Riqiang Yan, Ph.D. Associate Staff Department of Neurosciences Lerner Research Institute / NC30 9500 Euclid Avenue Cleveland, Ohio 44195 Telephone: (216) 445-2690 Fax: (216) 444-7927 yanr@ccf.org

Area of general research interest:

Molecular and Cellular Biological Research in Alzheimer's Disease

Current program:

• Functional study of Alzheimer's beta-secretase (BACE1).
• Characterizations of BACE1 modulators including Reticulon/Nogo proteins.

Investigators:

• Wanxia He, BS
• Xiangyou Hu, MD, Ph.D.
• Marguerite Prior, Ph.D
• Qi Shi, MD, Ph.D.
• Xiaoying Tang, MS
• Xiangdong Zhou, Ph.D.

Collaborators:

• Allan Levey (Emory University School of Medicine)
• Paul Aisen (Georgetown University, Washington, D.C.)
• Wendy Macklin  (Dept. of Neurosciences, CCF)
• Yasuji Matsuoka (Georgetown University, Washington, D.C.)
• Akihiko Takashima (Riken Institute, Tokyo, Japan)
• Bruce Trapp (Dept. of Neurosciences, CCF)
• Hitoshi Komuro (Dept. of Neurosciences, CCF)