Molecular Medicine Faculty

  • Derek Abbott, M.D., Ph.D., CWRU, Pathology, signaling pathways responsible for NOD2-induced Crohn's Disease.
  • Jay Alberts, Ph.D., Biomedical Engineering, neural aspects of movement control and upper extremity function.
  • Micheala Aldred, Ph.D., Genomic Medicine Institute, chromosome deletions in development and cancer.
  • Alex Almasan, Ph.D., Cancer Biology, DNA damage responses, radiation-regulated genes, cell cycle control, and apoptosis.
  • Bela Anand-Apte, M.D., Ph.D., Ophthalmic Research, diabetic retinopathy and age-related macular degeneration.
  • Suneel Apte, M.B.B.S., D.Phil., Biomedical Engineering, extracellular matrix remodeling by metalloproteinases.
  • Mark Aronica, M.D., Medicine, synthesis and turnover of extracellular matrix in asthma.
  • Amiya Banerjee, Ph.D., Virology, gene expression of negative-strand RNA viruses.
  • John Barnard, Ph.D., Quantitative Health Sciences, statistical genetics, missing data problems, Bayesian statistics, bioinformatics and statistical computing.
  • Gerald Beck, Ph.D., Quantitative Health Sciences, data coordination for clinical trials (hemodialysis and dialysis access consortium).
  • Cornelia Bergmann, Ph.D., Neurosciences, regulation of and function of CD8 T cells during viral infections of the central nervous system (CNS) associated with demyelination.
  • Kathleen Berkner, Ph.D., Molecular Cardiology, carboxylation of vitamin K- dependent proteins.
  • Henry Boom, M.D., CWRU, Medicine, heterogeneity of T-cells in M. tuberculosis infection.
  • Ernest Borden, M.D., Cancer Biology, melanoma cancer therapies, interferons, vaccines, and antibodies.
  • Matthias Buck, Ph.D., CWRU, Physiology and Biophysics, molecular biophysics of small GTPase-protein interactions in neuronal cell signaling.
  • Tatiana Byzova, Ph.D., Molecular Cardiology, cell adhesion molecules/integrins in thrombosis, vascular biology and cancer.
  • Martha Cathcart, Ph.D., Cell Biology, monocyte signal transduction, activation, chronic inflammation.
  • Shu Chen, Ph.D., CWRU, Pathology, LRRK2: pathway to parkinson disease.
  • Xi Chen, Ph.D., Quantitative Health Sciences, high-throughput genomic data analysis, pharmacogenomics, genetic epidemiology and correlated data analysis.
  • Jianguo Cheng, M.D., Ph.D., Anesthesiology Research, interventional pain management and spinal cord stimulation.
  • Yuanna Cheng, M.D., Ph.D., Molecular Cardiology, cardiac arrhythmogenesis and remodeling following left ventricular reconstruction.
  • Guy Chisolm, Ph.D., Cell Biology, cellular effects of lipoprotein oxidation products on inflammation and atherosclerosis.
  • Peter Chumakov, M.D., Ph.D., Molecular Genetics, p53-dependent mechanisms of proliferation control and maintenance of genetic stability.
  • Peter Cohen, M.D., Surgery Research, immunotherapy
  • Clemencia Colmenares, Ph.D., Cancer Biology, role of c-ski proto-oncogene in growth and development.
  • John Crabb, Ph.D., Ophthalmic Research, biochemistry of vision in proteome changes associated with retinal degenerative diseases and the mammalian visual cycle.
  • Margot Damaser, Ph.D., Biomedical Engineering, soft-tissue biomechanics, incontinence and nerve regeneration.
  • Brian Davis, Ph.D., Biomedical Engineering, biomechanics of the lower extremities.
  • Carol de la Motte, Ph.D., Pathobiology, role of extracellular matrix to inflammatory cell recruitment and activation involved in diseases of the intestine and lung.
  • Kathleen Derwin, Ph.D., Biomedical Engineering, tendon mechanobiology and tissue engineering.
  • Paul DiCorleto, Ph.D., Cell Biology, Chair of Molecular Medicine, growth factors and atherosclerosis.
  • Donna Driscoll, Ph.D., Cell Biology, posttranscriptional regulation of gene expression, RNA structure and function.
  • Thomas Egelhoff, Ph.D., Cell Biology, mechanisms regulating cytoskeletal function during cell migration and cytokinesis.
  • Paul Elson, Sc.D., Quantitative Health Sciences, group-sequential methods and clinical trials.
  • Charis Eng, M.D., Ph.D., Genomic Medicine Institute, human cancer genomics, personalized medicine.
  • Serpil Erzurum, M.D., Pathobiology, airway inflammation, reactive oxygen and nitrogen species.
  • Rob Fairchild, Ph.D., Immunology, skin and cardiac allograft rejection, peripheral T lymphocyte recruitment.
  • Maria Febbraio, Ph.D., Cell Biology, scavenger receptors and atherosclerosis, fatty acid transport and metabolism.
  • Ariel Feldstein, M.D., Cell Biology, nonalcoholic fatty liver disease.
  • Jim Finke, Ph.D., Immunology, tumor immunity, T lymphocytes, signal transduction.
  • Claudio Fiocchi, M.D., Pathobiology, pathogenesis of inflammatory bowel disease and animal models of IBD.
  • Elizabeth Fisher, Ph.D., Biomedical Engineering, image analysis for monitoring of multiple sclerosis.
  • Aaron Fleischman, Ph.D., Biomedical Engineering, development of microelectromechanical systems (MEMS) technology for biomedical applications.
  • Joan Fox, Ph.D., Molecular Cardiology, molecular mechanisms by which stress induces cardiovascular disease.
  • Paul Fox, Ph.D., Cell Biology, RNA structure and regulation of translation.
  • Alex Zhenghong Fu, Ph.D., Quantitative Health Sciences, health economics, pharmacoeconomics, health outcome and health service research.
  • Kiyotaka Fukamachi, M.D., Ph.D., Biomedical Engineering, development of surgical devices for heart failure treatment.
  • Ram Ganapathi, Ph.D., Taussig Cancer Center, clinical pharmacology and experimental cancer chemotherapy.
  • Leonard Golding, M.D., Biomedical Engineering, devices for cardiac support and stabilization in heart failure.
  • Linda Graham, M.D., Biomedical Engineering, healing of prosthetic vascular grafts.
  • Neetu Gupta, Ph.D., Immunology, plasma membrane and actin cytoskeletal dynamics during B cell activation.
  • Stephanie Hagstrom, Ph.D., Ophthalmic Research, macular degeneration, retiniti's pigmentosa, and genetics of inherited retinal degeneration.
  • Thomas Hamilton, Ph.D., Immunology, inflammatory gene expression in mononuclear phagocytes.
  • Jaharul Haque, Ph.D., Cancer Biology, cytokine-mediated cell signaling in allergic inflammation and brain cancer.
  • Vincent Hascall, Ph.D., Biomedical Engineering, structure, function and metabolism of Proteoglycans and Hyaluronan in connective tissues.
  • Cliff Harding, M.D., Ph.D., CWRU, Pathology, antigen presentation and processing, Toll-like receptors.
  • Stanley Hazen, M.D., Ph.D., Cell Biology, leukocyte peroxidases; nitric oxide, reactive oxygen species, inflammation, atherosclerosis.
  • Warren Heston, Ph.D., Cancer Biology, prostate cancer development and targeting of prostate-specific membrane antigen for therapy.
  • Joe Hollyfield, Ph.D., Ophthalmic Research, study of the structure, development, and function of the eye and visual system in health and disease.
  • Jane Hoover-Plow, Ph.D., Cardiovascular Medicine, plasminogen dependent cell migration in inflammation, genetic determinants of thrombosis.
  • Janet Houghton, Ph.D., Cancer Biology, developmental therapeutics, death receptor signaling and therapeutic response.
  • Philip Howe, Ph.D., Cancer Biology, molecular mechanism of Transforming Growth Factor Beta (TGFbeta) growth action.
  • Bo Hu, Ph.D., Quantitative Health Sciences, model selection, longitudinal analysis, adaptive design, Bayesian modeling and computing.
  • Peter Imrey, Ph.D., Quantitative Health Sciences, categorical data analysis, statistical methods in observational epidemiology, and sample survey methods.
  • Hemant Ishwaran, Ph.D., Quantitative Health Sciences, data mining, ensembles, and high dimensional variable selection and prediction.
  • Donald Jacobsen, Ph.D., Cell Biology, homocysteine, vitamin metabolism, vascular disease.
  • Damir Janigro, Ph.D., Neurological Surgery, blood brain barrier, multiple drug resistance, molecular/proteomic analysis of neurological disorders.
  • Jan Jensen, Ph.D., Stem Cell Biology & Regenerative Medicine, developmental biology of the pancreas with a focus on the molecular mechanisms controlling insulin-cell development.
  • Trine Jorgensen, Ph.D., Immunology, molecular mechanisms of gender differences in lupus-like disease.
  • Jonathan Karn, Ph.D., CWRU, Molecular Biology and Microbiology.
  • Sadashiva Karnik, Ph.D., Molecular Cardiology, molecular and cellular mechanisms of angiotensin receptor II function and signal transduction.
  • Michael Kattan, Ph.D., Quantitative Health Sciences, development, validation, and use of prediction models. 
  • David Katz, Ph.D., CWRU, Neurosciences, define regulatory interactions in the developing nervous system and to understand how perturbations of development result in disease.
  • John Kirwan, Ph.D., Pathobiology, systems integrated physiology.
  • Hitoshi Komuro, Ph.D., Neurosciences, neuronal cytoarchitecture and synapse function.
  • Qinzhong Kong, Ph.D., CWRU, Pathology, assessing the transmissibility of CWD to humans.
  • Gary Koski, Ph.D., Immunology, human dendritic cell biology as it relates to innate immunity and cancer immunotherapy.
  • Diane Kunze, Ph.D., Metro, Research & Neuroscience, ion channels in the neural regulation of cardiovascular and respiratory function.
  • Andrea Ladd, Ph.D., Cell Biology, regulation of RNA splicing, cardiac development.
  • Vinod Labhasetwar, Ph.D., Biomedical Engineering, nuclear-targeted nano-particles for gene delivery.
  • Bruce Lamb, Ph.D., Neurosciences, molecular basis of Alzheimer's disease using transgenic mouse models.
  • Veronique Lefebvre, Ph.D., Cell Biology, transcription factor control of cell fate and differentiation.
  • Liang Li, Ph.D., Quantitative Health Sciences, longitudinal and survival analysis, measurement error models, and genetic epidemiology.
  • Xiaoxia Li, Ph.D., Immunology, signal transduction in innate and adaptive immunity.
  • Daniel Lindner, M.D., Ph.D., Taussig Cancer Center, regulation of apoptosis by nitrosylcobalamin and interferon in malignancies.
  • Lina Lu, M.D., Immunology, prevention of hemophilia A inhibitors by administration of tolerogenic dendritic cells.
  • Donal Luse, Ph.D., Molecular Genetics, mechanism of transcript initiation and elongation by RNA polymerase II.
  • Jaroslaw Maciejewski, M.D., Ph.D., Taussig Cancer Center, bone marrow failure syndromes.
  • Wendy Macklin, Ph.D., Neurosciences, molecular control of oligodendrocyte differentiation during brain development.
  • Sanford Markowitz, M.D., Ph.D., Medicine/Cancer Genetics, genetic mutations in human gastrointestinal cancers.
  • Edward Mascha, Ph.D., Quantitative Health Sciences, clinical trials, causal effects, reliability studies, longitudinal data analyses, and correlated data problems.
  • Edward Maytin, M.D., Ph.D., Dermatology/Biomedical Engineering, dermatology research.
  • Todor Mazgalev, Ph.D., Molecular Cardiology, novel therapeutic approaches for treatment of atrial fibrillation.
  • Cahir McDevitt, Ph.D., Biomedical Engineering, cell-matrix interactions in the repair of connective tissues.
  • Christine McDonald, Pathobiology, Nod2 signaling in inflammatory bowel disease.
  • Cameron McIntyre, Ph.D., Biomedical Engineering, development of deep brain stimulation for treatment of neurological disorders.
  • Thomas McIntyre, Ph.D., Cell Biology, inflammation, signaling and lipid mediators.
  • Ronald Midura, Ph.D., Biomedical Engineering, regulation of primary bone formation, connective tissue biology.
  • Booki Min, Ph.D., Immunology, T cell homeostasis, memory T cells.
  • Saurav Misra, Ph.D., Molecular Cardiology, structural biology of ubiquitin signaling and intracellular trafficking.
  • Rocio Moran, M.D., Genomic Medicine Institute, inborn errors of metabolism and cardiovascular genetics.
  • Richard Morton, Ph.D., Cell Biology, lipid and lipoprotein metabolism.
  • Paul Murray, Ph.D., Anesthesiology Research, neural, humoral and local mechanisms that are involved in the fundamental regulation of the normal pulmonary circulation.
  • Laura Nagy, Ph.D., Pathobiology, regulation of G-protein mediated signal transduction ethanol.
  • Marvin Natowicz, M.D., Ph.D., Genomic Medicine Institute, clinical chemistry of inherited metabolic disorders.
  • Nancy Obuchowski, Ph.D., Quantitative Health Sciences, design and analysis of studies of screening and diagnostic tests.
  • Richard Padgett, Ph.D., Molecular Genetics, mechanisms of RNA splicing in vivo and in vitro.
  • Neal Peachey, Ph.D., Ophthalmic Research, hereditary retinal disease.
  • Dianne Perez, Ph.D., Molecular Cardiology, structure-function and physiological studies of adrenergic receptors.
  • Sanjay Pimplikar, Ph.D., Neurosciences, cell biology of alzheimer’s disease.
  • Gregory Plautz, M.D., Pediatric Hematology & Oncology, dendritic cell-brain tumor stem cell fusion vaccines.
  • Ed Plow, Ph.D., Molecular Cardiology, cell adhesion and migration, integrins, platelets, plasminogen.
  • Eugene Podrez, Ph.D., Molecular Cardiology, cholesterol and lipid uptake and signaling in atherosclerosis.
  • Sathyamangla Prasad, Ph.D., Molecular Cardiology, regulation of G-protein coupled receptor (GPCR) signaling.
  • Shiguang Qian, Ph.D., Immunology, mechanistic insights into liver transplant tolerance, effect of antagonism of chemokines on allograft rejection.
  • Jun Qin, Ph.D., Molecular Cardiology, structural biology and biochemistry of integrin signal transduction.
  • Richard Ransohoff, M.D., Neurosciences, multiple sclerosis and chemokine expression in central nervous system inflammation.
  • Ofer Reizes, Ph.D., Cell Biology, obesity, adipose tissue development and maintenance.
  • Kurt Runge, Ph.D., Molecular Genetics, yeast telomeres: length regulation and roles in chromosome stability.
  • Takao Sakai, M.D., Ph.D., Biomedical Engineering, cell biology of integrins and fibronectin in wound healing and disease.
  • Ephraim Sehayek, M.D., Genomic Medicine Institute, defining the relationship of sterol and fat absorption to reverse cholesterol transport and atherosclerosis cardiovascular diseases.
  • Ganes Sen, Ph.D., Molecular Genetics, host responses to virus infection.
  • Subha Sen, Ph.D., D.Sc., Molecular Cardiology, development and regression of myocardial hypertrophy.
  • David Serre, Ph.D., Genomic Medicine Institute, genetic basis of Type 2 Diabetes and obesity and their origins.
  • Robert Silverman, Ph.D., Cancer Biology, innate defense against viruses and cancer.
  • Roy Silverstein, M.D., Cell Biology, CD36 signaling and atherosclerosis.
  • Neena Singh, M.D., Ph.D., CWRU, Pathology, the pathophysiology underlying human Prion disorders.
  • Nywana Sizemore, Ph.D., Cancer Biology, signal transduction, gene expression, oncogenesis, and apoptosis in colorectal and other cancers.
  • Jonathan Smith, Ph.D., Cell Biology, lipoprotein metabolism, cholesterol trafficking, genetics of atherosclerosis.
  • William Smith, D.Eng., Biomedical Engineering, engineering pumps and devices for cardiac assist treatment, engineering of artificial hearts.
  • Dennis Stacey, Ph.D., Molecular Genetics, proliferative signal transduction and cell cycle regulation by oncogenes and anti-tumor drugs.
  • George Stark, Ph.D., Molecular Genetics, signal transduction pathways involving interferons, STATs, NFKB, p53 and TGF ß, methods for forward genetics in mammalian cells.
  • Susan Staugaitis, M.D., Ph.D., Neurosciences, properties of glial cells and glial brain tumors.
  • Olga Stenina, Ph.D., Molecular Cardiology, regulation of vascular gene expression by glucose, functions of thrombospondin-4.
  • Stephen Stohlman, Ph.D., Neurosciences, interactions of the immune system and CNS in models of MS.
  • Dennis Stuehr, Ph.D., Pathobiology, structure and biochemistry of nitric oxide synthases.
  • Hisashi Tanaka, M.D., Ph.D., Molecular Genetics, genetic and genomic factors regulating the evolution of cancer genomes.
  • Curtis Tatsuoka, Ph.D., Quantitative Health Sciences, statistical models of cognition, sequential experimental design, and quality of life measurement.
  • Angela Ting, Ph.D., Genomic Medicine Institute, epigenetic gene regulation involves DNA methylation and histone modifications.
  • Bruce Trapp, Ph.D., Neurosciences, cellular and molecular biology of myelination, demyelination, and dysmyelination.
  • Pierre Triozzi, M.D., Taussig Cancer Center, medical oncology, melanoma, hematology, experimental therapeutics, and cancer vaccines.
  • Vince Tuohy, Ph.D., Immunology, immunoregulation of autoimmunity, T-cell biology and gene therapy for autoimmunity.
  • Anna Valujskikh, Ph.D., Immunology, CD4 memory T cells and allograft rejection.
  • Antonie van den Bogert, Ph.D., Biomedical Engineering, biomechanics and neuromuscular control of human movement.
  • David Van Wagoner, Ph.D., Molecular Cardiology, myocyte biology, electrophysiology, and arrhythmias.
  • Jerrold Vitek, M.D., Ph.D., Neurosciences, Deep Brain Stimulation (DBS), the pathophysiology of movement disorders, and exploring new applications for DBS
  • Qing Wang, Ph.D., Molecular Cardiology, human genetics of heart attacks and arrhythmias.
  • Xiaofeng Wang, Ph.D., Quantitative Health Sciences, neuroinformatics, biomedical signal analysis, and statistical image analysis.
  • Steven Wilson, M.D., Ophthalmic Research, refractive surgery -- LASIK and PRK.
  • Qingyu Wu, M.D., Ph.D., Molecular Cardiology, serine proteases of the trypsin superfamily.
  • Riqiang Yan, Ph.D., Neurosciences, molecular and functional study of Alzheimer's beta-secretase and its modulators in Alzheimer's disease.
  • Taolin Yi, Ph.D., Cancer Biology, pathogenic role of and novel therapeutics targeting protein tyrosine phosphatases in malignant diseases.
  • Guang Yue, Ph.D., Biomedical Engineering, neural control of voluntary movement and muscle contraction, motor-function recovery after injury and stroke.
  • Maceij Zborowski, Ph.D., Biomedical Engineering, development of separation technologies for medical applications.
  • Bin Zhang, Ph.D., Genomic Medicine Institute, mechanisms of protein transport from the endoplasmic reticulum (ER) to the Golgi body.
  • Li Zhang, Ph.D., Quantitative Health Sciences, case-control studies, genetic epidemiology, statistical genetics, and Bayesian statistics.
  • Lan Zhou, M.D., Ph.D., Neurology, role of TGF-B1 in duchenne muscular dystrophy.
  • Alan Zhu, Ph.D., Cell Biology, hedgehog signaling, vesicle trafficking, cytoskeletal dynamics.