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15 Researchers Receive Grants Totaling More than $16 Million

Fifteen Institute researchers recently received new grants totaling more than $16 million. The recipients are:

Suneel Apte, MBBS, DPhil, Biomedical Engineering, was awarded $337,500 over 1 year for "Biological Roles of ADAMTS Proteases." Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH.

Gerald Beck, PhD, Quantitative Health Sciences, was awarded grants for two Data Coordinating Centers. He received $528,558 in supplemental funding over 2 years for "Hemodialysis Fistula Maturation Consortium Data Coordinating Center." Funded by the National Institute for Diabetes and Digestive and Kidney Diseases/NIH under the American Recovery and Reinvestment Act of 2009. Dr. Beck also was awarded $262,236 in supplemental funding for "Hemodialysis Network Data Coordination Center." Funded by the National Institute for Diabetes and Digestive and Kidney Diseases/NIH.

Brian Davis, PhD, Biomedical Engineering, was awarded $2,998,909 over 3 years for "Nitinol Commercialization Accelerator." Funded by the Ohio Department of Development.

Carol de la Motte, PhD, Pathobiology, was awarded $2,094,113 over 5 years for "Hyaluronan Regulation of Microbial Host Defense of the Intestine." Funded by the Eunice Kennedy Shriver National institute of Child Health and Human Development/NIH.

Serpil Erzurum, MD, Chair, Pathobiology, was awarded $177,761 over 1 year for "A Phase II Study in Patients with Asthma to Assess the Safety and Immunogenicity of an Unadjuvanted Novartis H1N1 Influenza Vaccine Administered at Two Dose Levels" as a supplement to her current R01 grant "Redox Determinants of Severe Asthma." Funded by the National Heart, Lung and Blood Institute/NIH. Dr. Erzurum also received $415,578 over 2 years for "Imaging Inflammation in Asthma." This award was a challenge grant issued under the American Recovery and Reinvestment Act (ARRA).

Kiyotaka Fukamachi, MD, PhD, Biomedical Engineering, was awarded $302,112 over 1 year for "Wireless Pressure Monitoring Device." Funded by Endotronix Inc. Dr. Fukamachi also was awarded $188,546 over 1 year for "Mitral Spacer." Funded by Cardiosolutions, Inc.

Linda Graham, MD, Interim Chair, Biomedical Engineering, was awarded $465,073 over 1 year for "Effects of Lipids on Vascular Graft Healing." Funded by the National Heart, Lung and Blood Institute/NIH.

Satish Kalhan, MD, Pathobiology, was awarded $730,681 for 2 years for "Sulfur Amino Acid Metabolism in NAFLD." The grant was funded under the American Recovery and Reinvestment Act and distributed via the National Institute of Diabetes and Digestive and Kidney Diseases.

Vinod Labhasetwar, PhD (Co-PI), Biomedical Engineering, received more than $2 million over 3 years from the U.S. Department of Defense for work developing a nanoparticle delivery system to selectively target leukemia stem-cells but not normal hematopoietic stem-cells so that the therapy is less toxic and more effective.

Bruce Lamb, PhD, Neurosciences, was awarded $1,609,250 over 5 years for "Modifiers of Beta-Amyloid Metabolism and Deposition (R01)." Funded by the National Institute on Aging/NIH.

Edward Maytin, MD, PhD, Biomedical Engineering, was awarded $333,065 over 1 year for "Hyaluronan in Epidermal Injury Responses." Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH.

Laura Nagy, PhD, Pathobiology, was awarded $1,512,735 over 5 years for "Alcoholic Liver Disease: Biochemical, cellular and systemic responses to ethanol" (P20, Exploratory/Developmental Alcohol Research Center). Funded by the National Institute on Alcohol Abuse and Alcoholism/NIH.

Robert Silverman, PhD, Cancer Biology, was awarded $499,999 over 2 years for "Amplification of Antiviral Innate Immunity by Suppressor of Virus RNA (svRNA)." Funded under the American Recovery and Reinvestment Act and distributed via the National Institute of Allergy and Infectious Diseases/NIH.

Jerrold Vitek, MD, PhD, Neurosciences, has been awarded three grants: supplemental funding of $399,071 over 2 years for "Deep Brain Stimulation in the Parkinsonian Monkey" (R01, competitive revision); $715,000 over 2 years for "Pathophysiology of Dystonia" (R01); and $717,470 over 2 years for "DBS of the Pedunculopontine Nucleus in Parkinsonian Primate" (IRC). All were funded by the National Institute of Neurological Disorders and Stroke/NIH.

Maciej Zborowski, PhD, Biomedical Engineering, was awarded $128,397 over 1 year for "Magnetophoretic Cell Sorting Analysis." Funded by the National Cancer Institute/NIH.