In the Media

Hits for a cause

Adam Bartsch, PhD, records some of the first data on a study using the Intelligent Mouth Guard in hockey players to capture speed and impact data related to concussive hits. The study is part of a collaboration with Edward Benzel, MD, Neurological Surgeon, and Jay Alberts, PhD, Biomedical Engineer, aiming to, for the first time, record accurate head-impact data to help better understand brain injuries and their relation to sports. The Alberts team conducted clinical concussion testing on the same hockey players. See

Integration of genomics into primary care

Charis Eng, MD, PhD, Chair, Genomic Medicine Institute, recently commented on how physicians could use a patient’s family health history to handle the extensive genetic information coming their way through whole-genome sequencing.  She underscores the fact that having a genetic predisposition to disease doesn’t mean the individual will get the disease.  Instead, this information can help tailor treatment and disease prevention plans.  See

Genetic test for autism

Thomas Frazier, PhD, Center for Pediatric Behavioral Health, was interviewed regarding a study he leads in collaboration with Charis Eng, MD, PhD, Chair, Genomic Medicine Institute, aiming to develop a genetic test for autism.  Identifying the complex genetic factors contributing to autism is hoped to promote earlier diagnoses, better treatment, and improved outcomes.  See video at

Lauded cancer-tracking technique

As part of the “Eyes on cancer:  techniques for watching tumors do their thing” article in The Scientist, Justin Lathia, PhD, Cell Biology, is featured giving the details on intravital microscopy, which allows real-time tracking of tumor growth.  It was this technique that led to his ground-breaking 2011 paper in PLoS ONE, in collaboration with Jeremy Rich, MD, Chair, Stem Cell Biology and Regenerative Medicine, and Alex Huang, MD, PhD, Case Western Reserve University, which demonstrated for the first time a functional definition for stem cells in building tumor mass.  See

Notable mentions

Richard Ransohoff, MD, Neurosciences, was featured – twice – in the Spring 2012 issue of the National Multiple Sclerosis Society’s quarterly update on MS research.  The first mention praised his collaboration with Claudia Lucchinetti, MD, Mayo Clinic, on their international team’s study published in the New England Journal of Medicine that showed paradigm-shifting evidence of how MS develops.  Secondly, Dr. Ransohoff was commended for having won the 2012 Dystel Prize for MS research.

Another approach to personalized healthcare

Medical Device Solution’s 3-D printer was the subject of a recent Plain Dealer article, featuring Karl West and Ryan Klatte of MDS, Dr. Roy Greenberg, Vascular Surgery, and Dr. Samir Kapadia, Cardiovascular Medicine.  The 3-D object that results from this ‘printer’ based on information from a patient’s CT scans is instrumental in planning surgery, customizing grafts, and testing other devices in life-sized, personalized models of patients’ organs.  See

Cause found for pregnancy-induced hypertension

Researchers led by Qingyu Wu, MD, PhD, Molecular Cardiology, discovered that the heart enzyme corin and the hormone it activates are responsible for preventing pregnancy-induced hypertension, a condition known as pre-eclampsia. In experimental models lacking either component, pre-eclampsia-like symptoms emerged. Likewise, pre-eclamptic patients were also found to have corin deficiencies, and corin gene mutations were identified. The new findings, published in Nature suggest better ways to diagnose and treat pre-eclampsia. See;;;;;