahabeleshwar GH, et al. Integrin signaling is critical for pathological angiogenesis. J Exp Med 2006;203:2495-507.
Juhua Chen, Payaningal R Somanath, Olga Razorenova, William S Chen, Nissim Hay, Paul Bornstein & Tatiana V Byzova. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nature Medicine 11, 1188-1196, 2005. [Web]
Sarmishtha De, Olga Razorenova, Noel Patrick McCabe, Timothy O'Toole, Jun Qin, and Tatiana V. Byzova. VEGF-integrin interplay controls tumor growth and vascularization. PNAS, May 24, 2005, vol. 102, no. 21, 7589-7594. [Web]
De S, Chen J, Narizhneva NV, Heston W, Brainard J, Sage EH, Byzova TV. Molecular pathway for cancer metastasis to bone. J Biol Chem. 2003 Oct 3;278(40):39044-50. Epub 2003 Jul 28. PMID: 12885781
Quinn MJ, Byzova TV, Qin J, Topol EJ, Plow EF. Integrin {alpha}IIb{beta}3 and Its Antagonism. Arterioscler Thromb Vasc Biol. 2003 Jun;23(6):945-952. Epub 2003 Mar 13. PMID: 12637342
Byzova TV, Goldman CK, Jankau J, Chen J, Cabrera G, Achen MG, Stacker SA, Carnevale KA, Siemionow M, Deitcher SR, DiCorleto PE. Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo. Blood. 2002 Jun 15;99(12):4434-42. PMID: 12036873
Byzova TV, Goldman CK, Pampori N, Thomas KA, Bett A, Shattil SJ, Plow EF. A mechanism for modulation of cellular responses to VEGF: activation of the integrins. Mol Cell. 2000 Oct;6(4):851-60. PMID: 11090623
Byzova TV, Plow EF. The Pl(A2) allele and cardiovascular disease: the pro(33) and con. J Clin Invest. 2000 Mar;105(6):697-8. No abstract available. PMID: 10727434
Byzova TV, Kim W, Midura RJ, Plow EF. Activation of integrin alpha(V)beta(3) regulates cell adhesion and migration to bone sialoprotein. Exp Cell Res. 2000 Feb 1;254(2):299-308. PMID: 10640428
Cierniewski CS, Byzova T, Papierak M, Haas TA, Niewiarowska J, Zhang L, Cieslak M, Plow EF. Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses. J Biol Chem. 1999 Jun 11;274(24):16923-32. PMID: 10358039
Topol EJ, Byzova TV, Plow EF. Platelet GPIIb-IIIa blockers. Lancet. 1999 Jan 16;353(9148):227-31. Review. PMID: 9923894
Byzova TV, Plow EF. Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin. J Cell Biol. 1998 Dec 28;143(7):2081-92. PMID: 9864377
Byzova TV, Plow EF. Networking in the hemostatic system. Integrin alphaiibbeta3 binds prothrombin and influences its activation. J Biol Chem. 1997 Oct 24;272(43):27183-8. PMID: 9341161
Mazurov AV, Khaspekova SG, Byzova TV, Tikhomirov OYu, Berndt MC, Steiner B, Kouns WC. Stimulation of platelet glycoprotein IIb-IIIa (alpha IIb beta 3-integrin) functional activity by a monoclonal antibody to the N-terminal region of glycoprotein IIIa. FEBS Lett. 1996 Aug 5;391(1-2):84-8. PMID: 8706936
Plow EF, Byzova T. The biology of glycoprotein IIb-IIIa. Coron Artery Dis. 1999 Dec;10(8):547-51. Review. No abstract available. PMID: 10599532
Plow EF, Cierniewski CS, Xiao Z, Haas TA, Byzova TV. AlphaIIbbeta3 and its antagonism at the new millennium. Thromb Haemost. 2001 Jul;86(1):34-40. Review. PMID: 11487023
Byzova TV, Rabbani R, D'Souza SE, Plow EF. Role of integrin alpha(v)beta3 in vascular biology. Thromb Haemost. 1998 Nov;80(5):726-34. Review. No abstract available. PMID: 9843163
Mazurov AV, Pevzner DV, Antonova OA, Byzova TV, Khaspekova SG, Semenov AV, Vlasik TN, Samko AN, Staroverov II, Ruda MY. Safety, inhibition of platelet aggregation and pharmacokinetics of Fab'2 fragments of the anti-glycoprotein IIb-IIIa monoclonal antibody FRaMon in high-risk coronary angioplasty. Platelets. 2002 Dec;13(8):465-77. PMID: 12487780
Mazurov AV, Pevzner DV, Khaspekova SG, Dudnik OA, Byzova TV, Vlasik TN, Bakharev VN, Pistsov MIu, Staroverov II, Ruda MIa. [Inhibition of thrombocyte aggregation by F(ab')2-fragments of monoclonal antibodies FraMon (CRC64) to glycoproteins IIb-IIIa] Ter Arkh. 2001;73(9):66-73. Russian. PMID: 11642086
Byzova TV, Romanov IuA, Blasik TN, Mazurov AV. [Interaction of a monoclonal antibody to P-selectin with activated platelets and endothelial cells. Heterogeneity of expressing P-selectin in human aorta endothelial cells] Biokhimiia. 1995 Aug;60(8):1292-301. Russian. PMID: 7578581
Bochkov VN, Sorokin EV, Byzova TV, Mazurov AV, Little P, Bobik A, Tkachuk VA. [Do glycoproteins IIb/IIIa participate in activation of human platelet s by low density lipoproteins?] Biokhimiia. 1995 Aug;60(8):1187-94. Russian. PMID: 7578573
Romanov YA, Balyasnikova IV, Bystrevskaya VB, Byzova TV, Ilyinskaya OP, Krushinsky AV, Latsis RV, Soboleva EL, Tararak EM, Smirnov VN. Endothelial heterogeneity and intimal blood-borne cells. Relation to human atherosclerosis. Ann N Y Acad Sci. 1995 Jan 17;748:12-37; discussion 37-9. No abstract available. PMID: 7535024
Byzova TV, Vlasik TN, Mazurov AV. [Inhibition of platelet aggregation with monoclonal antibodies to the glycoprotein IIb-IIIa complex] Biull Eksp Biol Med. 1994 Oct;118(10):402-5. Russian. No abstract available. PMID: 7865820
Khaspekova SG, Vlasik TN, Byzova TV, Vinogradov DV, Berndt MC, Mazurov AV. Detection of an epitope specific for the dissociated form of glycoprotein IIIa of platelet membrane glycoprotein IIb-IIIa complex and its expression on the surface of adherent platelets. Br J Haematol. 1993 Oct;85(2):332-40. PMID: 7506568