Molecular Medicine Faculty
- Derek Abbott, M.D., Ph.D., CWRU, Pathology, signaling pathways responsible for NOD2-induced Crohn's Disease.
- Jay Alberts, Ph.D., Biomedical Engineering, neural aspects of movement control and upper extremity function.
- Micheala Aldred, Ph.D., Genomic Medicine Institute, chromosome deletions in development and cancer.
- Alex Almasan, Ph.D., Cancer Biology, DNA damage responses, radiation-regulated genes, cell cycle control, and apoptosis.
- Bela Anand-Apte, M.D., Ph.D., Ophthalmic Research, diabetic retinopathy and age-related macular degeneration.
- Suneel Apte, M.B.B.S., D.Phil., Biomedical Engineering, extracellular matrix remodeling by metalloproteinases.
- Mark Aronica, M.D., Medicine, synthesis and turnover of extracellular matrix in asthma.
- Amiya Banerjee, Ph.D., Virology, gene expression of negative-strand RNA viruses.
- John Barnard, Ph.D., Quantitative Health Sciences, statistical genetics, missing data problems, Bayesian statistics, bioinformatics and statistical computing.
- Gerald Beck, Ph.D., Quantitative Health Sciences, data coordination for clinical trials (hemodialysis and dialysis access consortium).
- Cornelia Bergmann, Ph.D., Neurosciences, regulation of and function of CD8 T cells during viral infections of the central nervous system (CNS) associated with demyelination.
- Kathleen Berkner, Ph.D., Molecular Cardiology, carboxylation of vitamin K- dependent proteins.
- Henry Boom, M.D., CWRU, Medicine, heterogeneity of T-cells in M. tuberculosis infection.
- Ernest Borden, M.D., Cancer Biology, melanoma cancer therapies, interferons, vaccines, and antibodies.
- Matthias Buck, Ph.D., CWRU, Physiology and Biophysics, molecular biophysics of small GTPase-protein interactions in neuronal cell signaling.
- Tatiana Byzova, Ph.D., Molecular Cardiology, cell adhesion molecules/integrins in thrombosis, vascular biology and cancer.
- Martha Cathcart, Ph.D., Cell Biology, monocyte signal transduction, activation, chronic inflammation.
- Shu Chen, Ph.D., CWRU, Pathology, LRRK2: pathway to parkinson disease.
- Xi Chen, Ph.D., Quantitative Health Sciences, high-throughput genomic data analysis, pharmacogenomics, genetic epidemiology and correlated data analysis.
- Jianguo Cheng, M.D., Ph.D., Anesthesiology Research,
interventional pain management and spinal cord stimulation.
- Yuanna Cheng, M.D., Ph.D., Molecular Cardiology, cardiac arrhythmogenesis and remodeling following left ventricular reconstruction.
- Guy Chisolm, Ph.D., Cell Biology, cellular effects of lipoprotein oxidation products on inflammation and atherosclerosis.
- Peter Chumakov, M.D., Ph.D., Molecular Genetics, p53-dependent mechanisms of proliferation control and maintenance of genetic stability.
- Peter Cohen, M.D., Surgery Research, immunotherapy
- Clemencia Colmenares, Ph.D., Cancer Biology, role of c-ski proto-oncogene in growth and development.
- John Crabb, Ph.D., Ophthalmic Research,
biochemistry of vision in proteome changes associated with retinal degenerative diseases and the mammalian visual cycle.
- Margot Damaser, Ph.D., Biomedical Engineering, soft-tissue biomechanics, incontinence and nerve regeneration.
- Brian Davis, Ph.D., Biomedical Engineering, biomechanics of the lower extremities.
- Carol de la Motte, Ph.D., Pathobiology,
role of extracellular matrix to inflammatory cell recruitment and activation involved in diseases of the intestine and lung.
- Kathleen Derwin, Ph.D., Biomedical Engineering, tendon mechanobiology and tissue engineering.
- Paul DiCorleto, Ph.D., Cell Biology, Chair of Molecular Medicine, growth factors and atherosclerosis.
- Donna Driscoll, Ph.D., Cell Biology, posttranscriptional regulation of gene expression, RNA structure and function.
- Thomas Egelhoff, Ph.D., Cell Biology, mechanisms regulating cytoskeletal function during cell migration and cytokinesis.
- Paul Elson, Sc.D., Quantitative Health Sciences, group-sequential methods and clinical trials.
- Charis Eng, M.D., Ph.D., Genomic Medicine Institute, human cancer genomics, personalized medicine.
- Serpil Erzurum, M.D., Pathobiology, airway inflammation, reactive oxygen and nitrogen species.
- Rob Fairchild, Ph.D., Immunology, skin and cardiac allograft rejection, peripheral T lymphocyte recruitment.
- Maria Febbraio, Ph.D., Cell Biology, scavenger receptors and atherosclerosis, fatty acid transport and metabolism.
- Ariel Feldstein, M.D., Cell Biology, nonalcoholic fatty liver disease.
- Jim Finke, Ph.D., Immunology, tumor immunity, T lymphocytes, signal transduction.
- Claudio Fiocchi, M.D., Pathobiology, pathogenesis of inflammatory bowel disease and animal models of IBD.
- Elizabeth Fisher, Ph.D., Biomedical Engineering, image analysis for monitoring of multiple sclerosis.
- Aaron Fleischman, Ph.D., Biomedical Engineering, development of microelectromechanical systems (MEMS) technology for biomedical applications.
- Joan Fox, Ph.D., Molecular Cardiology, molecular mechanisms by which stress induces cardiovascular disease.
- Paul Fox, Ph.D., Cell Biology, RNA structure and regulation of translation.
- Alex Zhenghong Fu, Ph.D., Quantitative Health Sciences, health economics, pharmacoeconomics, health outcome and health service research.
- Kiyotaka Fukamachi, M.D., Ph.D., Biomedical Engineering, development of surgical devices for heart failure treatment.
- Ram Ganapathi, Ph.D., Taussig Cancer Center, clinical pharmacology and experimental cancer chemotherapy.
- Leonard Golding, M.D., Biomedical Engineering, devices for cardiac support and stabilization in heart failure.
- Linda Graham, M.D., Biomedical Engineering, healing of prosthetic vascular grafts.
- Neetu Gupta, Ph.D., Immunology, plasma membrane and actin cytoskeletal dynamics during B cell activation.
- Stephanie Hagstrom, Ph.D., Ophthalmic Research, macular degeneration, retiniti's pigmentosa, and genetics of inherited retinal degeneration.
- Thomas Hamilton, Ph.D., Immunology, inflammatory gene expression in mononuclear phagocytes.
- Jaharul Haque, Ph.D., Cancer Biology, cytokine-mediated cell signaling in allergic inflammation and brain cancer.
- Vincent Hascall, Ph.D., Biomedical Engineering, structure, function and metabolism of Proteoglycans and Hyaluronan in connective tissues.
- Cliff Harding, M.D., Ph.D., CWRU, Pathology, antigen presentation and processing, Toll-like receptors.
- Stanley Hazen, M.D., Ph.D., Cell Biology, leukocyte peroxidases; nitric oxide, reactive oxygen species, inflammation, atherosclerosis.
- Warren Heston, Ph.D., Cancer Biology, prostate cancer development and targeting of prostate-specific membrane antigen for therapy.
- Joe Hollyfield, Ph.D., Ophthalmic Research, study of the structure, development, and function of the eye and visual system in health and disease.
- Jane Hoover-Plow, Ph.D., Cardiovascular Medicine, plasminogen dependent cell migration in inflammation, genetic determinants of thrombosis.
- Janet Houghton, Ph.D., Cancer Biology, developmental therapeutics, death receptor signaling and therapeutic response.
- Philip Howe, Ph.D., Cancer Biology, molecular mechanism of Transforming Growth Factor Beta (TGFbeta) growth action.
- Bo Hu, Ph.D., Quantitative Health Sciences,
model selection, longitudinal analysis, adaptive design, Bayesian modeling and computing.
- Peter Imrey, Ph.D., Quantitative Health Sciences, categorical data analysis, statistical methods in observational epidemiology, and sample survey methods.
- Hemant Ishwaran, Ph.D., Quantitative Health Sciences, data mining, ensembles, and high dimensional variable selection and prediction.
- Donald Jacobsen, Ph.D., Cell Biology, homocysteine, vitamin metabolism, vascular disease.
- Damir Janigro, Ph.D., Neurological Surgery, blood brain barrier, multiple drug resistance, molecular/proteomic analysis of neurological disorders.
- Jan Jensen, Ph.D., Stem Cell Biology & Regenerative Medicine, developmental biology of the pancreas with a focus on the molecular mechanisms controlling insulin-cell development.
- Trine Jorgensen, Ph.D., Immunology, molecular mechanisms of gender differences in lupus-like disease.
- Jonathan Karn, Ph.D., CWRU, Molecular Biology and Microbiology.
- Sadashiva Karnik, Ph.D., Molecular Cardiology, molecular and cellular mechanisms of angiotensin receptor II function and signal transduction.
- Michael Kattan, Ph.D., Quantitative Health Sciences, development, validation, and use of prediction models.
- David Katz, Ph.D., CWRU, Neurosciences, define regulatory interactions in the developing nervous system and to understand how perturbations of development result in disease.
- John Kirwan, Ph.D., Pathobiology, systems integrated physiology.
- Hitoshi Komuro, Ph.D., Neurosciences, neuronal cytoarchitecture and synapse function.
- Qinzhong Kong, Ph.D., CWRU, Pathology, assessing the transmissibility of CWD to humans.
- Gary Koski, Ph.D., Immunology, human dendritic cell biology as it relates to innate immunity and cancer immunotherapy.
- Diane Kunze, Ph.D., Metro, Research & Neuroscience, ion channels in the neural regulation of cardiovascular and respiratory function.
- Andrea Ladd, Ph.D., Cell Biology, regulation of RNA splicing, cardiac development.
- Vinod Labhasetwar, Ph.D., Biomedical Engineering, nuclear-targeted nano-particles for gene delivery.
- Bruce Lamb, Ph.D., Neurosciences, molecular basis of Alzheimer's disease using transgenic mouse models.
- Veronique Lefebvre, Ph.D., Cell Biology, transcription factor control of cell fate and differentiation.
- Liang Li, Ph.D., Quantitative Health Sciences, longitudinal and survival analysis, measurement error models, and genetic epidemiology.
- Xiaoxia Li, Ph.D., Immunology, signal transduction in innate and adaptive immunity.
- Daniel Lindner, M.D., Ph.D., Taussig Cancer Center, regulation of apoptosis by nitrosylcobalamin and interferon in malignancies.
- Lina Lu, M.D., Immunology, prevention of hemophilia A inhibitors by administration of tolerogenic dendritic cells.
- Donal Luse, Ph.D., Molecular Genetics, mechanism of transcript initiation and elongation by RNA polymerase II.
- Jaroslaw Maciejewski, M.D., Ph.D., Taussig Cancer Center, bone marrow failure syndromes.
- Wendy Macklin, Ph.D., Neurosciences, molecular control of oligodendrocyte differentiation during brain development.
- Sanford Markowitz, M.D., Ph.D., Medicine/Cancer Genetics, genetic mutations in human gastrointestinal cancers.
- Edward Mascha, Ph.D., Quantitative Health Sciences,
clinical trials, causal effects, reliability studies, longitudinal data analyses, and correlated data problems.
- Edward Maytin, M.D., Ph.D., Dermatology/Biomedical Engineering, dermatology research.
- Todor Mazgalev, Ph.D., Molecular Cardiology, novel therapeutic approaches for treatment of atrial fibrillation.
- Cahir McDevitt, Ph.D., Biomedical Engineering, cell-matrix interactions in the repair of connective tissues.
- Christine McDonald, Pathobiology, Nod2 signaling in inflammatory bowel disease.
- Cameron McIntyre, Ph.D., Biomedical Engineering, development of deep brain stimulation for treatment of neurological disorders.
- Thomas McIntyre, Ph.D., Cell Biology, inflammation, signaling and lipid mediators.
- Ronald Midura, Ph.D., Biomedical Engineering, regulation of primary bone formation, connective tissue biology.
- Booki Min, Ph.D., Immunology, T cell homeostasis, memory T cells.
- Saurav Misra, Ph.D., Molecular Cardiology, structural biology of ubiquitin signaling and intracellular trafficking.
- Rocio Moran, M.D., Genomic Medicine Institute, inborn errors of metabolism and cardiovascular genetics.
- Richard Morton, Ph.D., Cell Biology, lipid and lipoprotein metabolism.
- Paul Murray, Ph.D., Anesthesiology Research, neural, humoral and local mechanisms that are involved in the fundamental regulation of the normal pulmonary circulation.
- Laura Nagy, Ph.D., Pathobiology, regulation of G-protein mediated signal transduction ethanol.
- Marvin Natowicz, M.D., Ph.D., Genomic Medicine Institute, clinical chemistry of inherited metabolic disorders.
- Nancy Obuchowski, Ph.D., Quantitative Health Sciences,
design and analysis of studies of screening and diagnostic tests.
- Richard Padgett, Ph.D., Molecular Genetics, mechanisms of RNA splicing in vivo and in vitro.
- Neal Peachey, Ph.D., Ophthalmic Research, hereditary retinal disease.
- Dianne Perez, Ph.D., Molecular Cardiology, structure-function and physiological studies of adrenergic receptors.
- Sanjay Pimplikar, Ph.D., Neurosciences, cell biology of alzheimer’s disease.
- Gregory Plautz, M.D., Pediatric Hematology & Oncology, dendritic cell-brain tumor stem cell fusion vaccines.
- Ed Plow, Ph.D., Molecular Cardiology, cell adhesion and migration, integrins, platelets, plasminogen.
- Eugene Podrez, Ph.D., Molecular Cardiology, cholesterol and lipid uptake and signaling in atherosclerosis.
- Sathyamangla Prasad, Ph.D., Molecular Cardiology, regulation of G-protein coupled receptor (GPCR) signaling.
- Shiguang Qian, Ph.D., Immunology, mechanistic insights into liver transplant tolerance, effect of antagonism of chemokines on allograft rejection.
- Jun Qin, Ph.D., Molecular Cardiology, structural biology and biochemistry of integrin signal transduction.
- Richard Ransohoff, M.D., Neurosciences, multiple sclerosis and chemokine expression in central nervous system inflammation.
- Ofer Reizes, Ph.D., Cell Biology, obesity, adipose tissue development and maintenance.
- Kurt Runge, Ph.D., Molecular Genetics, yeast telomeres: length regulation and roles in chromosome stability.
- Takao Sakai, M.D., Ph.D., Biomedical Engineering, cell biology of integrins and fibronectin in wound healing and disease.
- Ephraim Sehayek, M.D., Genomic Medicine Institute, defining the relationship of sterol and fat absorption to reverse cholesterol transport and atherosclerosis cardiovascular diseases.
- Ganes Sen, Ph.D., Molecular Genetics, host responses to virus infection.
- Subha Sen, Ph.D., D.Sc., Molecular Cardiology, development and regression of myocardial hypertrophy.
- David Serre, Ph.D., Genomic Medicine Institute, genetic basis of Type 2 Diabetes and obesity and their origins.
- Robert Silverman, Ph.D., Cancer Biology, innate defense against viruses and cancer.
- Roy Silverstein, M.D., Cell Biology, CD36 signaling and atherosclerosis.
- Neena Singh, M.D., Ph.D., CWRU, Pathology, the pathophysiology underlying human Prion disorders.
- Nywana Sizemore, Ph.D., Cancer Biology, signal transduction, gene expression, oncogenesis, and apoptosis in colorectal and other cancers.
- Jonathan Smith, Ph.D., Cell Biology, lipoprotein metabolism, cholesterol trafficking, genetics of atherosclerosis.
- William Smith, D.Eng., Biomedical Engineering, engineering pumps and devices for cardiac assist treatment, engineering of artificial hearts.
- Dennis Stacey, Ph.D., Molecular Genetics, proliferative signal transduction and cell cycle regulation by oncogenes and anti-tumor drugs.
- George Stark, Ph.D., Molecular Genetics, signal transduction pathways involving interferons, STATs, NFKB, p53 and TGF ß, methods for forward genetics in mammalian cells.
- Susan Staugaitis, M.D., Ph.D., Neurosciences, properties of glial cells and glial brain tumors.
- Olga Stenina, Ph.D., Molecular Cardiology, regulation of vascular gene expression by glucose, functions of thrombospondin-4.
- Stephen Stohlman, Ph.D., Neurosciences, interactions of the immune system and CNS in models of MS.
- Dennis Stuehr, Ph.D., Pathobiology, structure and biochemistry of nitric oxide synthases.
- Hisashi Tanaka, M.D., Ph.D., Molecular Genetics, genetic and genomic factors regulating the evolution of cancer genomes.
- Curtis Tatsuoka, Ph.D., Quantitative Health Sciences,
statistical models of cognition, sequential experimental design, and quality of life measurement.
- Angela Ting, Ph.D., Genomic Medicine Institute, epigenetic gene regulation involves DNA methylation and histone modifications.
- Bruce Trapp, Ph.D., Neurosciences, cellular and molecular biology of myelination, demyelination, and dysmyelination.
- Pierre Triozzi, M.D., Taussig Cancer Center, medical oncology, melanoma, hematology, experimental therapeutics, and cancer vaccines.
- Vince Tuohy, Ph.D., Immunology, immunoregulation of autoimmunity, T-cell biology and gene therapy for autoimmunity.
- Anna Valujskikh, Ph.D., Immunology, CD4 memory T cells and allograft rejection.
- Antonie van den Bogert, Ph.D., Biomedical Engineering, biomechanics and neuromuscular control of human movement.
- David Van Wagoner, Ph.D., Molecular Cardiology, myocyte biology, electrophysiology, and arrhythmias.
- Jerrold Vitek, M.D., Ph.D., Neurosciences, Deep Brain Stimulation (DBS), the pathophysiology of movement disorders, and exploring new applications for DBS
- Qing Wang, Ph.D., Molecular Cardiology, human genetics of heart attacks and arrhythmias.
- Xiaofeng Wang, Ph.D., Quantitative Health Sciences, neuroinformatics, biomedical signal analysis, and statistical image analysis.
- Steven Wilson, M.D., Ophthalmic Research, refractive surgery -- LASIK and PRK.
- Qingyu Wu, M.D., Ph.D., Molecular Cardiology, serine proteases of the trypsin superfamily.
- Riqiang Yan, Ph.D., Neurosciences, molecular and functional study of Alzheimer's beta-secretase and its modulators in Alzheimer's disease.
- Taolin Yi, Ph.D., Cancer Biology, pathogenic role of and novel therapeutics targeting protein tyrosine phosphatases in malignant diseases.
- Guang Yue, Ph.D., Biomedical Engineering, neural control of voluntary movement and muscle contraction, motor-function recovery after injury and stroke.
- Maceij Zborowski, Ph.D., Biomedical Engineering, development of separation technologies for medical applications.
- Bin Zhang, Ph.D., Genomic Medicine Institute, mechanisms of protein transport from the endoplasmic reticulum (ER) to the Golgi body.
- Li Zhang, Ph.D., Quantitative Health Sciences,
case-control studies, genetic epidemiology, statistical genetics, and Bayesian statistics.
- Lan Zhou, M.D., Ph.D., Neurology, role of TGF-B1 in duchenne muscular dystrophy.
- Alan Zhu, Ph.D., Cell Biology, hedgehog signaling, vesicle trafficking, cytoskeletal dynamics.
