Publications

Guryanova OA, Drazba JA, Frolova EI and Chumakov PM (2011) Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL. J. Biol. Chem. (EPub).

Zheltukhin AO and Chumakov PM (2010) Constitutive and induced functions of the p53 gene. Biochemistry, 75:1692-1721.

Khutornenko AA, Roudko VV, Chernyak BV, Vartapetian AB, Chumakov PM, Evstafieva AG (2010) Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway. Proc. Natl. Acad. Sci. USA, 107:12828-12833. PMCID: PMC2919937.

Chumakov SP, Kravchenko JE, Prassolov VS, Frolova EI, Chumakov PM (2010) Efficient downregulation of multiple mRNA targets with a single shRNA-expressing lentiviral vector. Plasmid, 63:143-149. PMCID: PMC2849729.

Olovnikov IA, Kravchenko JE and Chumakov PM. (2009) Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense. Semin. Cancer Biol. 19:32-41. PMCID: PMC2646792.

Chumakov SP, Ilyinskaya GV, Kravchenko JE, Frolova EI, Prassolov VS and Chumakov PM (2008) A lentivirus based system for quantitative detection of intracellular translocations of recombinant proteins. Mol. Biol. 42:1004-1011. PMCID: PMC2745109.

Kravchenko JE, Ilyinskaya GV, Komarov PG, Agapova LS, Kochetkov DV, Strom E, Frolova EI, Kovriga I, Gudkov AV, Feinstein E, Chumakov PM (2008) Small molecule RETRA suppresses mutant p53-bearing cancer cells through a p73 dependent salvage pathway. Proc. Natl. Acad. Sci. USA, 105: 6302-6307. PMCID: PMC2327210.

Chumakov PM. (2007) Versatile functions of p53 protein in multicellular organisms. Biochemistry 72:1399-1421. PMCID: PMC2709848.

Kopnin PB, Agapova LS, Kopnin BP and Chumakov PM. (2007) Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability. Cancer Res. 67:4671-4678. PMCID: PMC2657553.

Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE and Chumakov PM. (2005) The antioxidant function of the p53 tumor suppressor. Nat. Med. 11:1306-1313.

Rokhlin OW, Taghiyev AF, Guseva NV, Glover RA, Chumakov PM, Kravchenko JE and Cohen MB. (2005) Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP. Oncogene 24:6773-6784.

Kravchenko JE, Rogozin IB, Koonin EV and Chumakov PM. (2005) Transcription of mammalian mRNAs by a novel nuclear RNA polymerase of mitochondrial origin. Nature 436:735-739.

Razorenova OV, Ivanov AV, Budanov AV and Chumakov PM. (2005) Virus-based reporter systems for monitoring transcriptional activity of hypoxia-inducible factor 1. Gene 350:89-98.

Agapova LS, Volodina JL, Chumakov PM and Kopnin BP. (2004) Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint. J. Biol. Chem. 279:36382-36389.

Budanov AV, Sablina AA, Feinstein E, Koonin EV and Chumakov PM. (2004) Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 304:596-600.

Gurova KV, Hill JE, Razorenova OV, Chumakov PM and Gudkov AV. (2004) p53 pathway in renal cell carcinoma is repressed by a dominant mechanism. Cancer Res. 64:1951-1958.

Logunov DY, Ilyinskaya GV, Verhovskaya LV, Cherenova LV, Shmarov MM, Doronin KK, Chumakov PM et al. (2004) Restoration of p53 tumor-suppressor activity in human tumor cells in vitro and their xenografts in vivo by recombinant avian adenovirus CELO-p53. Gene Therapy 11:79-84.

Sablina AA, Kopnin BP and Chumakov PM. (2003) Tumor Suppressor p53 and its Homologue p73alpha Affect Cell Migration. J. Biol. Chem. 278:27362-27371.

Gurova KV, Rokhlin OW, Budanov AV, Burdelya LG, Chumakov PM, Cohen MB and Gudkov AV. (2003) Cooperation of two mutant p53 alleles contributes to Fas resistance of prostate carcinoma cells. Cancer Res. 63:2905-2912.