Department of Pathobiology

Pathobiology researchers serve the national and the global community by dedication to the solution of problems in human health through discovery, application, and education. Our goals are to enhance prevention, treatment and cures through research, and to develop innovative clinical programs for treating patients. The common research theme and the multi-disciplinary creative investigators in Pathobiology assure a continued high degree of successful collaborations, discoveries and innovation that allow us to realize these goals.

Department News

[ see news archive ]

Events Calendar

  • January 27th 2015
    Pathobiology Department Seminar Series: "CrossFit exercise training for the treatment of type 2 diabetes: promising results from a pilot study"
    CiarĂ¡n Fealy, BSc, PhD Candidate, Kirwan Lab
  • January 20th 2015
    Pathobiology Department Seminar Series: "How cell death triggers fibrosis and cancer in the liver"
    Robert Schwabe, MD, Assistant Professor of Medicine, Columbia University, New York
  • November 18th 2014
    "SIRT1-lipin-1 Signaling and Alcoholic Steatohepatitis"
    Min You, PhD Professor & Chair of Department of Pharmaceutical Sciences Associate Dean for Research, College of Pharmacy Northeast Ohio Medical University (NEOMED)
  • September 30th 2014
    "ADAP is Critical for SLP76 Microcluster Assembly and Signal Transduction in T cells"
    Nathan P. Coussens, Ph.D. Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
  • September 16th 2014
    "Mechanisms of Site-selective Protein S-Nitrosylation"
    Paul Fox, PhD, Staff, Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic
  • May 10th 2012
    17th Annual Diabetes Day:Nonclassic Diabetes Treatment, Monitoring, and Complications

    InterContinental Hotel and Bank of America Conference Center, Cleveland, Ohio
  • May 13th 2011
    6th Annual Obesity Research Day
    Featuring keynote lectures by:
    Dr. Larry Mandarino, Arizona State University
    Dr. James Levine, CWRU
    Dr. Stan Hazen, Cleveland Clinic
    Dr. John Gunstad, Kent State University
    Lerner Research Institute, NA5-08
  • March 22nd 2011
    Pathobiology Seminar Series
    Charles Thodeti, PhD, Assistant Professor, Department of Pharmacy, Northeastern Ohio Universities Colleges of Medicine
  • March 8th 2011
    Pathobiology Seminar Series
    Derek Abbott, MD, PhD, Assistant Professor, Department of Pathology, Case Western Reserve University Medical School
  • March 1st 2011
    Pathobiology Seminar Series
    Steve Kleeberger, PhD, Chief, Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health

The Department of Pathobiology is home to a multi-disciplinary team of scientists who are dedicated to the study of disease at fundamental levels, as well as to the application of that knowledge.

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The department serves as a bridge between basic biomedical research and clinical medicine and facilitates new scientific knowledge in an environment where it can be translated into direct benefits for patients. The theme of laboratory research in the department is inflammation and repair, that when dysregulated form the common denominators of human disease.

Our mission is the discovery of mechanisms and origins of human disease and the use of that knowledge to develop basic and applied strategies for prevention, detection and control of diseases.

Capitalizing on the clinical strengths at the Cleveland Clinic, many of our programs include translational and clinical components related to these diseases. Several centers of study are focused on disease topics in collaboration with colleagues in the IBD center, Respiratory Institute, Liver Disease Research

The Department has grown substantially since its inception in 2004 through the recruitment of new staff, and the reorganization of clinical research at Cleveland Clinic. There are 25 staff members, 7 project staff, 7 adjunct staff, 5 research associates and more than 100 support personnel in Pathobiology with laboratories housed on the 2nd floor of the Lerner Research Institute NC building, NB2, NE4, and A50. The Department members of the Clinical Research Unit of the Clinical and Translational Science Award (CTSA) are housed in M51 of the hospital and serve the Cleveland Clinic campus.