Qing Kenneth Wang, Ph.D., M.B.A.

Staff and Professor

Lerner Research Institute
9500 Euclid Avenue
Cleveland, Ohio 44195
Phone: (216) 445-0570
Fax: (216) 636-1231

Dr. Wang has made distinguished contributions to the field of genetics of cardiovascular and neurological diseases by identifying eight genes for single gene disorders and three candidate genes for common complex disease, and by identifying novel molecular mechanismsunderlying channelopathies and other diseases. He was noted for reporting the discoveries of the first Brugada syndrome gene (SCN5A), the most common gene for long QT syndrome (LQTS) (KCNQ1), one of the first two genes reported for LQTS in the same issue of Cell (SCN5A), LQTS gene KCNE1, the first gene for autosomal recessive atrial fibrillation (NUP155), atrial fibrillation gene SCN3B, the first gene for vascular disease Klippel-Trenaunay syndrome (AGGF1), and the first gene for co-existent paroxysmal dyskinesia and generalized epilepsy (KCNMA1). Dr. Wang also identified candidate genes for familial, early-onset coronary artery disease (CAD), completed the first genome-wide association study for CAD in a non-Caucasian population and identified C6orf105 as a new CAD susceptibility gene. Dr. Wang’s early discoveries on cardiac arrhythmias genes have been translated into the first commercial genetic testing kit in the field of cardiovascular medicine (Familion Test), which realized the first successful case of personalized genomic medicine in cardiovascular medicine and saved many human lives. Dr. Wang has identified a protein MOG1 that interacts with the cardiac sodium channel and regulates trafficking of this channel to cell membranes, and established AGGF1 as a VEGF-A-like angiogenic factor for specifying veins (in contrast to arterial specification by VEGF-A).

In other words ...

Qing Wang is currently Staff at Department of Molecular Cardiology, Department of Cardiovascular Medicine, and Neurological Institute, and the Director of Center for Cardiovascular Genetics at the Cleveland Clinic. He is Professor of Molecular Medicine and Professor of Genetics at Case Western Reserve University.  He received B.S. from China in 1984, Ph.D. in Genetics and Developmental Biology from Cornell University in 1993, and M.B.A. from Cleveland State University in 2002.  His postdoctoral research training was with Dr. Mark Keating at the Howard Hughes Medical Institute, University of Utah Health Sciences Center.  Dr. Wang joined the faculty at Baylor College of Medicine as an Assistant Professor (tenure track) in 1996 and Cleveland Clinic as Assistant Staff in 1999.  Dr. Wang has published more than 190 scientific papers and book chapters, and edited two volumes of Methods in Molecular Medicine.  He is an elected Fellow of the American Association for the Advancement of Science.  His research mostly focuses on finding genes for cardiovascular diseases, in particular, cardiac arrhythmias, syncope, seizures, and sudden death.  He also uses a variety of technologies to identify novel molecular mechanisms and develop therapies for diseases.

Steve  Archacki
Steve Archacki
Postdoctoral Fellow

Phone:(216) 445-0571

Susmita  Chakrabarti PhD
Susmita Chakrabarti PhD
Postdoctoral Fellow

Phone:(216) 445-0571

Qiuyun  Chen Ph.D.
Qiuyun Chen Ph.D.
Project Staff

Phone:(216) 444-2122

Hyosuk  Cho
Hyosuk Cho
Graduate Student

Phone:(216) 444-2122
Fax:(216) 636-1231

Yang  Guo
Yang Guo
Visting Scientist

Phone:(216) 445-0571

Yabo  Li
Yabo Li
Predoctoral Fellow

Phone:(216) 445-0571

Miroslava  Tischenko B.A.
Miroslava Tischenko B.A.
Senior Research Technologist

Phone:(216) 445-0571

Fan  Wang
Fan Wang
Research Associate

Phone:(216) 445-0571
laboratory web site

Zhijie  Wang
Zhijie Wang
Predoctoral Fellow

Phone:(215) 445-0571

Gang  Yu
Gang Yu
Predoctoral Fellow

Phone:(216) 445-0571


1: Zhou S, Wang H, Wang QK, Wang P, Wang F, Xu C. Loss of heterozygosity detected
at three short tandem repeat locus commonly used for human DNA identification in
a case of paternity testing. Leg Med (Tokyo). 2017 Jan;24:7-11. doi:
10.1016/j.legalmed.2016.11.001. PubMed PMID: 28081793.

2: Ye J, Yao Y, Song Q, Li S, Hu Z, Yu Y, Hu C, Da X, Li H, Chen Q, Wang QK.
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by
targeting p21 expression. Sci Rep. 2016 Oct 4;6:34034. doi: 10.1038/srep34034.
PubMed PMID: 27698442; PubMed Central PMCID: PMC5048429.

3: Xu C, Ma X, Zhang H, Zhang XX, Zhao JP, Ba HX, Rui-Du, Xing XM, Wang QK, Zhao
Q. Prevalence, risk factors and molecular characterization of Enterocytozoon
bieneusi in raccoon dogs (Nyctereutes procyonoides) in five provinces of Northern
China. Acta Trop. 2016 Sep;161:68-72. doi: 10.1016/j.actatropica.2016.05.015.
PubMed PMID: 27260667.

4: Zhang T, Yao Y, Wang J, Li Y, He P, Pasupuleti V, Hu Z, Jia X, Song Q, Tian
XL, Hu C, Chen Q, Wang QK. Haploinsufficiency of Klippel-Trenaunay syndrome gene
Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K
and AKT and disrupts vascular integrity by activating VE-cadherin. Hum Mol Genet.
2016 Aug 13. pii: ddw273. doi: 10.1093/hmg/ddw273. [Epub ahead of print] PubMed
PMID: 27522498.

5: Lu Q, Yao Y, Hu Z, Hu C, Song Q, Ye J, Xu C, Wang AZ, Chen Q, Wang QK.
Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic
Angiogenesis for Heart Disease. PLoS Biol. 2016 Aug 11;14(8):e1002529. doi:
10.1371/journal.pbio.1002529. PubMed PMID: 27513923; PubMed Central PMCID:

6: Luo C, Wang F, Qin S, Chen Q, Wang QK. Coronary artery disease susceptibility
gene ADTRP regulates cell cycle progression, proliferation, and apoptosis by
global gene expression regulation. Physiol Genomics. 2016 Aug 1;48(8):554-64.
doi: 10.1152/physiolgenomics.00028.2016. PubMed PMID: 27235449; PubMed Central
PMCID: PMC5005456.

7: Ke T, Han M, Zhao M, Wang QK, Zhang H, Zhao Y, Ruan X, Li H, Xu C, Sun T.
Alpha-actin-2 mutations in Chinese patients with a non-syndromatic thoracic
aortic aneurysm. BMC Med Genet. 2016 Jul 18;17(1):45. doi:
10.1186/s12881-016-0310-6. PubMed PMID: 27431987; PubMed Central PMCID:

8: Wang QK, Yang YZ, Li XY, Li K, Zhang D. Comparative ultrastructure of pretarsi
in five calyptrate species. Parasitol Res. 2016 Jun;115(6):2213-22. doi:
10.1007/s00436-016-4963-z. PubMed PMID: 26916893.

9: Huang Y, Wang Z, Liu Y, Xiong H, Zhao Y, Wu L, Yuan C, Wang L, Hou Y, Yu G,
Huang Z, Xu C, Chen Q, Wang QK. αB-Crystallin Interacts with Nav1.5 and Regulates
Ubiquitination and Internalization of Cell Surface Nav1.5. J Biol Chem. 2016 May
20;291(21):11030-41. doi: 10.1074/jbc.M115.695080. PubMed PMID: 26961874; PubMed
Central PMCID: PMC4900253.

10: Fan Q, Nie S, Li S, Liao Y, Zhang H, Zha L, Wang F, Tang T, Xia N, Xu C, Wang
P, Xie T, Xie J, Lu Q, Li Q, Qian J, Li B, Wu G, Wu Y, Yang Y, Wang QK, Tu X,
Cheng X. Analysis of the genetic association between IL27 variants and coronary
artery disease in a Chinese Han population. Sci Rep. 2016 May 12;6:25782. doi:
10.1038/srep25782. PubMed PMID: 27174010; PubMed Central PMCID: PMC4865940.

11: Chen S, Wang X, Wang J, Zhao Y, Wang D, Tan C, Fa J, Zhang R, Wang F, Xu C,
Huang Y, Li S, Yin D, Xiong X, Li X, Chen Q, Tu X, Yang Y, Xia Y, Xu C, Wang QK.
Genomic variant in CAV1 increases susceptibility to coronary artery disease and
myocardial infarction. Atherosclerosis. 2016 Mar;246:148-56. doi:
10.1016/j.atherosclerosis.2016.01.008. PubMed PMID: 26775120; PubMed Central
PMCID: PMC4764411.

12: Zhou J, Wang L, Zuo M, Wang X, Ahmed AS, Chen Q, Wang QK. Cardiac sodium
channel regulator MOG1 regulates cardiac morphogenesis and rhythm. Sci Rep. 2016
Feb 23;6:21538. doi: 10.1038/srep21538. PubMed PMID: 26903377; PubMed Central
PMCID: PMC4763225.

13: Wang C, Wu M, Qian J, Li B, Tu X, Xu C, Li S, Chen S, Zhao Y, Huang Y, Shi L,
Cheng X, Liao Y, Chen Q, Xia Y, Yao W, Wu G, Cheng M, Wang QK. Identification of
rare variants in TNNI3 with atrial fibrillation in a Chinese GeneID population.
Mol Genet Genomics. 2016 Feb;291(1):79-92. doi: 10.1007/s00438-015-1090-y. PubMed
PMID: 26169204; PubMed Central PMCID: PMC4713376.

14: Zhao Y, Huang Y, Li W, Wang Z, Zhan S, Zhou M, Yao Y, Zeng Z, Hou Y, Chen Q,
Tu X, Wang QK, Huang Z. Post-transcriptional regulation of cardiac sodium channel
gene SCN5A expression and function by miR-192-5p. Biochim Biophys Acta. 2015
Oct;1852(10 Pt A):2024-34. doi: 10.1016/j.bbadis.2015.07.016. PubMed PMID:
26209011; PubMed Central PMCID: PMC4757900.

15: Hao J, Han MJ, Han S, Meng X, Su TL, Wang QK. SERS detection of arsenic in
water: A review. J Environ Sci (China). 2015 Oct 1;36:152-62. doi:
10.1016/j.jes.2015.05.013. Review. PubMed PMID: 26456617.

16: Huang Y, Wang C, Yao Y, Zuo X, Chen S, Xu C, Zhang H, Lu Q, Chang L, Wang F,
Wang P, Zhang R, Hu Z, Song Q, Yang X, Li C, Li S, Zhao Y, Yang Q, Yin D, Wang X,
Si W, Li X, Xiong X, Wang D, Huang Y, Luo C, Li J, Wang J, Chen J, Wang L, Wang
L, Han M, Ye J, Chen F, Liu J, Liu Y, Wu G, Yang B, Cheng X, Liao Y, Wu Y, Ke T,
Chen Q, Tu X, Elston R, Rao S, Yang Y, Xia Y, Wang QK. Molecular Basis of
Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS
Gene-Gene Interaction Involved in Atrial Fibrillation. PLoS Genet. 2015 Aug
12;11(8):e1005393. doi: 10.1371/journal.pgen.1005393. PubMed PMID: 26267381;
PubMed Central PMCID: PMC4534423.

17: Wang P, Xu C, Wang C, Wu Y, Wang D, Chen S, Zhao Y, Wang X, Li S, Yang Q,
Zeng Q, Tu X, Liao Y, Wang QK, Cheng X. Association of SNP Rs9943582 in APLNR
with Left Ventricle Systolic Dysfunction in Patients with Coronary Artery Disease
in a Chinese Han GeneID Population. PLoS One. 2015 May 19;10(5):e0125926. doi:
10.1371/journal.pone.0125926. PubMed PMID: 25993436; PubMed Central PMCID:

18: Chen S, Wang C, Wang X, Xu C, Wu M, Wang P, Tu X, Wang QK. Significant
Association Between CAV1 Variant rs3807989 on 7p31 and Atrial Fibrillation in a
Chinese Han Population. J Am Heart Assoc. 2015 May 7;4(5). pii: e001980. doi:
10.1161/JAHA.115.001980. PubMed PMID: 25953654; PubMed Central PMCID: PMC4599427.

19: He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai
J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho
MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z,
Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo
M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y,
Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang
L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M,
Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z,
Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L.
Meta-analysis of genome-wide association studies of adult height in East Asians
identifies 17 novel loci. Hum Mol Genet. 2015 Mar 15;24(6):1791-800. doi:
10.1093/hmg/ddu583. PubMed PMID: 25429064; PubMed Central PMCID: PMC4351379.

20: Hao J, Han MJ, Meng X, Weimer W, Wang QK. Surface-enhanced Raman scattering
of perchlorate on cationic-modified silver nanofilms - Effect of inorganic
anions. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt C:1593-9. doi:
10.1016/j.saa.2014.10.052. PubMed PMID: 25459720.

21: Guo X, Xie HJ, Zheng JW, Xu H, Wang QK, Li YQ, Lee ST, Tang JX. The synthesis
of multi-structured SnS nanocrystals toward enhanced performance for photovoltaic
devices. Nanoscale. 2015 Jan 21;7(3):867-71. doi: 10.1039/c4nr04933k. PubMed
PMID: 25341192.

22: Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C,
Volpi S, Li Z, Sanal O, Mansouri D, Tezcan I, Rice GI, Chen C, Mansouri N,
Mahdaviani SA, Itan Y, Boisson B, Okada S, Zeng L, Wang X, Jiang H, Liu W, Han T,
Liu D, Ma T, Wang B, Liu M, Liu JY, Wang QK, Yalnizoglu D, Radoshevich L, Uzé G,
Gros P, Rozenberg F, Zhang SY, Jouanguy E, Bustamante J, García-Sastre A, Abel L,
Lebon P, Notarangelo LD, Crow YJ, Boisson-Dupuis S, Casanova JL, Pellegrini S.
Human intracellular ISG15 prevents interferon-α/β over-amplification and
auto-inflammation. Nature. 2015 Jan 1;517(7532):89-93. doi: 10.1038/nature13801.
PubMed PMID: 25307056; PubMed Central PMCID: PMC4303590.

23: An LH, Zheng BH, Liu RZ, Fan Q, Wang QK, Luo YF. Transcriptomic response to
estrogen exposure in the male Zhikong scallop, Chlamys farreri. Mar Pollut Bull.
2014 Dec 15;89(1-2):59-66. doi: 10.1016/j.marpolbul.2014.10.035. PubMed PMID:

24: Gao H, Li L, Rao S, Shen G, Xi Q, Chen S, Zhang Z, Wang K, Ellis SG, Chen Q,
Topol EJ, Wang QK. Genome-wide linkage scan identifies two novel genetic loci for
coronary artery disease: in GeneQuest families. PLoS One. 2014 Dec
8;9(12):e113935. doi: 10.1371/journal.pone.0113935. PubMed PMID: 25485937; PubMed
Central PMCID: PMC4259362.

25: Xu C, Yang Q, Xiong H, Wang L, Cai J, Wang F, Li S, Chen J, Wang C, Wang D,
Xiong X, Wang P, Zhao Y, Wang X, Huang Y, Chen S, Yin D, Li X, Liu Y, Liu J, Wang
J, Li H, Ke T, Ren X, Wu Y, Wu G, Wan J, Zhang R, Wu T, Wang J, Xia Y, Yang Y,
Cheng X, Liao Y, Chen Q, Zhou Y, He Q, Tu X, Wang QK. Candidate pathway-based
genome-wide association studies identify novel associations of genomic variants
in the complement system associated with coronary artery disease. Circ Cardiovasc
Genet. 2014 Dec;7(6):887-94. doi: 10.1161/CIRCGENETICS.114.000738. PubMed PMID:
25249547; PubMed Central PMCID: PMC4270888.

26: Wang RB, Wang QK, Xie HJ, Xu LH, Duhm S, Li YQ, Tang JX. HATCN-based charge
recombination layers as effective interconnectors for tandem organic solar cells.
ACS Appl Mater Interfaces. 2014 Sep 10;6(17):15604-9. doi: 10.1021/am504620x.
PubMed PMID: 25141159.

27: Shen GQ, Girelli D, Li L, Rao S, Archacki S, Olivieri O, Martinelli N, Park
JE, Chen Q, Topol EJ, Wang QK. A novel molecular diagnostic marker for familial
and early-onset coronary artery disease and myocardial infarction in the LRP8
gene. Circ Cardiovasc Genet. 2014 Aug;7(4):514-20. doi:
10.1161/CIRCGENETICS.113.000321. PubMed PMID: 24867879; PubMed Central PMCID:

28: Wang QK, Yang YZ, Liu MQ, Zhang D. Fine structure of Delia platura (Meigen)
(Diptera: Anthomyiidae) revealed by scanning electron microscopy. Microsc Res
Tech. 2014 Aug;77(8):619-30. doi: 10.1002/jemt.22380. PubMed PMID: 24854679.

29: Wang AN, Wang QK, Yang M, Hu J, Dong L, Xu JN. Experimental study on
malignant transformation of human bronchial epithelial cells induced by glycidyl
methacrylate and analysis on its methylation. Biomed Environ Sci. 2014
Jul;27(7):523-30. doi: 10.3967/bes2014.002. PubMed PMID: 25073911.

30: Zhang D, Liu XH, Wang QK, Li K. Sensilla on the antenna of blow fly,
Triceratopyga calliphoroides Rohdendorf (Diptera: Calliphoridae). Parasitol Res.
2014 Jul;113(7):2577-86. doi: 10.1007/s00436-014-3909-6. PubMed PMID: 24777341.

31: Xu Y, Zhou M, Wang J, Zhao Y, Li S, Zhou B, Su Z, Xu C, Xia Y, Qian H, Tu X,
Xiao W, Chen X, Chen Q, Wang QK. Role of microRNA-27a in down-regulation of
angiogenic factor AGGF1 under hypoxia associated with high-grade bladder
urothelial carcinoma. Biochim Biophys Acta. 2014 May;1842(5):712-25. doi:
10.1016/j.bbadis.2014.01.007. PubMed PMID: 24462738.

32: Xiong X, Xu C, Zhang Y, Li X, Wang B, Wang F, Yang Q, Wang D, Wang X, Li S,
Chen S, Zhao Y, Yin D, Huang Y, Zhu X, Wang L, Wang L, Chang L, Xu C, Li H, Ke T,
Ren X, Wu Y, Zhang R, Wu T, Xia Y, Yang Y, Ma X, Tu X, Wang QK. BRG1 variant
rs1122608 on chromosome 19p13.2 confers protection against stroke and regulates
expression of pre-mRNA-splicing factor SFRS3. Hum Genet. 2014 May;133(5):499-508.
doi: 10.1007/s00439-013-1389-x. PubMed PMID: 24190014; PubMed Central PMCID:

33: Wang QK, Liu XH, Lu PF, Zhang D. Ultrastructure of antennal sensilla in
Hydrotaea armipes (Fallén) (Diptera: Muscidae): new evidence for taxonomy of the
genus Hydrotaea. Zootaxa. 2014 Apr 23;3790:577-86. doi:
10.11646/zootaxa.3790.4.6. PubMed PMID: 24869889.

34: Su Z, Si W, Li L, Zhou B, Li X, Xu Y, Xu C, Jia H, Wang QK. MiR-144 regulates
hematopoiesis and vascular development by targeting meis1 during zebrafish
development. Int J Biochem Cell Biol. 2014 Apr;49:53-63. doi:
10.1016/j.biocel.2014.01.005. PubMed PMID: 24448023.

35: Bai Y, Nie S, Jiang G, Zhou Y, Zhou M, Zhao Y, Li S, Wang F, Lv Q, Huang Y,
Yang Q, Li Q, Li Y, Xia Y, Liu Y, Liu J, Qian J, Li B, Wu G, Wu Y, Wang B, Cheng
X, Yang Y, Ke T, Li H, Ren X, Ma X, Liao Y, Xu C, Tu X, Wang QK. Regulation of
CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism
rs2043211 (p.C10X) with ischemic stroke. Stroke. 2014 Feb;45(2):383-8. doi:
10.1161/STROKEAHA.113.003393. PubMed PMID: 24385277; PubMed Central PMCID:

36: Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK. Aggf1 acts at the top of
the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish.
Blood. 2014 Jan 23;123(4):501-8. doi: 10.1182/blood-2013-07-514612. PubMed PMID:
24277077; PubMed Central PMCID: PMC3901065.

37: Zhou J, Li Y, Wang QK, Pollak AN, Slobogean GP. Status of road safety and
injury burden: China. J Orthop Trauma. 2014;28 Suppl 1:S41-2. doi:
10.1097/BOT.0000000000000111. PubMed PMID: 24857998.

38: Li X, Huang Y, Yin D, Wang D, Xu C, Wang F, Yang Q, Wang X, Li S, Chen S,
Xiong X, Huang Y, Zhao Y, Wang L, Zhu X, Su Z, Zhou B, Zhang Y, Wang L, Chang L,
Xu C, Li H, Ke T, Ren X, Cheng X, Yang Y, Liao Y, Tu X, Wang QK. Meta-analysis
identifies robust association between SNP rs17465637 in MIA3 on chromosome 1q41
and coronary artery disease. Atherosclerosis. 2013 Nov;231(1):136-40. doi:
10.1016/j.atherosclerosis.2013.08.031. PubMed PMID: 24125424.

39: Tu X, Nie S, Liao Y, Zhang H, Fan Q, Xu C, Bai Y, Wang F, Ren X, Tang T, Xia
N, Li S, Huang Y, Liu J, Yang Q, Zhao Y, Lv Q, Li Q, Li Y, Xia Y, Qian J, Li B,
Wu G, Wu Y, Yang Y, Wang QK, Cheng X. The IL-33-ST2L pathway is associated with
coronary artery disease in a Chinese Han population. Am J Hum Genet. 2013 Oct
3;93(4):652-60. doi: 10.1016/j.ajhg.2013.08.009. Erratum in: Am J Hum Genet. 2014
Feb 6;94(2):311. PubMed PMID: 24075188; PubMed Central PMCID: PMC3791271.

40: Fu ZH, Xu JN, Yu WL, Wang QK, Wang AN, Tan F. [Method for determining
brodifacoum in workplace air by high-performance liquid chromatography]. Zhonghua
Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 Aug;31(8):625-6. Chinese. PubMed
PMID: 24053969.

41: Xu JN, Fu ZH, Yu WL, Wang QK, Tan F. Establishment of occupational exposure
limit for warfarin in China. Biomed Environ Sci. 2013 Jun;26(6):513-6. doi:
10.3967/0895-3988.2013.06.015. PubMed PMID: 23816588.

42: Zhang D, Wang QK, Liu XH, Li K. Sensilla on antenna and maxillary palp of
predaceous fly, Lispe neimongola Tian et Ma (Diptera: Muscidae). Micron. 2013
Jun;49:33-9. doi: 10.1016/j.micron.2013.02.012. PubMed PMID: 23548669.

43: Zhang D, Wang QK, Yang YZ, Chen YO, Li K. Sensory organs of the antenna of
two Fannia species (Diptera: Fanniidae). Parasitol Res. 2013 Jun;112(6):2177-85.
doi: 10.1007/s00436-013-3377-4. PubMed PMID: 23494158.

44: Shen GQ, Girelli D, Li L, Olivieri O, Martinelli N, Chen Q, Topol EJ, Wang
QK. Multi-allelic haplotype association identifies novel information different
from single-SNP analysis: a new protective haplotype in the LRP8 gene is against
familial and early-onset CAD and MI. Gene. 2013 May 25;521(1):78-81. doi:
10.1016/j.gene.2013.03.022. PubMed PMID: 23524007; PubMed Central PMCID:

45: Chakrabarti S, Wu X, Yang Z, Wu L, Yong SL, Zhang C, Hu K, Wang QK, Chen Q.
MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and
sick sinus syndrome. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):392-401. doi:
10.1161/CIRCEP.111.000206. PubMed PMID: 23420830; PubMed Central PMCID:

46: Chan K, Patel RS, Newcombe P, Nelson CP, Qasim A, Epstein SE, Burnett S,
Vaccarino VL, Zafari AM, Shah SH, Anderson JL, Carlquist JF, Hartiala J, Allayee
H, Hinohara K, Lee BS, Erl A, Ellis KL, Goel A, Schaefer AS, El Mokhtari NE,
Goldstein BA, Hlatky MA, Go AS, Shen GQ, Gong Y, Pepine C, Laxton RC, Whittaker
JC, Tang WH, Johnson JA, Wang QK, Assimes TL, Nöthlings U, Farrall M, Watkins H,
Richards AM, Cameron VA, Muendlein A, Drexel H, Koch W, Park JE, Kimura A, Shen
WF, Simpson IA, Hazen SL, Horne BD, Hauser ER, Quyyumi AA, Reilly MP, Samani NJ,
Ye S. Association between the chromosome 9p21 locus and angiographic coronary
artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol. 2013 Mar
5;61(9):957-70. doi: 10.1016/j.jacc.2012.10.051. PubMed PMID: 23352782; PubMed
Central PMCID: PMC3653306.

47: Liu Y, Wang DK, Jiang DZ, Qin X, Xie ZD, Wang QK, Liu M, Chen LM. Cloning and
functional characterization of novel variants and tissue-specific expression of
alternative amino and carboxyl termini of products of slc4a10. PLoS One.
2013;8(2):e55974. doi: 10.1371/journal.pone.0055974. PubMed PMID: 23409100;
PubMed Central PMCID: PMC3567025.

48: Timur AA, Murugesan G, Zhang L, Aung PP, Barnard J, Wang QK, Gaussem P,
Silverstein RL, Bhatt DL, Kottke-Marchant K. P2RY1 and P2RY12 polymorphisms and
on-aspirin platelet reactivity in patients with coronary artery disease. Int J
Lab Hematol. 2012 Oct;34(5):473-83. doi: 10.1111/j.1751-553X.2012.01420.x. PubMed
PMID: 22574824; PubMed Central PMCID: PMC3419334.

49: Wang QK, Zhang M, Li K, Zhang D. Olfactory sensilla on antennae and maxillary
palps of Fannia hirticeps (Stein, 1892) (Diptera: Fanniidae). Microsc Res Tech.
2012 Oct;75(10):1313-20. doi: 10.1002/jemt.22066. PubMed PMID: 22556028.

50: Zhang D, Wang QK, Hu DF, Li K. Cuticular structures on antennae of the bot
fly, Portschinskia magnifica (Diptera: Oestridae). Parasitol Res. 2012
Oct;111(4):1651-9. PubMed PMID: 22777702.

51: Zhang D, Wang QK, Hu DF, Li K. Sensilla on the antennal funiculus of the
horse stomach bot fly, Gasterophilus nigricornis. Med Vet Entomol. 2012
Sep;26(3):314-22. doi: 10.1111/j.1365-2915.2011.01007.x. PubMed PMID: 22276803.

52: Hu J, Wang QK, Wang AN, Dong L, Xu JN. [Methylation status of P16 gene during
malignant transformation of human bronchial epithelial cells induced by glycidyl
methacrylate]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2012
Jul;30(7):521-3. Chinese. PubMed PMID: 22931820.

53: Shen GQ, Li L, Wang QK. Genetic variant R952Q in LRP8 is associated with
increased plasma triglyceride levels in patients with early-onset CAD and MI. Ann
Hum Genet. 2012 May;76(3):193-9. doi: 10.1111/j.1469-1809.2012.00705.x. PubMed
PMID: 22404453.

54: Archacki SR, Angheloiu G, Moravec CS, Liu H, Topol EJ, Wang QK. Comparative
gene expression analysis between coronary arteries and internal mammary arteries
identifies a role for the TES gene in endothelial cell functions relevant to
coronary artery disease. Hum Mol Genet. 2012 Mar 15;21(6):1364-73. doi:
10.1093/hmg/ddr574. PubMed PMID: 22156939.

55: Wang C, Li Y, Shi L, Ren J, Patti M, Wang T, de Oliveira JR, Sobrido MJ,
Quintáns B, Baquero M, Cui X, Zhang XY, Wang L, Xu H, Wang J, Yao J, Dai X, Liu
J, Zhang L, Ma H, Gao Y, Ma X, Feng S, Liu M, Wang QK, Forster IC, Zhang X, Liu
JY. Mutations in SLC20A2 link familial idiopathic basal ganglia calcification
with phosphate homeostasis. Nat Genet. 2012 Feb 12;44(3):254-6. doi:
10.1038/ng.1077. PubMed PMID: 22327515.

56: Fu ZH, Wang QK, Yu WL, Wang J, Wang AN, Xu JN. [Determination of brodifacoum
in rat plasma by HPLC]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2012
Feb;30(2):135-6. Chinese. PubMed PMID: 22808549.

57: Cui X, Zeng F, Liu Y, Zhang J, Archacki S, Zhan T, Du R, Tang Z, Liu J, Wang
QK, Liu M. A novel SCN1A missense mutation causes generalized epilepsy with
febrile seizures plus in a Chinese family. Neurosci Lett. 2011 Sep
26;503(1):27-30. doi: 10.1016/j.neulet.2011.08.001. PubMed PMID: 21843600.

58: Yang Q, Li L, Chen Q, Foldvary-Schaefer N, Ondo WG, Wang QK. Association
studies of variants in MEIS1, BTBD9, and MAP2K5/SKOR1 with restless legs syndrome
in a US population. Sleep Med. 2011 Sep;12(8):800-4. doi:
10.1016/j.sleep.2011.06.006. PubMed PMID: 21925394; PubMed Central PMCID:

59: Wang AZ, Li L, Zhang B, Shen GQ, Wang QK. Association of SNP rs17465637 on
chromosome 1q41 and rs599839 on 1p13.3 with myocardial infarction in an American
caucasian population. Ann Hum Genet. 2011 Jul;75(4):475-82. doi:
10.1111/j.1469-1809.2011.00646.x. PubMed PMID: 21463265; PubMed Central PMCID:

60: Ding H, Tu X, Xu Y, Xu C, Wang X, Cui G, Bao X, Hui R, Wang QK, Wang DW. No
evidence for association of 12p13 SNPs rs11833579 and rs12425791 within NINJ2
gene with ischemic stroke in Chinese Han population. Atherosclerosis. 2011
Jun;216(2):381-2. doi: 10.1016/j.atherosclerosis.2011.02.005. PubMed PMID:

61: Xu Z, Li Y, Zhang X, Zeng F, Yuan M, Liu M, Wang QK, Liu JY. Identification
and molecular characterization of two novel mutations in COL1A2 in two Chinese
families with osteogenesis imperfecta. J Genet Genomics. 2011 Apr
20;38(4):149-56. doi: 10.1016/j.jgg.2011.03.002. PubMed PMID: 21530898.

62: Wang QK. [Responses of forest soil carbon pool and carbon cycle to the
changes of carbon input]. Ying Yong Sheng Tai Xue Bao. 2011 Apr;22(4):1075-81.
Review. Chinese. PubMed PMID: 21774335.

63: Wang F, Xu CQ, He Q, Cai JP, Li XC, Wang D, Xiong X, Liao YH, Zeng QT, Yang
YZ, Cheng X, Li C, Yang R, Wang CC, Wu G, Lu QL, Bai Y, Huang YF, Yin D, Yang Q,
Wang XJ, Dai DP, Zhang RF, Wan J, Ren JH, Li SS, Zhao YY, Fu FF, Huang Y, Li QX,
Shi SW, Lin N, Pan ZW, Li Y, Yu B, Wu YX, Ke YH, Lei J, Wang N, Luo CY, Ji LY,
Gao LJ, Li L, Liu H, Huang EW, Cui J, Jia N, Ren X, Li H, Ke T, Zhang XQ, Liu JY,
Liu MG, Xia H, Yang B, Shi LS, Xia YL, Tu X, Wang QK. Genome-wide association
identifies a susceptibility locus for coronary artery disease in the Chinese Han
population. Nat Genet. 2011 Mar 6;43(4):345-9. doi: 10.1038/ng.783. PubMed PMID:

64: Zhang T, Yong SL, Drinko JK, Popović ZB, Shryock JC, Belardinelli L, Wang QK.
LQTS mutation N1325S in cardiac sodium channel gene SCN5A causes cardiomyocyte
apoptosis, cardiac fibrosis and contractile dysfunction in mice. Int J Cardiol.
2011 Mar 3;147(2):239-45. doi: 10.1016/j.ijcard.2009.08.047. PubMed PMID:
19762097; PubMed Central PMCID: PMC2891203.

65: Li C, Wang F, Yang Y, Fu F, Xu C, Shi L, Li S, Xia Y, Wu G, Cheng X, Liu H,
Wang C, Wang P, Hao J, Ke Y, Zhao Y, Liu M, Zhang R, Gao L, Yu B, Zeng Q, Liao Y,
Yang B, Tu X, Wang QK. Significant association of SNP rs2106261 in the ZFHX3 gene
with atrial fibrillation in a Chinese Han GeneID population. Hum Genet. 2011
Mar;129(3):239-46. doi: 10.1007/s00439-010-0912-6. PubMed PMID: 21107608; PubMed
Central PMCID: PMC5069458.

66: Yang Q, Li L, Yang R, Shen GQ, Chen Q, Foldvary-Schaefer N, Ondo WG, Wang QK.
Family-based and population-based association studies validate PTPRD as a risk
factor for restless legs syndrome. Mov Disord. 2011 Feb 15;26(3):516-9. doi:
10.1002/mds.23459. PubMed PMID: 21264940; PubMed Central PMCID: PMC3895410.

67: Cheng X, Shi L, Nie S, Wang F, Li X, Xu C, Wang P, Yang B, Li Q, Pan Z, Li Y,
Xia H, Zheng C, Ke Y, Wu Y, Tang T, Yan X, Yang Y, Xia N, Yao R, Wang B, Ma X,
Zeng Q, Tu X, Liao Y, Wang QK. The same chromosome 9p21.3 locus is associated
with type 2 diabetes and coronary artery disease in a Chinese Han population.
Diabetes. 2011 Feb;60(2):680-4. doi: 10.2337/db10-0185. PubMed PMID: 21270277;
PubMed Central PMCID: PMC3028370.

68: Ouyang P, Saarel E, Bai Y, Luo C, Lv Q, Xu Y, Wang F, Fan C, Younoszai A,
Chen Q, Tu X, Wang QK. A de novo mutation in NKX2.5 associated with atrial septal
defects, ventricular noncompaction, syncope and sudden death. Clin Chim Acta.
2011 Jan 14;412(1-2):170-5. doi: 10.1016/j.cca.2010.09.035. PubMed PMID:
20932824; PubMed Central PMCID: PMC2998397.

69: Gao Y, Yang K, Xu S, Wang C, Liu J, Zhang Z, Yuan M, Luo X, Liu M, Wang QK,
Liu JY. Identification of compound heterozygous mutations in GNPTG in three
siblings of a Chinese family with mucolipidosis type III gamma. Mol Genet Metab.
2011 Jan;102(1):107-9. doi: 10.1016/j.ymgme.2010.09.007. PubMed PMID: 20951619.

70: Liu H, Liu W, Liao Y, Cheng L, Liu Q, Ren X, Shi L, Tu X, Wang QK, Guo AY.
CADgene: a comprehensive database for coronary artery disease genes. Nucleic
Acids Res. 2011 Jan;39(Database issue):D991-6. doi: 10.1093/nar/gkq1106. PubMed
PMID: 21045063; PubMed Central PMCID: PMC3013698.

71: Zhou L, Ding H, Zhang X, He M, Huang S, Xu Y, Shi Y, Cui G, Cheng L, Wang QK,
Hu FB, Wang D, Wu T. Genetic variants at newly identified lipid loci are
associated with coronary heart disease in a Chinese Han population. PLoS One.
2011;6(11):e27481. doi: 10.1371/journal.pone.0027481. PubMed PMID: 22110658;
PubMed Central PMCID: PMC3215720.

72: Wang QK, Huang XL, Zhang YQ, Song Y. [Treatment in 50 cases of pulmonary
embolism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Jan;23(1):46-7. Chinese.
PubMed PMID: 21251368.

73: Dai X, Gao Y, Xu Z, Cui X, Liu J, Li Y, Xu H, Liu M, Wang QK, Liu JY.
Identification of a novel genetic locus on chromosome 8p21.1-q11.23 for
idiopathic basal ganglia calcification. Am J Med Genet B Neuropsychiatr Genet.
2010 Oct 5;153B(7):1305-10. doi: 10.1002/ajmg.b.31102. PubMed PMID: 20552677.

74: Wang QK, Guo M, Zhang YQ, Song Y. [Comparison of therapeutic efficacy between
fondaparinux and low molecular weight heparin for patients with acute coronary
syndrome]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Oct;22(10):628-31.
Chinese. PubMed PMID: 20977850.

75: Huang Y, Zhang J, Li C, Yang G, Liu M, Wang QK, Tang Z. Identification of a
novel homozygous nonsense mutation in EYS in a Chinese family with autosomal
recessive retinitis pigmentosa. BMC Med Genet. 2010 Aug 10;11:121. doi:
10.1186/1471-2350-11-121. PubMed PMID: 20696082; PubMed Central PMCID:

76: Yin W, Ye X, Shi L, Wang QK, Jin H, Wang P, Bian Z. TP63 gene mutations in
Chinese P63 syndrome patients. J Dent Res. 2010 Aug;89(8):813-7. doi:
10.1177/0022034510366804. PubMed PMID: 20410354.

77: Xu C, Wang F, Wang B, Li X, Li C, Wang D, Xiong X, Wang P, Lu Q, Wang X, Yang
Q, Yin D, Huang Y, Ji L, Wang N, Chen S, Cheng X, Liao Y, Ma X, Su D, Chen G, Xia
H, Shi L, Tu X, Wang QK. Minor allele C of chromosome 1p32 single nucleotide
polymorphism rs11206510 confers risk of ischemic stroke in the Chinese Han
population. Stroke. 2010 Aug;41(8):1587-92. doi: 10.1161/STROKEAHA.110.583096.
PubMed PMID: 20576952.

78: Wang P, Yang Q, Wu X, Yang Y, Shi L, Wang C, Wu G, Xia Y, Yang B, Zhang R, Xu
C, Cheng X, Li S, Zhao Y, Fu F, Liao Y, Fang F, Chen Q, Tu X, Wang QK. Functional
dominant-negative mutation of sodium channel subunit gene SCN3B associated with
atrial fibrillation in a Chinese GeneID population. Biochem Biophys Res Commun.
2010 Jul 16;398(1):98-104. doi: 10.1016/j.bbrc.2010.06.042. PubMed PMID:
20558140; PubMed Central PMCID: PMC3132081.

79: Yang M, Wang SL, Zhang WD, Wang QK. [Dynamics of biomass- and nutrient
accumulation in a Chinese-fir plantation]. Ying Yong Sheng Tai Xue Bao. 2010
Jul;21(7):1674-80. Chinese. PubMed PMID: 20879522.

80: Yang R, Li L, Seidelmann SB, Shen GQ, Sharma S, Rao S, Abdullah KG, Mackinlay
KG, Elston RC, Chen Q, Topol EJ, Wang QK. A genome-wide linkage scan identifies
multiple quantitative trait loci for HDL-cholesterol levels in families with
premature CAD and MI. J Lipid Res. 2010 Jun;51(6):1442-51. doi:
10.1194/jlr.M004325. PubMed PMID: 20075193; PubMed Central PMCID: PMC3035507.

81: Cui JC, Zhang BJ, Lin YC, Wang QK, Qian AD, Nakane A, Hu DL, Tong GZ.
Protective effect of glutathione S-transferase-fused mutant staphylococcal
enterotoxin C against Staphylococcus aureus-induced bovine mastitis. Vet Immunol
Immunopathol. 2010 May 15;135(1-2):64-70. doi: 10.1016/j.vetimm.2009.11.001.
PubMed PMID: 19959244.

82: Ren X, Xu C, Zhan C, Yang Y, Shi L, Wang F, Wang C, Xia Y, Yang B, Wu G, Wang
P, Li X, Wang D, Xiong X, Liu J, Liu Y, Liu M, Liu J, Tu X, Wang QK.
Identification of NPPA variants associated with atrial fibrillation in a Chinese
GeneID population. Clin Chim Acta. 2010 Apr 2;411(7-8):481-5. doi:
10.1016/j.cca.2009.12.019. PubMed PMID: 20064500.

83: Wu X, Wang QK, Gui L, Liu M, Zhang X, Jin R, Li W, Yan L, Du R, Wang Q, Zhu
J, Yang J. Identification of a new lamin A/C mutation in a Chinese family
affected with atrioventricular block as the prominent phenotype. J Huazhong Univ
Sci Technolog Med Sci. 2010 Feb;30(1):103-7. doi: 10.1007/s11596-010-0119-z.
PubMed PMID: 20155465.

84: Wang Q, Diao Y, Xu Z, Li X, Luo XP, Xu H, Ouyang P, Liu M, Hu Z, Wang QK, Liu
JY. Identification of a novel splicing mutation in the growth hormone
(GH)-releasing hormone receptor gene in a Chinese family with pituitary dwarfism.
Mol Cell Endocrinol. 2009 Dec 10;313(1-2):50-6. doi: 10.1016/j.mce.2009.08.021.
Erratum in: Mol Cell Endocrinol. 2010 Apr 12;317(1-2):168-9. PubMed PMID:

85: Shi L, Li C, Wang C, Xia Y, Wu G, Wang F, Xu C, Wang P, Li X, Wang D, Xiong
X, Bai Y, Liu M, Liu J, Ren X, Gao L, Wang B, Zeng Q, Yang B, Ma X, Yang Y, Tu X,
Wang QK. Assessment of association of rs2200733 on chromosome 4q25 with atrial
fibrillation and ischemic stroke in a Chinese Han population. Hum Genet. 2009
Dec;126(6):843-9. doi: 10.1007/s00439-009-0737-3. PubMed PMID: 19707791.

86: Wang QK, Pu SP, Cong YW, Li YN, Luan CF.
cis-Diammine(glycolato-κO,O)platinum(II). Acta Crystallogr Sect E Struct Rep
Online. 2009 Nov 28;65(Pt 12):m1687. doi: 10.1107/S1600536809049757. PubMed PMID:
21578692; PubMed Central PMCID: PMC2972061.

87: Ke T, Gomez CR, Mateus HE, Castano JA, Wang QK. Novel CACNA1S mutation causes
autosomal dominant hypokalemic periodic paralysis in a South American family. J
Hum Genet. 2009 Nov;54(11):660-4. doi: 10.1038/jhg.2009.92. PubMed PMID:

88: Li H, Zhan T, Li C, Liu M, Wang QK. Repression of MHC class I transcription
by HPV16E7 through interaction with a putative RXRbeta motif and NF-kappaB
cytoplasmic sequestration. Biochem Biophys Res Commun. 2009 Oct 16;388(2):383-8.
doi: 10.1016/j.bbrc.2009.08.019. PubMed PMID: 19665994.

89: Fan C, Chen Q, Wang QK. Functional role of transcriptional factor TBX5 in
pre-mRNA splicing and Holt-Oram syndrome via association with SC35. J Biol Chem.
2009 Sep 18;284(38):25653-63. doi: 10.1074/jbc.M109.041368. PubMed PMID:
19648116; PubMed Central PMCID: PMC2757967.

90: Fan C, Ouyang P, Timur AA, He P, You SA, Hu Y, Ke T, Driscoll DJ, Chen Q,
Wang QK. Novel roles of GATA1 in regulation of angiogenic factor AGGF1 and
endothelial cell function. J Biol Chem. 2009 Aug 28;284(35):23331-43. doi:
10.1074/jbc.M109.036079. PubMed PMID: 19556247; PubMed Central PMCID: PMC2749107.

91: Tang Z, Wang Z, Wang Z, Ke T, Wang QK, Liu M. Novel compound heterozygous
mutations in CERKL cause autosomal recessive retinitis pigmentosa in a
nonconsanguineous Chinese family. Arch Ophthalmol. 2009 Aug;127(8):1077-8. doi:
10.1001/archophthalmol.2009.207. PubMed PMID: 19667359.

92: Ye X, Shi L, Yin W, Meng L, Wang QK, Bian Z. Further evidence of genetic
heterogeneity segregating with hereditary gingival fibromatosis. J Clin
Periodontol. 2009 Aug;36(8):627-33. doi: 10.1111/j.1600-051X.2009.01438.x. PubMed
PMID: 19552635.

93: Wang QK, Fan B, Xu GB. [Soil active organic matter in broadleaved forest and
Chinese fir plantation in subtropical region of China]. Ying Yong Sheng Tai Xue
Bao. 2009 Jul;20(7):1536-42. Chinese. PubMed PMID: 19899448.

94: Martinelli N, Olivieri O, Shen GQ, Trabetti E, Pizzolo F, Busti F, Friso S,
Bassi A, Li L, Hu Y, Pignatti PF, Corrocher R, Wang QK, Girelli D. Additive
effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype
in modulating apolipoprotein E concentration and the risk of myocardial
infarction: a case-control study. BMC Med Genet. 2009 May 13;10:41. doi:
10.1186/1471-2350-10-41. PubMed PMID: 19439088; PubMed Central PMCID: PMC2689206.

95: Lü LJ, Jin YD, Zheng RY, Fan BH, Yang MX, Ying XM, Wang QK, Zhang WB. [The
observe of clinical effect of treating lumbar intervertebral disc herniation by
bone setting manipulation of different directions]. Zhongguo Gu Shang. 2009
Apr;22(4):255-8. Chinese. PubMed PMID: 19408748.

96: Yang M, Xu JN, Wang QK, Li Y, Sun JX, Li JY, Xie GY, Wang J. [Study on
malignant transformation of human bronchial epithelial cells induced by glycidyl
methacrylate]. Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Mar;43(3):187-92. Chinese.
PubMed PMID: 19534922.

97: Liu JZ, Yang T, Li X, Liu M, Wang QK, Liu JY. A novel mutation in the ATP2C1
gene is associated with Hailey-Hailey disease in a Chinese family. Int J
Dermatol. 2009 Jan;48(1):47-51. doi: 10.1111/j.1365-4632.2009.03878.x. Erratum
in: Int J Dermatol. 2009 May;48(5):554. Liu, Zhou Jiang [corrected to Liu, Jiang
Zhou]. PubMed PMID: 19126050.

98: Shen GQ, Abdullah KG, Wang QK. The TaqMan method for SNP genotyping. Methods
Mol Biol. 2009;578:293-306. doi: 10.1007/978-1-60327-411-1_19. PubMed PMID:

99: Xi Q, Li L, Traboulsi EI, Wang QK. Novel ABCA4 compound heterozygous
mutations cause severe progressive autosomal recessive cone-rod dystrophy
presenting as Stargardt disease. Mol Vis. 2009;15:638-45. PubMed PMID: 19352439;
PubMed Central PMCID: PMC2665199.

100: Zhang X, Chen S, Yoo S, Chakrabarti S, Zhang T, Ke T, Oberti C, Yong SL,
Fang F, Li L, de la Fuente R, Wang L, Chen Q, Wang QK. Mutation in nuclear pore
component NUP155 leads to atrial fibrillation and early sudden cardiac death.
Cell. 2008 Dec 12;135(6):1017-27. doi: 10.1016/j.cell.2008.10.022. PubMed PMID:

101: Dai XH, Chen WW, Wang X, Zhu QH, Li C, Li L, Liu MG, Wang QK, Liu JY. A
novel genetic locus for familial febrile seizures and epilepsy on chromosome
3q26.2-q26.33. Hum Genet. 2008 Nov;124(4):423-9. doi: 10.1007/s00439-008-0566-9.
PubMed PMID: 18830713.

102: Zhang X, Chen S, Zhang L, Liu M, Redfearn S, Bryant RM, Oberti C, Vincent
GM, Wang QK. Protective effect of KCNH2 single nucleotide polymorphism K897T in
LQTS families and identification of novel KCNQ1 and KCNH2 mutations. BMC Med
Genet. 2008 Sep 23;9:87. doi: 10.1186/1471-2350-9-87. PubMed PMID: 18808722;
PubMed Central PMCID: PMC2570672.

103: Hu Y, Li L, Seidelmann SB, Timur AA, Shen PH, Driscoll DJ, Wang QK.
Identification of association of common AGGF1 variants with susceptibility for
Klippel-Trenaunay syndrome using the structure association program. Ann Hum
Genet. 2008 Sep;72(Pt 5):636-43. doi: 10.1111/j.1469-1809.2008.00458.x. PubMed
PMID: 18564129; PubMed Central PMCID: PMC2602961.

104: Abdullah KG, Li L, Shen GQ, Hu Y, Yang Y, MacKinlay KG, Topol EJ, Wang QK.
Four SNPS on chromosome 9p21 confer risk to premature, familial CAD and MI in an
American Caucasian population (GeneQuest). Ann Hum Genet. 2008 Sep;72(Pt
5):654-7. doi: 10.1111/j.1469-1809.2008.00454.x. PubMed PMID: 18505420; PubMed
Central PMCID: PMC2634771.

105: Li RH, Wang SL, Wang QK. [Nutrient contents and resorption characteristics
in needles of different age Pinus massoniana (Lamb.) before and after withering].
Ying Yong Sheng Tai Xue Bao. 2008 Jul;19(7):1443-7. Chinese. PubMed PMID:

106: Liu P, Zhang S, Yao Q, Liu X, Wang X, Huang C, Huang X, Wang P, Yuan M, Liu
JY, Wang QK, Liu M. Identification of a genetic locus for autosomal dominant
disseminated superficial actinic porokeratosis on chromosome 1p31.3-p31.1. Hum
Genet. 2008 Jun;123(5):507-13. doi: 10.1007/s00439-008-0504-x. PubMed PMID:

107: Liu P, Yang Q, Wang X, Feng A, Yang T, Yang R, Wang P, Yuang M, Liu M, Liu
JY, Wang QK. Identification of a genetic locus for ichthyosis vulgaris on
chromosome 10q22.3-q24.2. J Invest Dermatol. 2008 Jun;128(6):1418-22. PubMed
PMID: 18079749.

108: Zhang S, Wang L, Hao Y, Wang P, Hao P, Yin K, Wang QK, Liu M. T14484C and
T14502C in the mitochondrial ND6 gene are associated with Leber's hereditary
optic neuropathy in a Chinese family. Mitochondrion. 2008 Jun;8(3):205-10. doi:
10.1016/j.mito.2008.02.003. PubMed PMID: 18440284.

109: Liu QQ, Oberti C, Zhang XQ, Ke T, Zhang T, Scheinman M, Hu DY, Wang QK. [A
Novel mutation of F189L in CASQ2 in families with catecholaminergic polymorphic
ventricular tachycardia]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008
Jun;25(3):334-7. Chinese. PubMed PMID: 18543230.

110: Li H, Li C, Lu Q, Su T, Ke T, Li DW, Yuan M, Liu J, Ren X, Zhang Z, Zeng S,
Wang QK, Liu M. Cataract mutation P20S of alphaB-crystallin impairs chaperone
activity of alphaA-crystallin and induces apoptosis of human lens epithelial
cells. Biochim Biophys Acta. 2008 May;1782(5):303-9. doi:
10.1016/j.bbadis.2008.01.011. PubMed PMID: 18343237.

111: Seidelmann SB, Li L, Shen GQ, Topol EJ, Wang QK. Identification of a novel
locus for triglyceride on chromosome 1p31-32 in families with premature CAD and
MI. J Lipid Res. 2008 May;49(5):1034-8. doi: 10.1194/jlr.M700576-JLR200. PubMed
PMID: 18245017; PubMed Central PMCID: PMC2311437.

112: Zhang S, Yin K, Ren X, Wang P, Zhang S, Cheng L, Yang J, Liu JY, Liu M, Wang
QK. Identification of a novel KCNQ1 mutation associated with both Jervell and
Lange-Nielsen and Romano-Ward forms of long QT syndrome in a Chinese family. BMC
Med Genet. 2008 Apr 9;9:24. doi: 10.1186/1471-2350-9-24. PubMed PMID: 18400097;
PubMed Central PMCID: PMC2322962.

113: Wu L, Yong SL, Fan C, Ni Y, Yoo S, Zhang T, Zhang X, Obejero-Paz CA, Rho HJ,
Ke T, Szafranski P, Jones SW, Chen Q, Wang QK. Identification of a new co-factor,
MOG1, required for the full function of cardiac sodium channel Nav 1.5. J Biol
Chem. 2008 Mar 14;283(11):6968-78. doi: 10.1074/jbc.M709721200. PubMed PMID:

114: Liu JY, Dai X, Sheng J, Cui X, Wang X, Jiang X, Tu X, Tang Z, Bai Y, Liu M,
Wang QK. Identification and functional characterization of a novel splicing
mutation in RP gene PRPF31. Biochem Biophys Res Commun. 2008 Mar 7;367(2):420-6.
doi: 10.1016/j.bbrc.2007.12.156. PubMed PMID: 18177735; PubMed Central PMCID:

115: Ren X, Liu JY, Zhai LY, Yao Q, Dai X, Cai Z, Liu P, Sun K, Huang C, Wang QK,
Liu M. A splicing mutation in the COL7A1 gene causes autosomal dominant
dystrophic epidermolysis bullosa pruriginosa. Br J Dermatol. 2008
Mar;158(3):618-20. PubMed PMID: 18067480.

116: Shen GQ, Li L, Rao S, Abdullah KG, Ban JM, Lee BS, Park JE, Wang QK. Four
SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus
that confers high cross-race risk for development of coronary artery disease.
Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):360-5. PubMed PMID: 18048766.

117: Shen GQ, Rao S, Martinelli N, Li L, Olivieri O, Corrocher R, Abdullah KG,
Hazen SL, Smith J, Barnard J, Plow EF, Girelli D, Wang QK. Association between
four SNPs on chromosome 9p21 and myocardial infarction is replicated in an
Italian population. J Hum Genet. 2008;53(2):144-50. PubMed PMID: 18066490.

118: Zhang S, Liu M, Dong JM, Yin K, Wang P, Bu J, Li J, Hao YS, Hao P, Wang QK,
Wang L. Identification of a genetic locus for autosomal dominant infantile
cataract on chromosome 20p12.1-p11.23 in a Chinese family. Mol Vis.
2008;14:1893-7. PubMed PMID: 18958302; PubMed Central PMCID: PMC2573730.

119: Shen GQ, Li L, Girelli D, Seidelmann SB, Rao S, Fan C, Park JE, Xi Q, Li J,
Hu Y, Olivieri O, Marchant K, Barnard J, Corrocher R, Elston R, Cassano J,
Henderson S, Hazen SL, Plow EF, Topol EJ, Wang QK. An LRP8 variant is associated
with familial and premature coronary artery disease and myocardial infarction. Am
J Hum Genet. 2007 Oct;81(4):780-91. PubMed PMID: 17847002; PubMed Central PMCID:

120: Chang W, Ding Q, Tang Z, Liu P, Jiang F, Ke T, Ren X, Wang Z, Liu J, Wang
QK, Liu M. A novel de novo frameshift mutation of RPGR ORF15 is associated with
X-linked retinitis pigmentosa in a Chinese family. Mol Vis. 2007 Aug
30;13:1548-54. PubMed PMID: 17893654.

121: Zhang X, Chen L, Liu J, Zhao Z, Qu E, Wang X, Chang W, Xu C, Wang QK, Liu M.
A novel DSPP mutation is associated with type II dentinogenesis imperfecta in a
Chinese family. BMC Med Genet. 2007 Aug 8;8:52. PubMed PMID: 17686168; PubMed
Central PMCID: PMC1995191.

122: Wu L, Archacki SR, Zhang T, Wang QK. Induction of high STAT1 expression in
transgenic mice with LQTS and heart failure. Biochem Biophys Res Commun. 2007 Jun
29;358(2):449-54. PubMed PMID: 17490620; PubMed Central PMCID: PMC3505674.

123: Wang QK, Wang SL, Yu XJ, Zhang J, Liu YX. [Effects of Cunninghamia
lanceolata-broadleaved tree species mixed leaf litters on active soil organic
matter]. Ying Yong Sheng Tai Xue Bao. 2007 Jun;18(6):1203-7. Chinese. PubMed
PMID: 17763716.

124: Zhang T, Yong SL, Tian XL, Wang QK. Cardiac-specific overexpression of SCN5A
gene leads to shorter P wave duration and PR interval in transgenic mice. Biochem
Biophys Res Commun. 2007 Apr 6;355(2):444-50. PubMed PMID: 17300750; PubMed
Central PMCID: PMC1885482.

125: Huang HL, Xu JN, Wang QK, Yang M, Wang YW, Chen Y, Li GL. [Association
between genetic polymorphisms of DNA repair genes XRCC1, XRCC3 and susceptibility
to chronic benzene poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi.
2007 Apr;25(4):193-6. Chinese. PubMed PMID: 17535647.

126: Xu JN, Huang HL, Wang QK, Wang YW, Yang M, Zheng YX. [Analysis for the
association between genetic polymorphisms of XRCC1, XPD, XRCC3, CCND1 and the
latency of the occupational chronic benzene poisoning]. Zhonghua Yu Fang Yi Xue
Za Zhi. 2007 Mar;41(2):114-7. Chinese. PubMed PMID: 17605237.

127: Tian XL, Cheng Y, Zhang T, Liao ML, Yong SL, Wang QK. Optical mapping of
ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S. Biochem Biophys
Res Commun. 2007 Jan 26;352(4):879-83. PubMed PMID: 17157817; PubMed Central
PMCID: PMC2699586.

128: Yong SL, Ni Y, Zhang T, Tester DJ, Ackerman MJ, Wang QK. Characterization of
the cardiac sodium channel SCN5A mutation, N1325S, in single murine ventricular
myocytes. Biochem Biophys Res Commun. 2007 Jan 12;352(2):378-83. PubMed PMID:
17118339; PubMed Central PMCID: PMC1773013.

129: Rao SQ, Xu LD, Zhang GM, Li X, Li L, Shen GQ, Jiang Y, Yang YY, Gong BS,
Jiang W, Zhang F, Xiao Y, Wang QK. Familial aggregation analysis of gene
expressions. BMC Proc. 2007;1 Suppl 1:S49. PubMed PMID: 18466548; PubMed Central
PMCID: PMC2367533.

130: Liu JY, Ren X, Yang X, Guo T, Yao Q, Li L, Dai X, Zhang M, Wang L, Liu M,
Wang QK. Identification of a novel GPR143 mutation in a large Chinese family with
congenital nystagmus as the most prominent and consistent manifestation. J Hum
Genet. 2007;52(6):565-70. PubMed PMID: 17516023.

131: Zhang X, Cao ZW, Lin ZX, Wang QK, Li YX. EMMA: an efficient massive mapping
algorithm using improved approximate mapping filtering. Acta Biochim Biophys Sin
(Shanghai). 2006 Dec;38(12):857-64. PubMed PMID: 17151779.

132: Topol EJ, Smith J, Plow EF, Wang QK. Genetic susceptibility to myocardial
infarction and coronary artery disease. Hum Mol Genet. 2006 Oct 15;15 Spec No
2:R117-23. Review. PubMed PMID: 16987874.

133: Wang X, Xiao F, Yang Q, Liang B, Tang Z, Jiang L, Zhu Q, Chang W, Jiang J,
Jiang C, Ren X, Liu JY, Wang QK, Liu M. A novel mutation in GDF5 causes autosomal
dominant symphalangism in two Chinese families. Am J Med Genet A. 2006 Sep
1;140A(17):1846-53. PubMed PMID: 16892395.

134: Ke T, Wang QK, Ji B, Wang X, Liu P, Zhang X, Tang Z, Ren X, Liu M. Novel
HSF4 mutation causes congenital total white cataract in a Chinese family. Am J
Ophthalmol. 2006 Aug;142(2):298-303. PubMed PMID: 16876512.

135: Liu M, Ke T, Wang Z, Yang Q, Chang W, Jiang F, Tang Z, Li H, Ren X, Wang X,
Wang T, Li Q, Yang J, Liu J, Wang QK. Identification of a CRYAB mutation
associated with autosomal dominant posterior polar cataract in a Chinese family.
Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3461-6. PubMed PMID: 16877416.

136: Huang HL, Xu JN, Wang QK, Wang YW, Yang M, Chen Y, Li GL. [Association
between polymorphisms of XPD gene and susceptibility to chronic benzene
poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 Jul;24(7):390-3.
Chinese. PubMed PMID: 16889696.

137: Luo L, Shen GQ, Stiffler KA, Wang QK, Pretlow TG, Pretlow TP. Loss of
heterozygosity in human aberrant crypt foci (ACF), a putative precursor of colon
cancer. Carcinogenesis. 2006 Jun;27(6):1153-9. PubMed PMID: 16474178.

138: Melamud A, Shen GQ, Chung D, Xi Q, Simpson E, Li L, Peachey NS, Zegarra H,
Hagstrom SA, Wang QK, Traboulsi EI. Mapping a new genetic locus for X linked
retinitis pigmentosa to Xq28. J Med Genet. 2006 Jun;43(6):e27. PubMed PMID:
16740911; PubMed Central PMCID: PMC2593026.

139: Wang QK, Rao XY, Li B. [Investigation and analysis for morbidity of
pneumoconiosis in Meizhou city from 1987 to 2004]. Zhonghua Lao Dong Wei Sheng
Zhi Ye Bing Za Zhi. 2006 Feb;24(2):113-4. Chinese. PubMed PMID: 16600120.

140: Li X, Rao S, Jiang W, Li C, Xiao Y, Guo Z, Zhang Q, Wang L, Du L, Li J, Li
L, Zhang T, Wang QK. Discovery of Time-Delayed Gene Regulatory Networks based on
temporal gene expression profiling. BMC Bioinformatics. 2006 Jan 18;7:26. PubMed
PMID: 16420705; PubMed Central PMCID: PMC1386718.

141: Liu JY, Ji MF, Wang XR, Luo RL, Ren X, Liu M, Wang QK. Detection of human
chromosomal abnormalities using a new technique combining
4',6-diamidino-2-phenyl-indole staining and image analysis. Clin Genet. 2006
Jan;69(1):65-71. PubMed PMID: 16451138.

142: Huang C, Yang Q, Ke T, Wang H, Wang X, Shen J, Tu X, Tian J, Liu JY, Wang
QK, Liu M. A novel de novo frame-shift mutation of the EDA gene in a Chinese Han
family with hypohidrotic ectodermal dysplasia. J Hum Genet. 2006;51(12):1133-7.
PubMed PMID: 17066260.

143: Liu M, Wang X, Cai Z, Tang Z, Cao K, Liang B, Ren X, Liu JY, Wang QK. A
novel heterozygous mutation in the Indian hedgehog gene (IHH) is associated with
brachydactyly type A1 in a Chinese family. J Hum Genet. 2006;51(8):727-31. PubMed
PMID: 16871364.

144: Yong SL, Wang QK. Animal models for cardiac arrhythmias. Methods Mol Med.
2006;129:127-48. PubMed PMID: 17085809.

145: Tian XL, Wang QK. Generation of transgenic mice for cardiovascular research.
Methods Mol Med. 2006;129:69-81. PubMed PMID: 17085805.

146: You SA, Wang QK. Proteomics with two-dimensional gel electrophoresis and
mass spectrometry analysis in cardiovascular research. Methods Mol Med.
2006;129:15-26. PubMed PMID: 17085802.

147: Archacki SR, Wang QK. Microarray analysis of cardiovascular diseases.
Methods Mol Med. 2006;129:1-13. PubMed PMID: 17085801.

148: Shen GQ, Luo A, Wang QK. High-throughput single-nucleotide polymorphisms
genotyping: TaqMan assay and pyrosequencing assay. Methods Mol Med.
2006;128:209-24. PubMed PMID: 17071998.

149: Rao S, Wang QK. SAGE programs: model-free linkage analysis for complex
cardiovascular phenotypes. Methods Mol Med. 2006;128:61-89. PubMed PMID:

150: Li L, Wang QK, Rao S. LINKAGE programs: linkage analysis for monogenic
cardiovascular diseases. Methods Mol Med. 2006;128:41-60. PubMed PMID: 17071989.

151: Timur AA, Wang QK. Construction of somatic cell hybrid lines: fusion of
mouse thymidine kinase-deficient 3T3 fibroblasts and human lymphoblastoid cells.
Methods Mol Med. 2006;128:33-40. PubMed PMID: 17071988.

152: Timur AA, Wang QK. Fluorescence in situ hybridization in cardiovascular
disease. Methods Mol Med. 2006;128:11-21. PubMed PMID: 17071986.

153: Du W, Bautista JF, Yang H, Diez-Sampedro A, You SA, Wang L, Kotagal P,
Lüders HO, Shi J, Cui J, Richerson GB, Wang QK. Calcium-sensitive potassium
channelopathy in human epilepsy and paroxysmal movement disorder. Nat Genet. 2005
Jul;37(7):733-8. PubMed PMID: 15937479.

154: Wang QK. Update on the molecular genetics of vascular anomalies. Lymphat Res
Biol. 2005;3(4):226-33. Review. PubMed PMID: 16379592; PubMed Central PMCID:

155: Xu JN, Wu CL, Chen Y, Wang QK, Li GL, Su Z. [Effect of the polymorphism of
myeloperoxidase gene on the risk of benzene poisoning]. Zhonghua Lao Dong Wei
Sheng Zhi Ye Bing Za Zhi. 2003 Apr;21(2):86-9. Chinese. PubMed PMID: 14761515.

156: Zhuang ZZ, Wang MD, Chen ZH, Jiang JX, Zou LF, Wang QK, Song YL, Li QH.
[Pharmacological effects of an extract of Panax notogienseng (Burk.) F H chen on
the heart (author's transl)]. Yao Xue Xue Bao. 1980 Jul;15(7):385-90. Chinese.
PubMed PMID: 7424525.