Department of Pathobiology

Pathobiology researchers serve the national and the global community by dedication to the solution of problems in human health through discovery, application, and education. Our goals are to enhance prevention, treatment and cures through research, and to develop innovative clinical programs for treating patients. The common research theme and the multi-disciplinary creative investigators in Pathobiology assure a continued high degree of successful collaborations, discoveries and innovation that allow us to realize these goals.

Department News

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Events Calendar

  • May 24th 2016
    Pathobiology Seminar Series: "Skeletal muscle stem cell regulation by the TRAF6-TAK1 axis"
    Ashok Kumar, PhD, Professor and Distinguished University Scholar, Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, Kentucky
  • May 10th 2016
    Pathobiology Seminar Series: "Approaching the Gene-specific Treatment of Autoimmunity at the MIF Locus"
    Richard Bucala, MD, PhD, Professor of Medicine (Rheumatology), of Epidemiology (Microbial Diseases) and of Pathology, Yale University, New Haven, Connecticut
  • May 3rd 2016
    Pathobiology Seminar Series: "Extrapulmonary Microvascular Dysfunction in Pulmonary Arterial Hypertension"
    Adriano Tonelli, MD, Associate Staff, Pulmonary Medicine, Respiratory Institute, Cleveland Clinic
  • April 28th 2016
    Pathobiology Seminar Series: "Regulation of hepatic metabolism by insulin and metformin"
    Ling He, MD, PhD, Assistant Professor, Division of Metabolism, Department of Pediatrics, Johns Hopkins University School of Medicine
  • April 26th 2016
    Pathobiology Seminar Series: ""Measuring and Tuning Mammalian Heart Renewal"
    Samuel E. Senyo, PhD, Assistant Professor, Biomedical Engineering Department, Case Western Reserve University, Cleveland, Ohio
  • May 10th 2012
    17th Annual Diabetes Day:Nonclassic Diabetes Treatment, Monitoring, and Complications

    InterContinental Hotel and Bank of America Conference Center, Cleveland, Ohio
  • May 13th 2011
    6th Annual Obesity Research Day
    Featuring keynote lectures by:
    Dr. Larry Mandarino, Arizona State University
    Dr. James Levine, CWRU
    Dr. Stan Hazen, Cleveland Clinic
    Dr. John Gunstad, Kent State University
    Lerner Research Institute, NA5-08
  • March 22nd 2011
    Pathobiology Seminar Series
    Charles Thodeti, PhD, Assistant Professor, Department of Pharmacy, Northeastern Ohio Universities Colleges of Medicine
  • March 8th 2011
    Pathobiology Seminar Series
    Derek Abbott, MD, PhD, Assistant Professor, Department of Pathology, Case Western Reserve University Medical School
  • March 1st 2011
    Pathobiology Seminar Series
    Steve Kleeberger, PhD, Chief, Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health

The Department of Pathobiology is home to a multi-disciplinary team of scientists who are dedicated to the study of disease at fundamental levels, as well as to the application of that knowledge.

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The department serves as a bridge between basic biomedical research and clinical medicine and facilitates new scientific knowledge in an environment where it can be translated into direct benefits for patients. The theme of laboratory research in the department is inflammation and repair, that when dysregulated form the common denominators of human disease.

Our mission is the discovery of mechanisms and origins of human disease and the use of that knowledge to develop basic and applied strategies for prevention, detection and control of diseases.

Capitalizing on the clinical strengths at the Cleveland Clinic, many of our programs include translational and clinical components related to these diseases. Several centers of study are focused on disease topics in collaboration with colleagues in the IBD center, Respiratory Institute, Liver Disease Research

The Department has grown substantially since its inception in 2004 through the recruitment of new staff, and the reorganization of clinical research at Cleveland Clinic. There are 25 staff members, 7 project staff, 7 adjunct staff, 5 research associates and more than 100 support personnel in Pathobiology with laboratories housed on the 2nd floor of the Lerner Research Institute NC building, NB2, NE4, and A50. The Department members of the Clinical Research Unit of the Clinical and Translational Science Award (CTSA) are housed in M51 of the hospital and serve the Cleveland Clinic campus.