Donal S. Luse, Ph.D. Staff Department of Molecular Genetics Lerner Research Institute / NE20 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 445-7688 Fax: (216) 444-0512 Email: lused@ccf.org

Area of general research interest:

Mechanism of transcript initiation and elongation by RNA polymerase II

Current program:

• Initiation mechanisms and promoter clearance by RNA polymerase II
• Molecular mechanisms of transcript elongation by RNA polymerase II
• The role of chromatin structure in transcript initiation and elongation

Investigators:

• Susan W. Luse, B.S., Technical Associate
• Melissa Mullen, Ph.D., Postdoctoral Fellow

Collaborators:

• Dr. Vasily Studitsky, Univ. of Medicine and Dentistry of New Jersey
• Dr. David Price, Univ. of Iowa