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Wendy B. Macklin, Ph.D.Staff
Department of Neurosciences
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Area of general research interest:
Molecular control of oligodendrocyte differentiation during brain development.
Current program:
- Studies on the regulatory elements of the myelin proteolipid protein gene.
- Studies on animals carrying mutations in the myelin proteolipid protein gene.
- Studies using a PLP-Lac2 transgene to track oligodendrocyte differentiation on normal and mutant animals.
- Studies on a GTPase activity protein in oligodendrocytes and neurons.
Investigators:
- Ana Flores, Ph.D.
- Yuko Fujita, Ph.D.
- Tatyana Gudz, Ph.D.
- Cindy Kangas
- Elizabeth Schick, B.S.
Collaborators:
- Dr. Robert Miller, Dept. of Neurosciences, Case Western Reserve University, Cleveland, OH
- Dr. Phillip Kahle, Dept. of Biochemistry, Ludwig Maximilians University, Munich, Germany
- Dr. Steve Stohlman, Dept. of Neurology, Keck SOM, University of Southern California, Los Angeles, CA